Cell respiration and cell survival : processes, types and effects / Gijsbert Osterhoudt and Jos Barhydt, editors.

Format:

Book

Contributor:

Osterhoudt, Gijsbert.

Barhydt, Jos.

Series:

Cell biology research progress.

Cell biology research progress series

Language:

English

Subjects (All):

Cell respiration.

Pathology, Cellular.

Physical Description:

1 online resource (279 p.)

Place of Publication:

New York : Nova Biomedical Books, c2010.

Language Note:

English

Summary:

In this book, the current understanding of the mechanisms of each beta cell toxins are reviewed, reported toxin resistant insulinoma or immortalised beta cells are summarised, and the different nature of those toxin resistant cells are analysed. With advancements in cancer stem cell research, the possible involvement of stem cells enrichment after various toxin challenges is also discussed. Moreover, there is a renewed interest in the study of the function of fatty acid synthase (FASN) and fatty-acid synthesis in cancer pathogenesis. This book outlines the role of FASN in cancer development and the pre-clinical development of FASN inhibitors and their anti-tumour effects. In addition, Parkinson disease (PD) is a neurodegenerative disorder characterised by a progressive loss of the nigrostriatal dopaminergic neurons. The authors discuss the roles of oxidative modification of the proteins of mitochondrial respiration in the pathogenesis of PD. Furthermore, it has been currently understood that the key role in the physiological and regenerative restoration of adult tissues belongs to adult stems cells. Adult stem cell survival after the action ionizing radiation, hyperthermia and in the conditions of the "ischemia/reperfusion" reaction development are examined.

Contents:

Adult stem cells survival after the action of ionizing radiation, hyperthermia and in the conditions of the "ischemia/reperfusion" reaction development / A.G. Konoplyannikov, S. Ya. Proskuryakov and M.A. Konoplyannikov

Identification of specific mitochondrial proteins forming stable adducts with 4-hydroxynonenal within cardiac tissue of type-I diabetic animals : implications for bioenergetics dysfunction and onset of diabetic cardiomyopathy / Gregg DiNuoscio, Chao Yuan, Ossama Lashin and Andrea Romani

The bone marrow microenvironment in multiple myeloma : cellular and molecular basis of disease progression / R. Ria, A. Reale, G. Mangialardi, F. Dammacco, D. Ribatti and A. Vacca

Respiration and oxidative metabolism in spermatozoa / L. Pintos and M Córdoba

Plectin deficiency and human hepatocellular carcinoma / Yih-Shyong Lai and Yi-Hsiang Liu

Studies of toxin resistant beta-cells : lessons for the chemotherapy? / Liu Hui-Kang

Fatty acid metabolism in cancer cell survival : a new anti-cancer target / Rut Porta, Ramon Colomer and Teresa Puig

Impaired mitochondrial respiration as a causative factor in Parkinson's Disease / Haseeb Ahmad Khan

Ecophysiological look at organ respiration in carnivorous plants : a review / Lubomír Adamec.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

1-61122-682-1