Drug disposition and pharmacokinetics : from principles to applications / Stephen H. Curry, Robin Whelpton.

Format:

Book

Author/Creator:

Curry, Stephen H.

Contributor:

Whelpton, Robin.

Wiley InterScience (Online service)

Louis B. Flexner Medical Book Fund.

Language:

English

Subjects (All):

Pharmacokinetics.

Biopharmaceutics.

Drugs--Metabolism.

Drugs.

Pharmaceutical Preparations--metabolism.

Medical Subjects:

Pharmacokinetics.

Biopharmaceutics.

Pharmaceutical Preparations--metabolism.

Physical Description:

1 online resource (xix, 365 pages) : illustrations.

Edition:

2ND ED.

Place of Publication:

Chichester, West Sussex : Wiley-Blackwell, 2011.

Contents:

Chemical introduction : sources, classification, and chemical properties of drugs

Drug administration and distribution

Drug elimination

Elementary pharmacokinetics

More complex and model independent pharmacokinetic models

Kinetics of metabolism and excretion

Further consideration of clearance, and physiological modelling

Drug formulation : bioavailability, bioequivalence and controlled-release preparations

Factors affecting plasma concentrations

Pharmacogenetics and pharmacogenomics

Developmental pharmacology and age-related phenomena

Effects of disease on drug disposition

Quantitative pharmacological relationships

Simultaneous measurement of concentrations and effect, and pharmacokinetic/pharmacodynamic (PK/PD) modelling

Drug monitoring in therapeutics

Drug interactions

Drug metabolism and pharmacokinetics in toxicology.

Notes:

Includes bibliographical references and index.

Electronic reproduction. Hoboken, N.J. Available via World Wide Web.

Print version record.

Local Notes:

Acquired for the Penn Libraries with assistance from the Louis B. Flexner Medical Book Fund.

Other Format:

Print version: Curry, Stephen H. Drug disposition and pharmacokinetics.

ISBN:

9781119589181

1119589185

9781119589198

Publisher Number:

99994498819

Access Restriction:

Restricted for use by site license.