Photodynamic therapy mediated by fullerenes and their derivatives / Felipe F. Sperandio ... [et al.].

Format:

Book

Author/Creator:

Sperandio, Felipe F., author.

Contributor:

Sperandio, Felipe F.

Series:

Biomedical and nanomedical technologies.

Biomedical & nanomedical technologies

Language:

English

Subjects (All):

Photochemotherapy.

Fullerenes.

Medical Subjects:

Photochemotherapy.

Fullerenes.

Physical Description:

1 online resource (62 p.)

Place of Publication:

New York, N.Y. : ASME ; New York, N.Y. (222 East 46th Street, New York, NY 10017) : Momentum Press, 2013.

Language Note:

English

Summary:

The fullerene molecule with its unique structure of 60 carbon atoms arranged in a soccer ball structure is a molecule of great potential for a variety of applications and has drawn attention of lots of physicists, chemists and engineers. Recently, these nanostructures have also been studied for their biological activities with a view towards using them for biomedical applications. One of the possible therapies for which fullerenes may have a real medical application is the light based therapy called photodynamic therapy (PDT), which is a non-surgical, minimally invasive approach that has been used in the treatment of solid tumors and many non-malignant diseases.

Contents:

1. Introduction to fullerenes and PDT

1.1 Introduction to fullerenes and PDT

1.2 Fullerenes as PS

2. Synthesis of fullerene derivatives

2.1 Synthesis of monocationic and polycationic fullerene derivative examples

2.2 Synthesis of hexaanionic fullerene derivatives

2.3 Synthesis of chromophore-linked fullerene derivatives

3. Photochemistry and photophysics of fullerenyl molecular micelle and chromophore-fullerene conjugates

4. Antimicrobial PDT mediated by fullerenes and their derivatives

4.1. Antimicrobial PDT mediated by fullerenes and their derivatives

4.2 Fullerenes interaction with cell membrane

4.3 Anti-bacterial PDT with fullerenes and derivatives

4.4 Anti-fungal PDT with fullerenes and derivatives

4.5 Anti-viral PDT with fullerenes and derivatives

4.6 Toxicity studies of fullerenes and derivatives

5. Anti-cancer PDT

5.1 Photodynamic therapy of cancer cells

6. In vivo PDT studies with fullerenes

6.1 In vivo applications-PDT for infections and tumors

7. Conclusions & executive summary

7.1 Conclusion & future and perspectives

7.2 Executive summary

References.

Notes:

"ASME order no. 860083."

Includes bibliographical references (p. 39-51).

Title from PDF t.p. (viewed on January 25, 2013).

ISBN:

0-7918-6008-6

1-283-94833-8

1-60650-416-9

OCLC:

826853653