The hepatitis E virus : pigs might fly / Harry Dalton.

Format:

Book

Author/Creator:

Dalton, H. R. (Harry Richard), author.

Language:

English

Subjects (All):

Hepatitis.

Genre:

Libros electrónicos.

Physical Description:

1 online resource (viii, 328 pages) : illustrations

Edition:

1st ed.

Place of Publication:

Newcastle upon Tyne, England : Cambridge Scholars Publishing, [2019]

Summary:

This volume is an account of scientific discovery related to the hepatitis E virus (HEV). HEV was first identified in Afghanistan in 1982 by a remarkably courageous act of self-experimentation by a Russian scientist. Following this, it was found that, in some developing countries in Asia and Africa, HEV was the cause of enormous outbreaks of hepatitis spread by infected drinking water, with a 25% death rate in pregnant women. For many years, HEV was thought not to be an issue in high-income countries and was only seen in travellers returning from high risk areas: it was considered a "back-packers'" disease. We now know that this was hopelessly wrong as HEV is very common in developed countries, with currently over 2 million infections per year in Europe. Here, HEV is found in pigs and spread mainly via consumption of contaminated pork meat. There has been a major increase in cases of HEV in many developed countries, including patients who have suffered liver failure, some of whom have died. We now know that HEV can also cause severe damage to the nervous system.This book describes an English doctor's contribution to the discovery of the impact of HEV in humans. Recent cases in the UK appear to have originated from pigs in Continental Europe and HEV was, as a consequence, dubbed by the international press as the 'Brexit Virus'; perhaps an early leaving present from our friends in the EU. Accessible to lay readers, the text includes case histories and stories from a health service increasingly under pressure and given context by examples of medical discoveries from the past. The role of the meat production industry, including questionable on-going high-risk virological practices, is put under the spotlight, leading to inevitable comparisons with the BSE crisis of the 1980s. HEV continues to exact a heavy toll in some low-income countries, most

notably with multiple large outbreaks in African refugee camps. Despite the best efforts of organisations such as Médecins Sans Frontières, each year, pregnant women continue to die by the score. This is particularly poignant as these deaths may be avoidable, as there is a safe and effective vaccine. However, the HEV vaccine is only licensed for use in China, and, so far, efforts to introduce it to Africa have hit a brick wall of politics and red tape.

Contents:

Intro

Dedication

Epigraph

Table of Contents

List of Illustrations

Chapter One

Chapter Two

Chapter Three

Chapter Four

Chapter Five

Chapter Six

Chapter Seven

Chapter Eight

Chapter Nine

Chapter Ten

Chapter Eleven

Chapter Twelve

Chapter Thirteen

Chapter Fourteen

Chapter Fifteen

Chapter Sixteen

Chapter Seventeen

Chapter Eighteen

Chapter Nineteen

Chapter Twenty

Chapter Twenty-one

Chapter Twenty-two

Chapter Twenty-three

Chapter Twenty-four

Chapter Twenty-five

Chapter Twenty-six

Chapter Twenty-seven

Chapter Twenty-eight

Chapter Twenty-nine

Chapter Thirty

Chapter Thirty-one

Chapter Thirty-two

Chapter Thirty-three

Chapter Thirty-four

Chapter Thirty-five

Chapter Thirty-six

Chapter Thirty-seven

Chapter Thirty-eight

Chapter Thirty-nine

Chapter Forty

Chapter Forty-one

Chapter Forty-two

Chapter Forty-three

Chapter Forty-four

Chapter Forty-five

Chapter Forty-six

Chapter Forty-seven

Chapter Forty-eight

Chapter Forty-nine

Chapter Fifty

Chapter Fifty-one

Chapter Fifty-two

Chapter Fifty-three

Chapter Fifty-four

Chapter Fifty-five

Chapter Fifty-six

Chapter Fifty-seven

Chapter Fifty-eight

Chapter Fifty-nine

Chapter Sixty

Chapter Sixty-one

Chapter Sixty-two

Appendix

Acknowledgements

Index

Lord Byron.

Notes:

Description based on print version record.

Description based on publisher supplied metadata and other sources.

ISBN:

1-5275-3044-2

OCLC:

1089125696