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Pathogenesis of human pulmonary tuberculosis [electronic resource] : insights from the rabbit model / Arthur M. Dannenberg.
- Format:
- Book
- Author/Creator:
- Dannenberg, Arthur M.
- Language:
- English
- Subjects (All):
- Tuberculosis--Animal models.
- Tuberculosis.
- Tuberculosis--Pathophysiology.
- Lurie, Max B. (Max Bernard), 1893-1966.
- Medical Subjects:
- Lurie, Max B. (Max Bernard), 1893-1966.
- Physical Description:
- 1 online resource (469 p.)
- Place of Publication:
- Washington, D.C. : ASM Press, c2006.
- Language Note:
- English
- Summary:
- This work, authored by a noted and experienced expert in the field, examines the pathogenesis of human pulmonary tuberculosis in all of its stages, with a primary focus on the rabbit model. Tuberculosis in the rabbit most closely resembles that found in humans, including caseous necrosis, liquefaction, and cavity formation with bronchial spread of the disease.
- Contents:
- Stages in the pathogenesis of human and rabbit tuberculosis
- Types of human pulmonary tuberculosis
- Liquefaction of caseous foci and cavity formation
- Delayed-type hypersensitivity, cell-mediated immunity, and antibodies in tuberculosis
- Macrophages and other cells in tuberculous lesions
- Structural components of tuberculous lesions
- Microvascular density in tuberculous lesions
- Early pulmonary lesions in rabbits
- Macrophage turnover, division, and activation in tuberculous lesions
- Lurie's pulmonary Tubercle-count method
- Natural airborne infection
- Response of rabbits to inhaled tubercle bacilli including BCG
- Characteristics of resistance and susceptibility to tuberculosis in Lurie's inbred rabbits
- Comparisons of tuberculosis in rabbits, mice, and guinea pigs
- Effects of cortisone and adrenocorticotropic hormone on tuberculosis
- Effects of estrogen, chorionic gonadotropin, and thyroid hormone on tuberculosis
- Effects of whole-body X-irradiation on tuberculosis
- Cytokine production in primary BCG lesions
- Cytokine production in reinfection bcg lesions and in tuberculin reactions
- Vascular adhesion molecules in tuberculous lesions
- Principles and guidelines for developing better tuberculosis vaccines
- Characteristics of rabbit BCG lesions and efficacies of BCG and mycobacterium microti vaccines.
- Notes:
- Description based upon print version of record.
- Includes bibliographical references and index.
- ISBN:
- 1-283-03398-4
- 9786613033987
- 1-55581-568-5
- OCLC:
- 609853200
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