Essentials of mucosal immunology / edited by Martin F. Kagnoff, Hiroshi Kiyono.

Format:

Book

Conference/Event

Contributor:

Kagnoff, M. F. (Martin F.)

Kiyono, H. (Hiroshi)

Conference Name:

International Congress on Mucosal Immunology (8th)

Language:

English

Subjects (All):

Mucous membrane--Immunology--Congresses.

Mucous membrane.

Generative organs--Immunology--Congresses.

Generative organs.

Physical Description:

1 online resource (633 p.)

Other Title:

Mucosal immunology

Place of Publication:

San Diego : Academic Press, c1996.

Language Note:

English

Summary:

Essentials of Mucosal Immunology presents basic concepts as well as new and exciting advances in mucosal immunology and inflammation, the development of mucosal vaccines, and the role of the immune system in mucosal disease. Specific chapters highlight novel approaches to the treatment of autoimmune disease, including the use of oral tolerance; approaches to and vectors for new vaccines; and current concepts in mucosal inflammation and its role in inflammatory bowel disease and ulcer disease.Key Features* Contains the most current research on mucosal immunology and is compre

Contents:

Front Cover; Essentials of Mucosal Immunology; Copyright Page; Contents; Contributors; Preface; Acknowledgments; Part I: Antigen Processing and Presentation in Mucosal-Associated Tissue; Chapter 1. Principles of Antigen Processing and Presentation; I. Introduction; II. Antigen Processing and Presentation by MHC Class I Molecules; III. Antigen Processing and Presentation by MHC Class II Molecules; IV. Antigen Presentation by Nonclassical Class I Molecules; V. Peptide Binding by Class I, Class II, and Nonclassical Class I Molecules; VI. Conclusions; References

Chapter 2. M Cells as a Pathway for Antigen Uptake and ProcessingI. Introduction; II. The Follicle-Associated Epithelium and M Cells; III. M Cell Membranes; IV. Local Antigen Uptake and Regional Immune Responses; V. Interactions of Microorganisms with M Cells; VI. Conclusion; References; Chapter 3. Toward an in Vitro Model for Microorganism Transport and Antigen Sampling through the Epithelial Digestive Barrier; I. Introduction; II. Epithelial Origin of M Cells; III. Experimental Approaches to Induce FAE Properties and M Cell Formation; IV. Conclusions; References

Chapter 4. Role of Dendritic Cells, Macrophages, and yd T Cells, in Antigen Processing and Presentation in the Respiratory MucosaI. Introduction; II. Dendritic Cells; III. Endogenous Tissue Macrophages in Regulation of the Local Expression of T-Cell Immunity; IV. CD8+ T-Cell Regulation of Primary Immune Responses to Inhaled Antigen; References; Chapter 5. Nonprofessional Antigen Presentation: New Rules and Regulations; References; Part II: Role of Epithelial Cells in Mucosal Immunity; Chapter 6. Intestinal Epithelial Cells: An Integral Component of the Mucosal Immune System; I. Introduction

II. Regulated Production of Proinflammatory Cytokines by Human Colon Epithelial CellsIII. Cytolytic Pathogens: A Further Paradigm for Upregulation of Proinflammatory Cytokines by Intestinal Epithelial and Stromal Cells; IV. Expression of Adhesion Molecules on Colon Epithelial Cells Following Microbial Invasion; V. Summary; References; Chapter 7. Bacterial Activation of Mucosal Cytokine Production; I. Introduction; II. Infection and Epithelial Cytokine Responses; III. Role of the Ceramide Signaling Pathway in the Cytokine Responses to P-Fimbriated Escherichia coli

IV. Do P-Fimbriated Escherichia coli Invade Uroepithelial Cells?V. Epithelial Cells in Mucosal Cytokine Networks; VI. Neutrophil Recruitment to the Mucosa; VII. Role of Mucosal Inflammation and Neutrophil Influx in the Clearance of UTI; References; Chapter 8. MHC-like Molecules on Mucosal Epithelial Cells; I. Summary; II. Structure and Function of MHC Class Ia Molecules; III. Structure and Function of MHC Class Ib Molecules; IV. The Human Intestinal Epithelial Compartment; V. The FcRn in the Human Intestine; VI. CD1 in the Human Intestine; References

Chapter 9. Regulatory Peptides and Integration of the Intestinal Epithelium in Mucosal Responses

Notes:

Expanded and reviewed papers presented at the 8th International Congress of Mucosal Immunology.

Includes bibliographical references and index.

ISBN:

1-281-02935-1

9786611029357

0-08-053124-5

OCLC:

476098583