Allium sativum : chemical constituents, medicinal uses and health benefits / Abel Haynes, Editor.

Format:

Book

Contributor:

Haynes, Abel, editor.

Series:

Plant science research and practices.

Plant Science Research and Practices

Language:

English

Subjects (All):

Garlic--Therapeutic use.

Garlic.

Garlic--Health aspects.

Garlic--Composition.

Physical Description:

1 online resource (111 p.)

Place of Publication:

New York : Nova Publishers, 2016.

Language Note:

English

Summary:

The use of Allium sativum (garlic) for medicinal purposes has origin in antiquity and is still included in the traditional medicine of many cultures. Oral tradition and recorded history show that garlic is one of the earliest examples of plants used extensively since the existence of man. Historically, there has been great interest in the role and potential benefits of garlic in the management of diseases and maintenance of health. This book provides research on the chemical constituents, medicinal uses and health benefits of Allium sativum. The first chapter provides a historical perspective and folkloric applications of garlic in ancient cultures, the supposed role and benefits perceived/claimed to have played in health and disease and the substantive validation made so far by modern science. The next chapter provides a comparative review of Allium sativum extract and bioactive constituents. Chapter three reviews recent progresses in facilitating the in situ generated allicin methodology and its possible medicinal applications. Chapter four evaluates the antimicrobial activity, in vitro, of fresh Allium sativum Liliaceae against Staphylococcus aureus (Sa) and Escherichia coli (E. coli). The last chapter's main objective is the development of a preliminary mechanical system for the culture of garlic.

Contents:

ALLIUM SATIVUM CHEMICAL CONSTITUENTS, MEDICINAL USES AND HEALTH BENEFITS ; ALLIUM SATIVUM CHEMICAL CONSTITUENTS, MEDICINAL USES AND HEALTH BENEFITS ; CONTENTS ; PREFACE ; Chapter 1 HISTORICAL PERSPECTIVE AND FOLKLORIC USE OF GARLIC ; ABSTRACT ; INTRODUCTION ; ORAL TRADITION AND RECORDED HISTORY INFORMATION ON THE USE OF GARLIC ; Ancient Egypt and Biblical Records ; Ancient Greece ; Ancient Rome ; Ancient Asia ; Middle Ages ; The Renaissance and Prior to Contemporary Times ; FOLKLORIC CLAIMS AND CONTEMPORARY SCIENCE ON THE MEDICINAL USE OF GARLIC: NEED FOR GLOBAL HARMONIZATION

Garlic and Cardiovascular Disease Garlic and Cancer ; Need for Harmonization of Folkloric and Contemporary Health Claims; REFERENCES ; Chapter 2 MEDICINAL USE AND HEALTH BENEFITS OF ALLIUM SATIVUM: A COMPARATIVE REVIEW OF THE WHOLE EXTRACT VS BIOACTIVE CONSTITUENTS ; ABSTRACT ; INTRODUCTION; GARLIC PRODUCT PROCESSES; THE PRIMARY SULPHUR-CONTAINING CONSTITUENTS OF GARLIC AND THEIR CHEMISTRY; HEALTH BENEFITS OF GARLIC ; ANTI-CANCER HEALTH EFFECT-MECHANISM OF ACTION ; Bioactive Constituents and Anti-Cancer Health Effects ; ANTIOXIDANT HEALTH EFFECTS OF GARLIC: MECHANISM OF ACTION

Scavenging ROS, Inhibiting LDL Oxidation and Lipid Peroxide Formation Enhancement of Endogenous Cellular Antioxidant Defences ; Enhancement of Enzymatic and Non-Enzymatic Antioxidants ; Bioactive Constitulents: Anti-Oxidant Health Effects ; EFFECTS OF GARLIC ON CARDIOVASCULAR AND CEREBROVASCULAR DISEASES; Bioactive Constituents: Cardiovascular and Cerebrovascular Health Effects ; ANTI-AGING EFFECTS OF GARLIC ; HYPOGLYCAEMIC EFFECTS OF GARLIC ; EFFECTS OF GARLIC ON THE IMMUNE SYSTEM ; Anti-Allergic Effect ; ANTIBACTERICIDAL EFFECTS OF GARLIC ; Garlic and Helicobacter Pylori

Food Preservation CHEMO- AND RADIOPROTECTIVE EFFECTS OF GARLIC ; SAFETY AND TOXIC EFFECTS OF GARLIC ; REFERENCES ; Chapter 3 MEDICINAL APPLICATIONS OF IN SITU GENERATED ALLICIN ; ABSTRACT; INTRODUCTION ; PREPARATIONS OF ALLIIN AND ITS ANALOGS ; PREPARATIONS OF ALLIINASE ; Purification of Alliinase from Fresh Garlic Cloves ; Preparation of Alliinase by Recombinant Protein Expresion ; GENERATION OF ALLICIN IN SITU; Site-Directed Allicin Generation In Situ ; Preparation of Alliinase-Antibody Conjugation ; 4.1.2. Method of Administration of Alliinase and Alliin In Vivo

ANTI-CANCER ACTIVITY OF IN SITU ALLICIN ANTIMICROBIAL ACTIVITY OF IN SITU ALLICIN ; CONCLUDING COMMENTS AND FUTURE RESEARCH ; ACKNOWLEDGMENTS ; REFERENCES; Chapter 4 EVALUATION OF THE ANTIMICROBIAL ACTIVITY OF THE FRESH ALLIUM SATIVUM LILIACEAE (GARLIC) ; ABSTRACT ; INTRODUCTION ; MATERIAL AND METHOD ; Vegetable Material ; Preparation of the Microbial Inoculums ; Preparation of the Culture Medium ; Experimental Method - Agar Diffusion Test ; Data Analysis ; RESULTS; Evaluation of Allium sativum, in natura, by the Agar Diffusion Method ; DISCUSSION ; CONCLUSION ; REFERENCES

Chapter 5 PRODUCT DEVELOPMENT: MECHANIZED SYSTEM FOR CULTURE OF GARLIC (ALLIUM SATIVUM L.)

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

1-63484-265-0