Applications of NMR Spectroscopy.

Format:

Book

Author/Creator:

Atta-ur-Rahman.

Contributor:

Choudhary, M. Iqbal.

Series:

Applications of NMR Spectroscopy

Language:

English

Subjects (All):

Nuclear magnetic resonance spectroscopy.

Physical Description:

1 online resource (222 pages)

Edition:

1st ed.

Place of Publication:

Singapore : Bentham Science Publishers, 2021.

Summary:

Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture. The ninth volume of the series features reviews that highlight NMR spectroscopic techniques in microbiology, food science, pharmaceutical analysis and cancer diagnosis. The reviews in this volume are: - NMR spectroscopy for the characterization of photoprotective compounds in cyanobacteria - Coffee assessment using 1H NMR spectroscopy and multivariate data analysis: a review - Evaluation of structure-property relationship of coconut shell lignins by NMR spectroscopy: from biorefinery to high-added value products - Application of NMR spectroscopy in chiral recognition of drugs - NMR-based metabolomics: general aspects and applications in cancer diagnosis.

Contents:

Cover

Title

Copyright

End User License Agreement

Contents

Preface

List of Contributors

NMR Spectroscopy For The Characterization of Photoprotective Compounds in Cyanobacteria

Abha Pandey1, Neha Kumari1, Sonal Mishra1, Jyoti Jaiswal1 and Rajeshwar P. Sinha1,*

INTRODUCTION

PRINCIPAL PHOTOPROTECTIVE COMPOUNDS IN CYANOBACTERIA

Mycosporine-Like Amino Acids (MAAs)

Scytonemin

NMR SPECTROSCOPY

One-Dimensional (1D) NMR Spectroscopy

1H NMR Spectroscopy

13C NMR Spectroscopy

15N NMR Spectroscopy

31P NMR Spectroscopy

2D-NMR Spectroscopy

Correlation Spectroscopy (COSY)

Total Correlation Spectroscopy (TOCSY)

2D J-Resolved Spectroscopy (J-Res)

Heteronuclear Single Quantum Correlation Spectroscopy (HSQC)

Heteronuclear Multiple Bond Correlation (HMBC) Spectroscopy

Some More NMR Techniques Used in Metabolite Identification

High-Resolution Magic-Angle Spinning NMR Spectroscopy (HRMAS)

Hyperpolarisation Methods

Dynamic Nuclear Polarization (DNP)

Parahydrogen-Induced Polarisation (PHIP) and Signal Amplification by Reversible Exchange (SABRE)

Fast NMR Methods

Pure-Shift NMR

LC-NMR and Other Hybrid NMR Approaches

Applications of NMR in Metabolites

Identification and Detection of Metabolite Structures

Stable Isotope Tracer Studies

Cell-based Tracing

In Vivo Spectroscopic Measurements

NMR is Used to Trace the Stable Isotope Labeling or Isotopomer Study at Specified Atomic Positions

Purity Determination of Molecules

To Check the Quality and Drug Findings Through the Natural Products

Qualitative and Quantitative Analysis of Food

NMR SPECTROSCOPY IN STRUCTURAL ELUCIDATION OF THE UV-PROTECTIVE PIGMENT SCYTONEMIN

Extraction and Purification of Scytonemin

NMR Procedure

CONCLUSION

CONSENT FOR PUBLICATION

CONFLICT OF INTEREST.

ACKNOWLEDGEMENTS

REFERENCES

Coffee Assessment Using 1H NMR Spectroscopy and Multivariate Data Analysis: A Review

Aline Coqueiro1,*, Michel R. Baqueta2, Manuela Mandrone3, Ferruccio Poli3 and Patrícia Valderrama2,*

AUTHENTICATION/VARIETIES DISCRIMINATION

AUTHENTICATION/ADULTERATION

AUTHENTICATION/GEOGRAPHICAL ORIGIN

SENSORY CLASSIFICATION OF COFFEE

OTHER APPLICATIONS OF METABOLOMICS IN COFFEE

CONCLUDING REMARKS

CONFLICT OF INTEREST

ACKNOWLEDGEMENTS

Evaluation of Structure-property Relationship of Coconut Shell Lignins by NMR Spectroscopy: From Biorefinery to High-added Value Products

Francisco Avelino1 and Diego Lomonaco2,*

INTRODUCTION TO THE LIGNIN CHEMISTRY

STRUCTURAL ELUCIDATION OF LIGNIN BY NUCLEAR MAGNETIC RESONANCE (NMR)

BIOREFINERY

The Main Lignin Extraction Processes

The Influence of Pulping Parameters on the Lignin Structure

Tuning the Lignin Functionalities in a One-Pot Process by using Different Green Solvents

General Features of the MWAOD Process

1H NMR

1H-13C HSQC

31P NMR

Scale-up of Microwave-Assisted Organosolv Delignification Process: NMR as a Quality Control Tool

1H - 13C HSQC

PRACTICAL USES OF NMR IN LIGNIN VALORIZATION

Lignin-Based Epoxy Resins: Monitoring the Glycidylation Reaction and Quantification of Oxirane Rings by NMR

Microwave-Assisted Phosphorylation of Organosolv Lignin: Potential Bio-Additives for Epoxy Resins Formulations

Microwave-Assisted Selective Acetylation of Lignin as an Eco-Designed Process for Producing a Valuable Material with Several Technological Applications

Final Considerations

Application of NMR Spectroscopy in Chiral Recognition of Drugs.

Vinod Kumar Vashistha1,*, Sonika Sethi2, Anuj Kumar1, Saeed Ahmed3 and Dipak Kumar Das1

Objective:

Introduction

Background

Method

Application

Chiral Solvating Agents (CSAs)

(ii). Chiral Lanthanide Shift Reagents (CLSR)

(iii). Chiral Derivatizing Agents (CDAs)

Scope of the Present Chapter

CHIRALITY RECOGNITION OF CHIRAL PHARMACEUTICALS

Rasagiline

Baclofen

Betaxolol

Ibuprofen

Other Carboxylic Groups Containing Drugs

NMR-Based Metabolomics: General Aspects and Applications in Cancer Diagnosis

Jeferson Santana Ursulino1, Alessandre Carmo Crispim1, Lucas Monteiro Freire2, Elton Rafael Castro Silva Matos2, Jorge Artur Peçanha de Miranda Coelho2, Manoel Alvaro Lins Neto3, Edeildo Ferreira da Silva Júnior1,4,* and Thiago Mendonça de Aquino1

SYSTEMS BIOLOGY, METABOLOME AND METABOLOMICS

Systems Biology

Metabolome

Metabolomics

NMR-BASED METABOLOMICS

Sample Collection

Phosphate Buffer Solution Containing 3-Trimethyl-Silylpropionic Acid-d4 Sodium Salt (TSP)

Sample Preparation

Serum and Blood Plasma

Urine

Fecal Water

Nuclear Magnetic Resonance (NMR)

1H NMR - Internal Reference, Water Suppression and Spectral Data Processing

Metabolite Identification

2D NMR

STATISTICAL ANALYSIS

Principal Component Analysis (PCA)

Partial Least Squares - Discriminant Analysis (PLS-DA)

Orthogonal Partial Least Squares - Discriminant Analysis (OPLS-DA)

1H NMR-BASED METABOLOMICS ASSOCIATED WITH CANCER

Breast Cancer

Pancreatic Cancer

Lung Cancer

Colorectal Cancer

FINAL CONSIDERATIONS

FUNDING

Subject Index

Back Cover.

Notes:

Description based on publisher supplied metadata and other sources.

Includes bibliographical references.

ISBN:

9789815039351

9815039350

OCLC:

1293244739