Male and female infertility : genetic causes, hormonal treatments and health effects / Bjorn Glantz and Klas Edquist, editors.

Format:

Book

Contributor:

Glantz, Björn.

Edquist, Klas.

Series:

Human reproductive system--anatomy, roles, and disorders series.

Human reproductive system -- anatomy, roles and disorders

Language:

English

Subjects (All):

Infertility.

Physical Description:

1 online resource (228 p.)

Place of Publication:

New York : Nova Biomedical Books, 2010.

Language Note:

English

Summary:

Infertility is a major increasing concern. As the male factor contributes to about half of the infertility cases, sperm analysis is extremely important for diagnosis and investigation of infertility. In this book, the cytometric techniques used to evaluate sperm DNA/chromatin integrity together with some other functional properties of the male gamete are described and advantages and limitations are discussed. In addition, the authors provide an overview of how antioxidative and redox systems participate in spermatogenesis and in pathological conditions, such as heat stress, in the testes. Oxidative stress-induced damage to both oocytes in vivo and embryos in culture are also examined, as well as the role of ROS signaling in embryo development. Furthermore, endometriosis is an estrogen-dependent disease which affects 6% to 30% of women in reproductive age and is associated with infertility in approximately 60% of cases. In this book, classic and recently proposed etiopathogenic mechanisms or endometriosis-related infertility are discussed, as well as some aspects of its clinical investigation and medical treatment. Other chapters in this book assess the capability of combining of Anti-Mullerian hormone (AMH) and embryo quality as predictors of pregnancy outcome and an examination of how the use of animal models can help us to understand the female reproductive system and the etiology of some female infertile disorders.

Contents:

Flow cytometric analyses of sperm functions and genetic integrity / Helena Oliveira ... [et al.]

Requirement of multiple antioxidative/redox systems to support male fertility / Junichi Fujii, Yoshihito Iuchi

Active oxygen species as a signal of embryonic developmental arrest and death / Naoko Kimura ... [et al.]

Endometriosis-related infertility : etiopathogeny, clinical aspects, and non-surgical approach / Bruno Ramalho de Carvalho

Developments in the debate on assisted reproduction : a gender perspective / Manuela Perrotta

Animal models for studying female infertility / Paloma Sanchez-Aparicio

The fallopian tube involvement in the reproductive process / Sergio Ghersevich

The relevance of serum anti-Mullerian hormone levels, chronological age, and embryo quality to the outcome of assisted reproduction technology cycles / Tsung-Hsien Lee ... [et al.]

Evidence for decline in male infertility with increasing age : effect on spermatogenesis and genetic package / Fabio F. Pasqualotto ... [et al.]

Gene therapy for male infertility : potential and limitation / Yoshiyuki Kojima ... [et al.].

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-61324-689-7