Leprosy : epidemiology, treatment strategies and current challenges in research / Roger S. Kopp, editor.

Format:

Book

Contributor:

Kopp, Roger S., editor.

Series:

Allergies and infectious diseases.

Allergies and Infectious Diseases

Language:

English

Subjects (All):

Leprosy--Congresses.

Leprosy.

Leprosy--Prevention.

Leprosy--Treatment.

Physical Description:

1 online resource (116 p.)

Place of Publication:

New York, New York : Nova Science Publishers, Inc., 2014.

Language Note:

English

Summary:

Leprosy is a chronic granulomatous infectious disease that affects the skin and peripheral nerves; its causative agent is the obligate intracellular bacillus Mycobacterium leprae. The etiological diagnosis of the disease in its paucibacillary (PB) form still needs to be improved, because the bacillus is not yet cultivable. This book discusses the current challenges in the research of leprosy, as well as the epidemiology and treatment strategies available.

Contents:

""LEPROSY: EPIDEMIOLOGY, TREATMENT STRATEGIES AND CURRENT CHALLENGES IN RESEARCH""; ""LEPROSY: EPIDEMIOLOGY, TREATMENT STRATEGIES AND CURRENT CHALLENGES IN RESEARCH""; ""Library of Congress Cataloging-in-Publication Data""; ""Contents""; ""Preface""; ""Chapter 1: Leprosy: From Clinical Diagnosis to Benchwork""; ""Abstract""; ""PCR with Primers for MntH (ML2098) Gene Amplification Sensitively and Specifically Identifies M. Leprae in Human Samples""; ""References""; ""Leprosy and Thromboembolic Phenomena""; ""References""; ""Genetic Markers on Leprosy""

""Association of the Solute Carrier Family 11 Member 1 Gene (SLC11A1/NRAMP1) polymorphisms with Susceptibility to Leprosy""""References""; ""Genetic Polymorphisms of Innate and Adaptive Immune Response and Susceptibility to Leprosy""; ""Conclusion""; ""Acknowledgments""; ""References""; ""Chapter 2: In Vivo and In Vitro Evidence on the Relationship between Antiphospholipid Antibodies and Leprosy""; ""Abstract""; ""Introduction""; ""Prevalence of aPL in Leprosy""; ""Specificity of aPL in Leprosy Patients""; ""Do aPL Positive Leprosy Patients Share Páthogenic Mechanisms with APS Patients?""

""In Vivo Studies Linking aPL with Leprosy""""Conclusion""; ""References""; ""Chapter 3: Leprosy and Pregnancy: A Epidemiological and Social Study in the Pará State, North of Brazil""; ""Abstract""; ""Introduction""; ""Concept and Etiology""; ""Classification � Clinic � Reactions""; ""Treatment and Prophylactic Actions""; ""Surveillance of Leprosy""; ""Leprosy and Pregnancy""; ""References""; ""Chapter 4: The Potential of Antimicrobial Peptide Inhibitors (APIs) and Elicitors (APEs) in Leprosy Treatment""; ""Abstract""; ""Introduction""; ""Side Effects in the Traditional""

""Treatment of Leprosy""""The Role of Antimicrobial Peptides in Leprosy""; ""Role of Defensins""; ""Role of Hepcidin""; ""Role of Cathelicidin LL-37""; ""Antimicrobial Peptide Inhibitors""; ""As Potential Treatment of Leprosy""; ""Antimicrobial Peptide Elicitors""; ""As Potential Treatment of Leprosy""; ""Conclusion""; ""Acknowledgments""; ""References""; ""Index""

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

1-63321-671-3

OCLC:

890934410