Fundamentals of medical biotechnology / Rajneesh Prajapat.

Format:

Book

Author/Creator:

Prajapat, Rajneesh, author.

Series:

Recent Trends in Biotechnology

Language:

English

Subjects (All):

Medical technology.

Physical Description:

1 online resource (249 pages)

Place of Publication:

New York : Nova Science Publishers, [2021]

Summary:

"Biotechnology, an allied subject of biology, is also associated with its neighboring subject areas, such as: biochemistry, biophysics, biostatistics, pharmacology, cell biology, molecular biology, clinical biology, genomics and proteomics and nanotechnology, which makes this subject an advanced area in medical and health sciences. The exponential growth of the above fields in the past three decades, particularly information technology and biomedical technology and their myriad applications in medicine and health sciences, makes the field of biotechnology a potential front runner. The sophistication in biological techniques and methods makes biotechnological studies more precise, interesting, measurable and reproducible. Fundamentals of Medical Biotechnology is designed to cover all the areas of biotechnological advancement in cell biology, genetics, molecular biology, biochemistry, metabolism, microbiology, clinical pharmacology, immunology, biostatistics and bioinformatics. It helps students of biology, biotechnology, medical sciences and other health sciences to learn the advancement in the field of biomedicine and biotechnology. The book also covers the basics of diagnostic techniques in clinical biochemistry, specific to the technologies addressed in various chapters in the book, at both theoretical and application levels. The book focuses on why these techniques are useful in a clinical context and considers their potential uses, limitations and the ethical considerations that surround their use. This book is based on the recent development in the research dynamics of medical biotechnology, biochemistry and the progress in these fields. It also provides current reference material for students entering the field of medical and bioinformatics, academicians as well as research scientists. The book is a useful source of knowledge for students at senior secondary level, undergraduate and postgraduates in biotechnology and allied subjects, and MBBS / BDS level students looking for an accessible introduction of the subject"-- Provided by publisher.

Contents:

Intro

Contents

Preface

Chapter 1

Medical Biotechnology: An Introduction

Abstract

1. Introduction

2. MedicalBiotechnology: An Introduction

3. Recombinant DNA Technology

4. Genome Editing and Gene Therapy

5. Monoclonal Antibodies and Plantibodies

6. Vaccine Technology

7. In Silico Drug Designing

8. Human Genome Project

9. RNA Interference

10. Nano-Biotechnology and Nano-Medicine

11. Stem CellTherapy

12. Metamaterials

Conclusion

References

Chapter 2

Medical Diagnostics

1.1. What Is Medicine?

2. Medical Diagnosis: An Introduction

3. Diagnostic Process

3.1. The 'Diagnostic Process' Proceeds as Follows

4. Diagnosis vs. Prognosis

5. Diagnosis Test

5.1. RT-PCR for COVID-19 Diagnosis

5.2. AIDS Diagnosis by ELISA

5.2.1. Immunoglobulin (Ig)/Antibody

5.2.2. Antigen

5.3. Significance of Diagnostic Process

6. Phlebotomy

7. Computer Aided Diagnosis

Chapter 3

Research Methodology of Medical Science "In Silico Analysis of GDF15 Using Gynecoinformatics"

1. Research Methodology and Gyneco Informatics: An Introduction

2. Methods

2.2. Model Reputation

3. Results and Discussion

3.1. The Building of Protein Model

3.2. Model Reputation

3.3. Model Validation

Chapter 4

Nanomaterials: Synthesis, Characterization and Applications

2. Nanoscience and Nanotechnology: Definition

2.1. Characteristics of Nanomaterials

3. Classification of Nanomaterials

3.1. Dimensions of Nanoparticles

3.2. Morphology of Nanomaterials

3.3. Chemical Composition of Nanomaterials

4. Synthesis of Nanomaterials

4.1. Top-Down Approach

4.2. Bottom-Up Approach

5. Characterization of Nanomaterials.

5.1. Characterization of Nanomaterials

6. Applications of Nanomaterials

6.1. Nanoparticles in Cosmetics

6.2 Nanoparticles in Paints Formulation

6.3. Nanoparticles in the Ceramics Industry

6.4. Nanoparticles in the Textile Industry

7. Nanomaterials in Medical Science

7.1. Wound Dressings

7.2. Catheters

7.3. Bone Cement

7.4 Dental Materials

7.5. Bio-Diagnosis

Chapter 5

Recent Green Synthesis and Biological Applications of 4h-Pyrimidobenzothiazole Derivatives

2. Recent Green Synthetic Pathway

3. Biological Importance of Pyramidobenzothiazoles

Chapter 6

Synthesis of Privileged Biologically Active Scaffolds

2. Multicomponent Reactions

3. Review of Literature

4. Post-Modifications

Chapter 7

Endocrinology and Medical Biotechnology Advancement

1. Endocrine System: Introduction

2. Endocrine Glands in Human Body

3. Hypothalamus

3.1. Metabolic Effect of Hypothalamic Damage

4. Pituitary Gland

4.1. Malfunctioning of Anterior Pituitary

4.2. Pituitary Hormone Deficiency and Treatment

4.2.1. Growth Hormone Deficiency

4.3. Acromegaly

4.3.1. Production of Human Growth Hormone by Recombinant DNA Technology

4.3.2. The Recombinant DNA Technology for Production of Human GH (Figure 2) [6

7]

4.4. Gonadotropin Deficiency

4.5. TSH Deficiency

4.6. ACTH Deficiency

4.7. PRL Disorder

4.8. Malfunctioning of Posterior Pituitary/Neurohypophysis

4.9. ADH Deficiency

4.10. Diabetes Insipidus

4.11. Oxytocin

5. Thyroid Gland

5.1. Thyroid Disorders

5.1.1. Deficiency of Iodine

5.1.2. Hashimoto Disease

5.1.3. Hyperthyroidism

6. Parathyroid Gland

6.1. Parathyroid Disorders.

6.1.1. Disorders of Parathyroid

Hyperparathyroidism

Hypoparathyroidism

7. Thymus

7.1. Disorders of Thymus

7.1.1. Myasthenia Gravis

7.1.2. Pure Red Cell Aplasia

8. Pancreas

8.1. Islets of Langerhans

8.2. Glucagon

8.3. Insulin

8.4. Disorders of Pancreas

8.4.1. Diabetes Mellitus

8.4.2. Type 1 Diabetes

8.4.3. Type 2 Diabetes

8.5. Production of Human Insulin Using rDNA Technology

9. Adrenal Gland

9.1. Adrenal Cortex

9.1.1. Zona Glomerulosa (Outer Region)

9.2. Disorders of Adrenal Cortex

9.2.1. Hyperaldosteronism/CONN Syndrome

Zona Fasciculata (Middle Region)

9.2.2. Cushing Syndrome

9.2.3. Addison's Disease

Zona Reticularis (Inner Region)

9.3. Adrenal Medulla

9.4. Physiologic Effects of Medullary Hormones

10. Testis

10.1. Disorders of Reproductive Hormone Secretion

10.1.1. Hypogonadism

10.1.2. Gyneco Mastia

11. Ovaries

11.1. Disorders of Estrogen Secretion

11.1.1. Precocious Puberty

11.1.2. Delayed Puberty

FSH Production by rDNA Technology

Chapter 8

Assisted Reproductive Technologies: An Overview

1. ART: An Introduction

2. Advancement in ART

2.1. In-Vitro Fertilization

2.2. In-Vitro Maturation (IVM) of Eggs

2.3. Oocyte Retrieval

2.4. Gamete Intrafallopian Transfer (GIFT)

2.5. Zygote Intrafallopian Transfer (ZIFT)

2.6. Intracytoplasmic sperm Injection (ICSI)

2.7. Cryopreservation

2.8. Embryo Selection

2.9. Sperm Sorting

2.10. Cytoplasm Transfer

2.11. Intra Uterine Culture of Embryos

2.12. Artificial Uterus

2.13. Surrogacy

3. Risk Factors Associated with ART

4. IVF Success with Number of Embryos

5. Factors Affecting ART Success

Chapter 9

Anatomy and Histology: Pregnancy Induced Hypertensive Placentae

Abstract.

1. Hypertensive Placentae: Introduction

2. Materials and Methods

2.1. Morphological Study

2.2. Methods of Morphological Study

2.3. Number of Cotyledons in Placenta

2.4. Histological Study

Chapter 10

Medical Biotechnology Techniques and Biomedical Waste Management

2. Electrophoresis

2.1. Agarose

2.2. Polyacrylamide Gel Electrophoresis (PAGE)

2.3. Visualization of Protein Bands

2.4. Immuno-Electrophoresis

3. Isoelectric Focusing (IEF)

4. Two-Dimensional Gel Electrophoresis

5. ELISA Test

5.1. Indirect ELISA

6. Mass Spectrometry

7. Polymerase Chain Reaction (PCR)

8. Management of Biomedical Waste

Chapter 11

Medical Mathematics

1. Biostatistics: An Introduction

1.1. Types of Data

2. Representation of Data

2.1. Frequency Distribution Table

2.2. Bar Graphs

2.3. Histogram

2.4. Line Graph

3. Measures of Central Tendency

3.1. Mean

3.2. Median

3.3. Mode

4. Measures of Dispersion

4.1. Mean Deviation

4.2. Standard Deviation

4.3. Coefficient of Variance

4.4. Quartile Deviation

About the Editors

Index.

Notes:

Description based on print version record.

ISBN:

1-5361-9393-3

OCLC:

1240829030