Vasculitis : from diagnosis to treatment / Roger M. Brown, editor.

Format:

Book

Contributor:

Brown, Roger M., editor.

Series:

Rheumatism and musculoskeletal disorders.

Rheumatism and Musculoskeletal Disorders

Language:

English

Subjects (All):

Vasculitis.

Physical Description:

1 online resource (290 pages)

Place of Publication:

New York : Nova Science Publishers, Inc., [2021]

Summary:

"Vasculitis refers to diseases that cause blood vessel walls to thicken and narrow, cutting off blood supply to tissues and organs. Vasculitis encapsulates several conditions, and the cause of vasculitis is often unknown. This book explores various forms of vasculitis and options for treatment. Chapter One includes a detailed description of giant cell arteritis, a form of vasculitis involving inflammation of the middle and large arteries, including the latest management strategies. Chapter Two concerns different types of vasculitis affecting the lungs, their signs and symptoms, treatment, and complications needed for diagnosis. Chapter Three deals with eosinophilic granulomatosis with polyangiitis, a multisystemic necrotizing vasculitis characterized by allergic rhinitis, asthma, and peripheral eosinophilia. Chapter Four describes the common pathophysiology and cardiovascular complications arising in different vasculidities. Chapter Five reviews the pathophysiology, epidemiology, diagnostic investigation, and treatment of infection etiologies of Herpesviridae associated with vasculitis. Chapter Six elucidates the impact of vasculitis on the gastrointestinal system. Chapter Seven explains hypocomplementic urticarial vasculitis syndrome, defined as presence of greater than six months of urticaria along with hypocomplementemia and multi-system manifestations such as recurrent abdominal pain, uveitis, arthralgia and glomerulonephritis. Chapter Eight explicates the use of biologics in treating rheumatology disorders, with rituximab being recommended in organ-threatening, refractory systemic lupus erythematosus. Lastly, Chapter Nine discusses the pathophysiology and adverse effects of adenoviral vector vaccinations for SARS-CoV-2 and the importance of identifying the true epidemiology of adverse outcomes regarding promoting increased acceptance of COVID-19 vaccinations, while stressing that despite the possibility of adverse outcomes, the benefits of vaccination outweigh the risks of remaining unvaccinated"-- Provided by publisher.

Contents:

Intro

Contents

Preface

Chapter 1

Giant Cell Arteritis

Abstract

Introduction

Epidemiology

Pathology and Pathophysiology

Signs and Symptoms

Investigations

Temporal Artery Biopsy

Ultrasonography (USG)

MRI

PET

Treatment

Methotrexate

Interleukin-Receptor Blocking Agents

Tocilizumab

Additional Comments on Treatment

New Treatment Developments

Conclusion

Disclaimer

References

Chapter 2

Pulmonary Complications of Vasculitis

Classification and Nomenclature

Prevalence

Pathophysiology

Pulmonary Vasculitis

Large-Vessel Vasculitis

5.1.2. Takayasu Arteritis

Medium-Vessel Vasculitis

Polyarteritis Nodosa

Kawasaki Disease

Small-Vessel Vasculitis

ANCA-Associated Vasculitis

Granulomatosis with Polyangiitis

Microscopic Polyangiitis

Eosinophilic Granulomatosis with Polyangiitis

Immune Complex Small Vessel Vasculitis

Anti-Glomerular Basement Membrane Antibody Disease

IgA Vasculitis

Cryoglobulinemic Vasculitis

Hypocomplimentemic Urticarial Vasculitis

Variable-Vessel Vasculitis

Behçet Disease

Vasculitis due to Systemic Disease and Other Causes

Necrotizing Sarcoid Granulomatosis

Systemic Lupus Erythematosus-Related Vasculitis

Rheumatoid Arthritis-Related Vasculitis

Coronavirus Disease 2019-Related Vasculitis

Drug-Induced Pulmonary Vasculitis

Chapter 3

History

Etiology

Immune Dysfunction

Genetic Factors

Drug-Related Factors

Eosinophil Mediated Tissue Injury

ANCA Mediated Tissue Injury

Histopathology

Clinical Presentation

Organ System Involvement.

Upper Respiratory Tract and Pulmonary Manifestations

Gastrointestinal Involvement

Skin Involvement

Renal Involvement

Cardiovascular Involvement

Neurologic Involvement

Musculoskeletal Involvement

Thromboembolic Disease

Lymphadenopathy

Initial Investigations

Post-Diagnostic Evaluation

Diagnosis

Prognosis

Chapter 4

Cardiovascular Complications of Vasculitis

Pathophysiology of Complications in Vasculitides

Large Vessel Vasculitis

Takayasu Arteritis

Medium Vessel Vasculitis

Small Vessel Vasculitis

Variable Vessel Vasculitis

Chapter 5

Cerebral Vasculitides Associated with Central Nervous System Herpesviridae Infection

Clinical and Imaging Manifestations of Herpes Virus Infection-Related Vasculopathy

Herpes Simplex Virus 1 and 2

Varicella Zoster Virus

Diagnosis of CNS Infection of Herpes Virus

Chapter 6

Gastrointestinal Complications of Vasculitis

Single-Organ Vasculitis

Vasculitis Associated with Systemic Disease

Diagnostic Evaluation

Treatment and Management

Chapter 7

Hypocomplementic Urticarial Vasculitis Syndrome

Pathophysiology.

Clinical Presentation

Cutaneous Manifestations

Extra-Cutaneous Manifestations

Joints

Pulmonary Manifestations

Renal Manifestations

Gastrointestinal Manifestations

Ocular Manifestations

Cardiovascular Manifestations

Neurologic Manifestations

Management

Chapter 8

Pulmonary Capillaritis in Systemic Lupus Erythematosus

Materials and Methods

Selection of Patients

Collection of Data

Review of Literature

Statistical Analyses

Results

Discussion

Acknowledgments

Chapter 9

Cerebral Venous Sinus Thrombosis as a Complication of COVID-19 Vaccination

Background

CVST Excluding COVID-19

Epidemiology of CVST during COVID-19

Epidemiology of CVST/VITT after COVID-19 Infection

Versus Vaccination

Risk Factors for VITT/CVST

SARS-CoV-2 and Human Immune Response

COVID-19 Vaccination and the Human Immune Response

Adverse Effects of Vaccination

Clinical Features of CVST

Spectrum of Thromboses after Vaccination

Management of VITT

Future Research

Index

Blank Page

Blank Page.

Notes:

Description based on print version record.

ISBN:

1-68507-324-7

OCLC:

44258771