Advances in Radiation Oncology in Lung Cancer / edited by Branislav Jeremić.

Format:

Book

Contributor:

Jeremić, Branislav, editor.

Series:

Radiation Oncology, 2731-4723

Language:

English

Subjects (All):

Medical radiology.

Oncology.

Radiology.

Respiratory organs--Diseases.

Respiratory organs.

Radiation Oncology.

Pneumology.

Local Subjects:

Radiation Oncology.

Radiology.

Oncology.

Pneumology.

Physical Description:

1 online resource (1128 pages)

Edition:

3rd ed. 2023.

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2023.

Summary:

This is the third, completely updated edition of a comprehensive book in which many of the world’s leading lung cancer specialists discuss the recent advances in the radiation oncology of lung cancer and reflect on the latest research findings in lung cancer and other intrathoracic malignancies. Lung cancer remains the major cancer killer in both sexes worldwide. It is so despite significant progress in recent decades in both diagnostic and treatment approaches. New biological and technological advances in this field are now faster incorporated in the overall decision-making process and are bringing fast and substantial improvements in both survivals and quality of life of lung cancer patients. Optimized patient-oriented approaches are reality of the third decade of this millennium and thoracic oncologists strive towards nothing but seamlessly delivering it in a continuous battle with lung cancer. The first three sections of the work cover the basic science of lung cancer, clinical investigations, including histology and staging, and a wide range of fundamental treatment considerations. Current treatment strategies for small cell and non-small cell lung cancer as well as other intrathoracic malignancies are then explained and evaluated in detail, with due attention to novel approaches that promise further improvements in outcome. The various types of treatment-related toxicity are discussed, and quality of life studies and prognostic factors are also considered. After evaluating the latest technological and biological advances, including stereotactic radiotherapy, and particle therapy, the book concludes by thorough consideration of specific aspects of clinical research in lung cancer. This concise yet comprehensive book is an invaluable resource for radiation oncologists.

Contents:

Part I: Basic Science of Lung Cancer

Genomic Alterations in Lung Cancer

Epigenetic Events in Lung Cancer

Part II: Clinical Investigations

Interventional Pulmonology

Pathology of Lung Cancer

Role of Radiologic Imaging in Lung Cancer

Place and Role of PET/CT in the Diagnosis and Staging of Lung Cancer

Surgical Staging of Lung Cancer

Part III: Basic Treatment Considerations

Surgery in Lung Cancer

Radiobiology of the Normal Lung Tissue and Lung Tumors

Radiotherapy of Lung Cancer: Impact of Time, Dose, and Fractionation

Medical Physics of Radiation Therapy of Lung Cancer

Tumor Motion Control

PET and PET/CT in Treatment Planning

The Radiation Target in Non-Small Cell Lung Cancer

The Radiation Target in Small-Cell Lung Cancer

Radiation Sensitizers

Radioprotectors and Chemoprotectors in the Management of Lung Cancer

Classic Chemotherapy for Lung Cancer

Targeted Therapy for Lung Cancer

Immunotherapy for Lung Cancer

Combined Radiotherapy and Chemotherapy: Theoretical Considerations and Biological Premises

Mechanisms of Action of Radiotherapy and Immunotherapy in Lung Cancer: Implications for Clinical Practice

Part IV: Current Treatment Strategies in Early-Stage Non-Small Cell Lung Cancer

Early Non-small Cell Lung Cancer: The Place of Radical Non-SABR Radiation Therapy

Never-Ending Story: Surgery Versus SBRT in Early-Stage NSCLC

Stereotactic Ablative Radiotherapy for Early-Stage Lung Cancer

Role of Postoperative Radiation Therapy in Non-Small Cell Lung Cancer

Photodynamic Therapy (PDT) as Treatment Option in Lung Cancer

The Role of Thermal Ablation in the Treatment of Stage I Non-Small Cell Lung Cancer

Part V: Current Treatment Strategies in Locally Advanced and Metastatic Non-Small Cell Lung Cancer

Lung Dose Escalation

Multimodality Treatment of Stage IIIA/N2 NSCLC - Why Always NO to Surgery

Multimodality Treatment of Stage IIIA/N2 NSCLC: When YES to Surgery

Combined Radiation Therapy and Chemotherapy as an Exclusive Treatment Option in Locally Advanced Inoperable Nonsmall Cell Lung Cancer

Do New Drugs Offer Hope for Maintenance/Consolidation Therapy Given After Concurrent Radiochemotherapy?

Prophylactic Cranial Irradiation in Locally Advanced Nonsmall Cell Lung Cancer

Palliative Thoracic Radiotherapy of Non-Small Cell Lung Cancer

Intraoperative Radiotherapy in Lung Cancer

Brachytherapy for Lung Cancer

Oligometastatic Disease – Basic Aspects and Clinical Results

Part VI: Current Treatment Strategies in Small Cell Lung Cancer

Radiation Therapy in Limited Disease Small Cell Lung Cancer

Role of Thoracic Radiation Therapy in Extensive Disease Small Cell Lung Cancer

Prophylactic Cranial Irradiation in Small Cell Lung Cancer

Part VII: Treatment in Specific Patient Groups and Other Settings

Role of Radiation Therapy for Lung Cancer in Elderly

Lung Cancer Recurrence Treated with Radiation Therapy

Treatment of Second Lung Cancers

Radiation Therapy for Metastatic Lung Cancer - Brain Metastasis

Radiation Therapy for Metastatic Lung Cancer - Bone Metastasis and Metastatic Spinal Cord Compression

Radiation Therapy for Metastatic Lung Cancer - Liver Metastasis

Advances in Supportive and Palliative Care for Lung Cancer Patients

Part VIII: Other Intrathoracic Malignancies

Thymic Cancer

Mesothelioma

Tracheal Tumors

Pulmonary Carcinoid

Part IX: Treatment-Related Toxicity

Hematological Toxicity in Lung Cancer

Radiation Therapy-Induced Lung and Heart Toxicity

Spinal Cord Toxicity

Radiation Induced Esophageal Toxicity

Brain Toxicity

Part X: Quality of Life Studies and Prognostic Factors

Quality of Life Outcomes in Radiotherapy of Lung Cancer

Importance of Prognostic Factors in Lung Cancer

Part XI: Technological Advances in Lung Cancer

Intensity-Modulated Radiation Therapy and Volumetric-Modulated Arc Therapy for Lung Cancer

Image-Guided Radiotherapy in Lung Cancer with Kilovoltage and Megavoltage Treatment Planning and Delivery

Heavy Particles in Nonsmall Cell Lung Cancer

Heavy Particles in Nonsmall Cell Lung Cancer: Carbon Ions

The Role of Nanotechnology for Diagnostic and Therapy Strategies in Lung Cancer

Part XII: Clinical Research in Lung Cancer

Translational Research in Lung Cancer

Radiation Oncology of Lung Cancer: Why We Fail(ed) in Clinical Research?

Randomized Clinical Trials: Pitfalls in Design, Analysis, Presentation, and Interpretation.

Notes:

Includes bibliographical references.

Other Format:

Print version: Jeremić, Branislav Advances in Radiation Oncology in Lung Cancer

ISBN:

3-031-34847-8