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Tumor necrosis factor : structure, enzyme regulation and role in health and disease / Agueda Escarra, editor.
EBSCOhost Academic eBook Collection (North America) Available online
EBSCOhost Academic eBook Collection (North America)- Format:
- Book
- Series:
- Cell Biology Research Progress
- Language:
- English
- Subjects (All):
- Tumor necrosis factor.
- Chronic diseases.
- Physical Description:
- 1 online resource (154 p.)
- Place of Publication:
- Hauppauge, NY : Nova Science Publishers, Inc., 2013.
- Language Note:
- English
- Summary:
- Tumor necrosis factor-alpha (TNF-a) is a potent pro-inflammatory cytokine exerting pleiotropic effects on various cell types and plays a critical role in the pathogenesis of chronic inflammatory diseases. In this book, the authors discuss the structure, enzyme regulation and role in health and disease of TNF. Topics include TNF-a related to signal pathways and neuronal diseases; the role of TNF-a in rheumatoid arthritis and autoimmunity; the presence of 308-A TNF allele and its association with the clinical parameters of myelodysplastic syndromes; the significance of TNF in the immune response against tuberculosis; and TNF-a signaling and cathespin B.
- Notes:
- Description based upon print version of record.
- Includes bibliographical references and index.
- Description based on print version record and CIP data provided by publisher.
- ISBN:
- 1-62417-722-0
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