Stem cell, regenerative medicine, and cancer / Shree Ram Singh editor.

Format:

Book

Contributor:

Singh, Shree Ram.

Series:

Environmental Science, Engineering and Technology

Cell biology research progress

Cancer etiology, diagnosis and treatments

Language:

English

Subjects (All):

Stem cells--Therapeutic use.

Stem cells.

Regenerative medicine.

Cancer.

Physical Description:

1 online resource (779 p.)

Place of Publication:

Hauppauge, N.Y. : Nova Science Publishers, c2011.

Language Note:

English

Summary:

Of the estimated trillion cells that build up our bodies, only a little number can self-renew and give rise to many different cell types. These unspecialised cells are called stem cells. This title focuses on the application of stem cells in regeneration and repair of the organs in disease and ageing.

Contents:

""STEM CELL, REGENERATIVE MEDICINE AND CANCER ""; ""STEM CELL, REGENERATIVE MEDICINE AND CANCER ""; ""Contents""; ""Preface ""; ""Contributors ""; ""Part I. Stem Cells in Tissue Regeneration and Repair ""; ""Epigenetic Modifications in Reprogramming and Lineage Specifications from Embryonic Stem Cells: Current Trends and Relevance in Developing Regenerative Medicine ""; ""Abstract ""; ""1. Stem Cells""; ""1.2. Embryonic Stem Cells and Their Differentiation ""; ""1.3. Adult Stem Cells ""; ""2. The Epigenetic Studies in Stem Cells""; ""2.1. DNA Methylation ""; ""2.2. Histone Modifications ""

""3. Cellular Reprogramming """"3.1. Lineage Reprogramming ""; ""3.2. Cloning and Cellular Therapy""; ""3.3. Somatic Cell Nuclear Transfer (SCNT) ""; ""3.4. SCNT: Reproductive Cloning ""; ""3.5. Ectopic Expression of Stem Cell Genes (Induction of Pluripotency) ""; ""4. Regenerative Medicine ""; ""4.1. Gene Therapy ""; ""hESCs and Gene therapy ""; ""4.2. Cellular Therapy ""; ""Conclusion""; ""References ""; ""Regenerative Medicine: Lessons from Planarians""; ""Abstract ""; ""1. Introduction""; ""2. Planarian Stem Cells: The Neoblasts ""; ""2.1. Planarian Anatomy and Biology""

""2.2. Planarian Morphological Plasticity """"2.3. The Cell Biology and Dynamics of Neoblasts ""; ""2.4. Neoblast Molecular Markers and First Lineage Descriptions""; ""3. CNS Regeneration and Complete Recovery of Neural Function in Planarians""; ""3.1. Planarian CNS: Structure and Regeneration ""; ""3.2. Genes Required for the Reconstruction of Neural Networks ""; ""3.3. Nou-Darake Restricts Brain Tissues in the Cephalic Region ""; ""3.4. miRNAs and Neural Regeneration and Repair ""; ""4. Pattern Formation during Planarian Regeneration ""; ""4.1. Pattern Formation and Development""

""4.2. The BMP and WNT/Î?-Catenin Pathways Direct Body Axis Establishment during Planarian Regeneration """"4.3. The BMP Pathway Is Essential For Establishing the DV Axis in Planarians ""; ""4.4. The WNT/β-Catenin Pathway Is Essential for Establishing the AP Axis in Planarians ""; ""4.5. Differential and Restricted Planarian WNT Domains ""; ""4.6. Planarians Represent a Unique Model for Patterning Studies ""; ""5. Regeneration, Tumor Formation and Cancer ""; ""Conclusion ""; ""Acknowledgments ""; ""References ""

""Mesenchymal Stem Cells in Tissue Regeneration and Organogenesis Using a Porcine Model """"Abstract ""; ""1. Introduction""; ""2. Sources of Porcine Mesenchymal Stem Cells ""; ""3. Isolation and In Vitro Characteristics of Porcine Mesenchymal Stem Cells ""; ""4. In Vitro Differentiation Potential of Porcine Mesenchymal Stem Cells ""; ""4.1. Osteogenic Potential ""; ""4.2. Adipogenic Potential ""; ""4.3. Chondrogenic Potential ""; ""4.4. Myogenic Potential ""; ""4.4.1. Smooth Muscle Cells ""; ""4.4.2. Myocytes/Cardiomyocytes ""; ""4.5. Angiogenic Potential ""; ""4.6. Hepatogenic Potential ""

""4.7. Epidermal Potential ""

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

1-61761-342-8