Inorganic biomaterials : structure, properties and applications / Xiang Zhang, editor.

Format:

Book

Contributor:

Zhang, Xiang, editor.

Language:

English

Subjects (All):

Biomedical materials.

Inorganic polymers.

Physical Description:

1 online resource (256 p.)

Place of Publication:

Shropshire, England : Smithers Rapra, 2014.

Language Note:

English

Summary:

This book provides a practical guide to the use and applications of inorganic biomaterials. It begins by introducing the concept of inorganic biomaterials, which includes bioceramics and bioglass. This concept is further extended to hybrid biomaterials consisting of inorganic and organic materials to mimic natural biomaterials. The book goes on to provide the reader with information on biocompatibility, bioactivity and bioresorbability. The concept of the latter is important because of the increasing role resorbable biomaterials are playing in implant applications. The book also introduces a n

Contents:

9781909030398_front cover; Preface; Contributors; Contents; Acknowledgments; 1 Inorganic Biomaterials Science and Engineering ; 1.1 Materials Chemistry and Physics; 1.2 Nano/Microstructure; 1.3 New Concept of Surface and Interfaces; 1.4 Hybrid Composites; 1.5 Materials and Processing Technology; 2 Biocompatibility, Bioactivity and Bioresorbability; 2.1 Biocompatibility; 2.2 Interaction of Artificial Biomaterials with Biological Systems; 2.2.1 Bioactive Ceramics; 2.2.2 Bioresorbable Ceramics; 2.2.3 Nonresorbable Ceramics; 2.3 Fabrication Strategies

2.4 Biological Evaluation of the Biocompatibility of Bioceramics2.4.1 Assessment of Cytotoxicity; 2.4.2 Genotoxicity; 2.4.3 Haemocompatibility; 2.4.4 In Vivo Test; 2.5 Case Study; 2.5.1 Composite Scaffold for Bone Tissue Engineering; 2.5.2 Injectable and Degradable Bioceramics for Bone Repair; 3 Inorganic Biomaterials Characterisation; 3.1 Introduction; 3.2 Raw Materials Characterisation; 3.2.1 Introduction; 3.2.2 What are Bulk and Surface Properties?; 3.2.3 Bulk Characterisation of Biomaterials; 3.2.3.1 Transmission Electron Microscopy; 3.2.3.2 X-ray Diffraction Spectroscopy

3.2.3.3 Fourier-Transform Infrared Spectroscopy3.2.3.4 Dynamic Light Scattering; 3.2.3.5 Mercury Intrusion Porosimetry; 3.2.3.6 X-ray Computed Tomography; 3.2.4 Surface Characterisation of Biomaterials; 3.2.4.1 X-ray Photoelectron Spectroscopy; 3.2.4.2 Secondary Ion Mass Spectrometry; 3.2.4.3 Optical Microscopy and Confocal Microscopy; 3.2.4.4 Scanning Electron Microscopy; 3.2.4.5 Contact Angle Measurement; 3.2.5 Mechanical Characterisation of Biomaterials; 3.2.5.1 Introduction; 3.2.5.2 Tensile and Shear Properties; 3.2.5.3 Time-dependant Properties

3.2.6 Cytotoxicity Testing of Inorganic Biomaterials3.2.6.1 Genotoxicity, Mutagenicity and Carcinogenicity Testing ofInorganic Biomaterials; 3.2.6.2 Other Useful In Vitro Assessment Tests Related to InorganicBiomaterials; 3.2.6.3 Summary; 3.3 In Vivo Assessment; 3.3.1 Introduction; 3.3.2 Properties Assessed during In Vivo Tests; 3.3.2.1 Sensitisation, Irritation and Intracutaneous Reactivity; 3.3.2.2 Systemic Toxicity; 3.3.2.3 Genotoxicity; 3.3.2.4 Implantation; 3.3.2.5 Haemocompatibility; 3.3.2.6 Carcinogenicity; 3.3.2.7 Reproductive and Developmental Toxicity; 3.3.2.8 Biodegradation

3.3.3 Immune Responses3.4 Case Studies; 3.4.1 Case Study 1; 3.4.2 Case Study 2; 4 Biomaterials Shortand Long-term Degradation; 4.1 Chemical and Physical Degradation; 4.1.1 Polymer Degradation; 4.1.1.1 Structure and Properties of Lactic Acid- and Glycolic Acid-basedPolymers; 4.1.1.2 Timescale of Polymer Degradation; 4.1.1.3 Mechanism of Polymer Degradation; 4.1.2 Bioceramic and Hybrid Biomaterials Degradation; 4.1.2.1 Calcium Phosphate Ceramics; 4.1.2.2 Degradable Hybrid Polymer Composites; 4.1.3 Hybrid Biomaterials in Clinic; 4.1.3.1 Successful Behaviour of Hybrid Biomaterials in Clinic

4.1.3.2 Unpredictable Behaviour of Hybrid Biomaterials in Clinic

Notes:

Includes index.

Description based on online resource; title from PDF title page (ebrary, viewed August 30, 2014).

ISBN:

1-909030-41-4