Nanotechnology driven herbal medicine for burns : from concept to application / edited by Md. Abul Barkat, Sarwar Beg, and Farhan Jalees Ahmad.

Format:

Book

Contributor:

Barkat, Abul, editor.

Beg, Sarwar, 1987- editor.

Ahmad, Farhan J., editor.

Language:

English

Subjects (All):

Burns and scalds--Treatment.

Burns and scalds.

Herbs--Therapeutic use.

Herbs.

Nanotechnology.

Physical Description:

1 online resource (195 pages)

Edition:

1st ed.

Place of Publication:

Singapore : Bentham Science Publishers, [2021]

Summary:

Burns can cause life-threatening injury and the lengthy hospitalization and rehabilitations required in burn therapy lead to higher healthcare costs. The risk of infection has also been one of the important concerns of burn wound management. The purpose of the burn wound care management is speedy wound healing and epithelization to limit the infection. The topical application of therapeutic agents is quintessential for the longevity of patients having significant burns. In recent times, research on herbal medicine for burn wound management has been vastly increased because of their safer toxicological profiles in contrast to synthetic medicines. Despite the promising therapeutic potential of herbal medicines in this area, herbal medications have some limitations which include low pharmacological activity, solubility and stability. Nanotechnology-based smart drug delivery approaches which involve the use of small molecules as nanocarriers, however, can help to overcome these biopharmaceutical challenges. This book provides an overview of plant-mediated metallic nanoparticulate systems and nanophytomedicine based therapeutic treatment modalities for burn wound lesions. Nine chapters deliver updated information about nanomedicines for burn wound therapy. Contributions are written by experts in nanomedicine and phytomedicine and collectively cover the pathophysiology of wound lesions, current and future outlook of nanomedicine based treatments for burn wound lesions, the role of biocompatible nanomaterials in burn wound management, plant-mediated synthesis of metal nanoparticles for treating burn wound sepsis, phytomedicine based nanoformulations and the phyto-informatics models involved in the wound healing process which are used to select appropriate nanotherapeutic agents. This reference serves as an accessible source of information on the topic of nanomedicine for burn treatments for all healthcare professionals (medical doctors, nurses, students trainees) and researchers in allied fields (pharmacology, phytomedicine) who are interested in this area of medicine.

Contents:

Cover

Title

Copyright

End User License Agreement

Contents

Foreword

Preface

List of Contributors

Current Status and Future Outlook of Nanotechnology-Based Therapeutic Treatment Modalities for Burn Wound Management

Rana Mazumder1 and Subhabrota Majumdar2,*

INTRODUCTION

Skin

Physiology for Burn Wounds

Burn Wound Healing

NANOMEDICINE AND ADVANCEMENT IN THERAPY FOR BURN WOUND MANAGEMENT

Metallic Nanoparticles

Polymeric Nanoparticles

Liposomal Nanoparticles

Nanoemulsion

Nanogels

Wound Dressings

Tissue Engineering

Nanostructured Topical Drug Delivery Recent Advancement as Burn Wound Therapy

CONCLUDING REMARKS AND FUTURE PROSPECT

CONSENT FOR PUBLICATION

CONFLICT OF INTEREST

ACKNOWLEDGEMENTS

REFERENCES

Nanotechnology- Mediated Delivery of Phytomedicine for Burn Wound Healing

Mohammed Aslam1, Mohammad Zaki Ahmad2, Abdul Aleem Mohammed2, Harshita3,4, Md. Abul Barkat4 and Javed Ahmad2,*

SIGNIFICANCE OF NANOTECHNOLOGY-MEDIATED DELIVERY OF PHYTOMEDICINE

DELIVERY OF PHYTOMEDICINE EXPLOITING NANOTECHNOLOGY IN BURN WOUND HEALING

Berberine

Bromelain

Silymarin

Madecassoside

Resveratrol

Epigallocatechin

Curcumin

Aloe vera

CONCLUSION

Plant Mediated Green Synthesis of Silver Nanoparticles for Burn Wound Infections

Katayoon Kalantari1,*, Alireza Kalantari2 and Thomas J. Webster1

Plant-Based Synthesis of Ag-NPs

Mechanism of Plant-Mediated Synthesis of Ag-NPs

Ag-NP Characterization Techniques

Cytotoxicity of Plant-Mediated Ag-NPs

Antimicrobial Activities of Plant-Mediated Ag-NPs

Wound Healing Process

Wound Healing Applications of Ag-NPs

Side Effects of Silver Use

SUMMARY AND FUTURE PROSPECTS.

CONSENT FOR PUBLICATION

Therapeutic Prospective of Green-synthesized Silver Nanoparticles in Burn Wound Management

S. Sumathi1,*

Wound Healing

AgNPs as Antimicrobial Agents

Green Synthesis of AgNPs

Characterization of AgNPs and its Applications

Plant Mediated Synthesis of AgNPs and its Wound Healing Activity

Microbial Organism Mediated AgNPs and its Wound Healing Activity

Mechanism of Action of Antibacterial Activity

CONCLUDING REMARKS

ACKNOWLEDGEMENT

REFERENCE

Phytochemical-Assisted Gold Nanoparticles for Burn Wound Management

Abdelgadir A. Abdelgadir1 and Pooja A. Chawla2,*

GOLD NANOPARTICLES POTENTIAL THERAPEUTIC EFFECTS ON WOUND HEALING

GREEN SYNTHESIS OF GOLD NANOPARTICLES AND CHARACTERIZATION

WOUND HEALING MECHANISM OF PHYTOCHEMICAL-ASSISTEDGOLD NANOPARTICLES

In Vitro Studies

In Vivo Studies

Therapeutic Importance of Phyto-assisted Green Synthesis of Zinc Oxide Nanoparticles in Burn Wound Management

Md. Abul Barkat1,*

Phyto-assisted Green Synthesis of Zinc Oxide Nanoparticles

Therapeutic Potential of Phyto-assisted ZnONPs in Burn Wound

Plant Mediated Synthesis of Titanium Dioxide Nanoparticles for Burn Wound Management

NANOPARTICLE'S POTENTIAL THERAPEUTIC EFFECTS ON WOUND HEALING

GREEN SYNTHESIS OF TITANIUM DIOXIDE NANOPARTICLES AND CHARACTERIZATION

TITANIUM DIOXIDE PLANT-BASED NANOPARTICLES.

APPLICATIONS OF PLANT TITANIUM DIOXIDE NANOPARTICLES FOR WOUND HEALING

In vitro Studies

In vivo Studies

Toxicity Related to Phytochemical-assisted Metallic Nanoparticles in Burn Wound Management

Lubna Abidin1, Mohd. Mujeeb1,* and Md. Abul Barkat2

CLASSIFICATION OF BURN WOUNDS

THE RESTORATION CASCADE

NANOPARTICLES IN BURN WOUND TREATMENT

PENETRATION OF PMNPS THROUGH DERMAL ROUTE

Intracellular Pathway

Intercellular Pathway

Follicular Pathway

TOXICITY CAUSED BY PMNPS IN BURN WOUNDS

Mechanism of PMNPs Toxicity

Production of ROS

Inflammatory Cascade

Genotoxicity

Autophagy

Apoptosis

Epigenetic Effects

Phototoxicity

Neurotoxicity

Skin Sensitivity by Metallic NPs

ACKNOWLEDGEMNT

A Novel Herbal Informatic Approach for the Management of Skin Burn Injury

Ankit Tanwar1,*, Ruby Sharma2, Ayesha Ali Zaidi3, Deepti Sharma4, Rashmi Wardhan6, Raman Chawla4, Himanshu Ojha4, Rajesh Arora5 and Haider Ali Khan3

Types of Wounds and Their Healing Mechanism

Side Effects of Skin Burn Injury

Biomarkers of the Skin Wounds

METHODOLOGY

Classic Literature Surge Model

Evaluation of Relevance Factor Using 'Keywords Hits' Scoring Matrix Approach

Binary Coefficients Matrix to Assess the Presence/Absence of a Bioactivity Parameter (BAP)

Weightage Matrix-Based Analysis

Fuzzy Set Optimization for the Decision Matrix

RESULTS

Bioactivity Parameters Analysis Using the Classical Approach

Keywords Hit Scoring Matrix Approach to Evaluate the Relevance Factor

Simple Additive Weighting Matrix

Decision Matrix-Based Optimization

DISCUSSION

CONCLUSION.

CONFLICTS OF INTEREST

Subject Index

Back Cover.

Notes:

Description based on publisher supplied metadata and other sources.

Description based on print record.

Includes bibliographical references.

Other Format:

Print version: Barkat, Abul Nanotechnology Driven Herbal Medicine for Burns: from Concept to Application

ISBN:

9789815039597

9815039598

OCLC:

1293263285