Molecular principles of fungal pathogenesis [electronic resource] / edited by Joseph Heitman ... [et al.].

Format:

Book

Contributor:

Heitman, Joseph.

Language:

English

Subjects (All):

Pathogenic fungi--Molecular aspects.

Pathogenic fungi.

Histology, Pathological.

Physical Description:

1 online resource (710 p.)

Place of Publication:

Washington, D.C. : ASM Press, c2006.

Language Note:

English

Summary:

Molecular Approaches of Fungal Pathogenesis presents readers with a compendium of research in the field of medical mycology, measures the impact of genome projects, genetics, and molecular biology on the understanding of a diverse group of pathogenic fungi, and explores the potential impact of vaccines and new therapeutic approaches to treatment.

Contents:

Fungal molecular pathogenesis : what can it do and why do we need it? / John R. Perfect and Arturo Casadevall

Sex, MAT, and the evolution of fungal virulence / James A. Fraser and Joseph Heitman

Postgenomic strategies for genetic analysis : insight from Saccharomyces cerevisiae and Candida albicans / Clarissa J. Nobile and Aaron P. Mitchell

Candida albicans hypha formation and virulence / Paula Sundstrom

The conversion from classical studies in fungal pathogenesis to the molecular era / Kyung J. Kwon-Chung and Brian L. Wickes

Mating and parasexual genetics in Candida albicans / Mathew Miller and Alexander Johnson

The mating-type locus and mating of Candida albicans and Candida glabrata / David R. Soll

Evolution of human pathogenic fungi : phylogenies and species / John W. Taylor

Establishment of cell identity in pathogenic fungi / Christina M. Hull

Signal transduction in the interactions of fungal pathogens and mammalian hosts / Malcolm Whiteway and Catherine Bachewich

Function and regulation of adhesin gene families in Saccharomyces cerevisiae, Candida albicans, and Candida glabrata / Irene Castaño, Alejandro de las Peñas, and Brendan P. Cormack

Fungal biofilms : agents of disease and drug resistance / Gordon Ramage, Mahmoud A. Ghannoum, and José L. López-Ribot

Molecular basis of fungal adherence to endothelial and epithelial cells / Scott G. Filler, Donald C. Sheppard, and John E. Edwards, Jr.

Molecular principles of antifungal drug resistance / Dominique Sanglard and Theodore C. White

Heterologous hosts and the evolution and study of fungal pathogenesis / Eleftherios Mylonakis, Stephen B. Calderwood, and Frederick M. Ausubel

Amoeba and slime mold: hosts of virulence evolution / Arturo Casadevall

Aspergillus nidulans : a model for elucidation of Aspergillus fumigatus secondary metabolism / Nancy Keller

Saccharomyces cerevisiae : an emerging and model pathogenic fungus / John H. McCusker

Fungal-bacterial interactions / Deborah A. Hogan and Roberto Kolter

Amphibian chytridiomycosis as an emerging infectious disease of wildlife : what can we learn from the earliest diverging fungi? / Timothy Y. James and Rytas Vilgalys

Cryptococcus neoformans : a sugar-coated killer / John R. Perfect

Toward a molecular understanding of Candida albicans virulence / Frank C. Odds, Neil A.R. Gow, and Alistair J.P. Brown

Molecular determinants of Histoplasma capsulatum pathogenesis / Jon P. Woods

Molecular determinants of virulence in Aspergillus fumigatus / Judith C. Rhodes and Axel A. Brakhage

Pathogenesis of pneumocystis / A. George Smulian and Melanie T. Cushion

Virulence mechanisms of coccidioides / Garry T. Cole ... [et al.]

Blastomyces dermatitidis cell surface determinants and their application in vaccine development / Bruce Klein

Virulence factors in black molds with emphasis on melanin, chitin, and Wangiella as a molecularly tractable model / Paul J. Szaniszlo

Zygomycetes as agents of infectious disease in humans / Ashraf S. Ibrahim and Brad Spellberg

Signaling pathways in the dimorphic human fungal pathogen Penicillium marneffei / Alex Andrianopoulos and Sophie Zuber

Innate humoral immunity to fungi / Thomas R. Kozel

Innate and acquired cellular immunity to fungi / Luigina Romani

Acquired antibody-mediated immunity to fungi / Liise-anne Pirofski and Arturo Casadevall

Site-specific mucosal immunity to fungi : lessons learned from Candida albicans applied to other fungi / Paul L. Fidel, Jr. and Beatriz Finkel-Jimenez

Intracellular pathogenesis of Histoplasma capsulatum / Simon L. Newman

Interactions of immune cells with the facultative intracellular pathogen Cryptococcus neoformans / Lauren E. Yauch and Stuart M. Levitz

Fungal interactions with leukocytes / Mairi C. Noverr ... [et al.]

Fungal vaccine development / Joshua D. Nosanchuk and George S. Deepe Jr.

Molecular immunopathogenesis of innate host defense against chronic disseminated (hepatosplenic) candidiasis / Thomas J. Walsh ... [et al.]

Studying fungal virulence using genomics / Michael C. Lorenz

Future of functional genomics of Histoplasma capsulatum / Anita Sil and Lena Hwang

Functional genomic approaches to fungal pathogenesis, drug target validation, and antifungal drug discovery / Ainslie B. Parsons, Howard Bussey, and Charles Boone

Genetic and proteomic analysis of fungal virulence / Jennifer K. Lodge and Michael C. Lorenz

Genomic perspectives on the fungal kingdom / Jason E. Stajich and Fred S. Dietrich.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-283-03406-9

9786613034069

1-55581-577-4

OCLC:

609853107