Enterohemorrhagic Escherichia coli and other shiga toxin-producing E. coli / edited by Vanessa Sperandio and Carolyn J. Hovde.

Format:

Book

Contributor:

Sperandio, Vanessa, editor.

Hovde, Carolyn J., editor.

Language:

English

Subjects (All):

Escherichia coli infections.

Escherichia coli O157:H7.

Verocytotoxins.

Hemolytic-uremic syndrome.

Physical Description:

1 online resource (570 p.)

Place of Publication:

Washington, District of Columbia : ASM Press, 2015.

Language Note:

English

Summary:

Most Escherichia coli strains live harmlessly in the intestines of healthy humans and animals, but virulent strains-the enterohemorrhagic E. coli (EHEC) and certain Shiga toxin-producing E. coli (STEC)-cause life-threatening infections, with young children and the elderly most at risk. EHEC and STEC are easily transmitted through contaminated water or food and, more rarely, through contact between animals and people. Thus, controlling outbreaks of these pathogens is a concern for the infectious disease community and the food industry.Covering a diverse array of topics, including microbial pathogenesis, disease pathophysiology, food safety, genetic analysis, veterinary microbiology, epidemiology, and environmental microbiology, Enterohemorrhagic Escherichia coli and Other Shiga Toxin-Producing E. coli presents the most current, relevant research overview from a multidisciplinary, international group of expert authors concerned with tracking, deciphering, and dealing with the diseases caused by EHEC and STEC.Editors Vanessa Sperandio and Carolyn J. Hovde have updated and expanded the scope of the previous edition, Escherichia coli O157:H7 and Other Shiga Toxin-Producing E. coli Strains. Useful as a textbook for advanced courses in microbiology, food safety, infectious disease, or microbial pathogenesis, this new volume is also a valuable reference for research scientists, clinicians, health professionals, policy makers, and food safety professionals.

Contents:

""Cover ""; ""Half Title ""; ""Title Page ""; ""Copyright""; ""Contents""; ""Contributors""; ""Preface""; ""OVERVIEW ""; ""Chapter 1: Overview and Historical Perspectives""; ""HISTORY""; ""THE PRESENT""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""MICROBIOLOGY ""; ""Chapter 2: Taxonomy Meets Public Health: The Case of Shiga Toxin-Producing Escherichia coli""; ""PATHOTYPES AND TAXONOMY""; ""PATHOTYPES""; ""PHYLOGENY AND DISEASE""; ""TOXIN AND DISEASE""; ""Stx-ASSOCIATED BACTERIOPHAGE INSERTION""; ""TOXIN EXPRESSION AND Q GENES""; ""GENOMIC ISLANDS""; ""TAXONOMY AND PUBLIC HEALTH""

""ACKNOWLEDGMENTS""""CITATION""; ""REFERENCES""; ""Chapter 3: Shiga Toxin (Stx) Classification, Structure, and Function""; ""OVERVIEW""; ""TYPING AND NOMENCLATURE""; ""SHIGA TOXIN STRUCTURE""; ""Stx AND CELL BINDING""; ""RETROGRADE TRAFFICKING OF THE Stxs""; ""ACTIONS OF Stx IN TARGET CELLS""; ""Stx1a COMPARED TO Stx2a""; ""Stx ASSOCIATION WITH DISEASE""; ""SUMMARY""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""Chapter 4: Enterohemorrhagic Escherichia coli Genomics: Past, Present, and Future""; ""INTRODUCTION""; ""RESERVOIRS FOR HUMAN HEALTH""

""TYPING AND GENETIC ANALYSIS OF EHEC OUTBREAKS WITH PREGENOMIC METHODOLOGIES""""HISTORICAL VIEW OF EHEC/STEC GENOMICS""; ""GENOMICS-GUIDED EXAMINATION OF PATHOGENESIS""; ""PUBLIC HEALTH VIEW- WHAT ARE THE NEXT STEPS?""; ""CONCLUSION""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""PATHOGENESIS""; ""Chapter 5: Role of Shiga/Vero Toxins in Pathogenesis""; ""ACTIVITIES OF Stx AND LPS IN RENAL DISEASE""; ""ACTIVITIES OF Stx IN CNS DISEASE""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""

""Chapter 6: The Locus of Enterocyte Effacement and Associated Virulence Factors of Enterohemorrhagic Escherichia coli """"INTRODUCTION""; ""THE LOCUS OF ENTEROCYTE EFFACEMENT""; ""MODULATION OF INNATE IMMUNITY""; ""FUTURE PERSPECTIVES""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""Chapter 7: Enterohemorrhagic Escherichia coli Adhesins""; ""INTRODUCTION""; ""LOCUS OF ENTEROCYTE EFFACEMENT""; ""CLOSING REMARKS""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""Chapter 8: Animal Models of Enterohemorrhagic Escherichia coli Infection""; ""INTRODUCTION""

""OBSERVATIONS FROM HUMAN OUTBREAKS""""HISTORICAL PERSPECTIVE ON ANIMAL MODELS OF EHEC-MEDIATED DISEASE""; ""ROLE OF THE HOST IN MODULATING EHEC VIRULENCE""; ""CONCLUSIONS""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""; ""Chapter 9: Enterohemorrhagic Escherichia coli Virulence Gene Regulation""; ""ACID TOLERANCE""; ""MOTILITY""; ""CONTINUING THE INTESTINAL JOURNEY""; ""T3SS EXPRESSION AND ATTACHMENT""; ""INJECTION OF EFFECTORS""; ""TOXIN EXPRESSION AND PHAGE INDUCTION""; ""A REGULATED INFECTION CONTINUUM""; ""CONCLUSIONS""; ""ACKNOWLEDGMENTS""; ""CITATION""; ""REFERENCES""

""INCIDENCE, EPIDEMIOLOGY, AND ECOLOGY""

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

1-55581-879-X