Once we were hunters : a study of the evolution of vascular disease / editor, Gianni Belcaro.

Format:

Book

Contributor:

Belcaro, G. (Gianni)

Language:

English

Subjects (All):

Atherosclerosis.

Coronary heart disease.

Human evolution.

Physical Description:

1 online resource (139 p.)

Place of Publication:

London : Imperial College Press, c2001.

Language Note:

English

Summary:

We emerged after millions of years of evolution, first in the rainforest and then in the dry savanna bush. This nomadic way of life was characterised by seasonal and geographical variation of food; scarcity, particularly of high-energy food containing fats and sugar; and walking as the main form of exercise, with sudden bursts of energy either to catch prey or to avoid becoming prey. Society was organised into structured, small-groups, contact among whom was very limited under normal conditions.After this 25 million-year period of evolution, however, we have now entered a period of de-evolutio

Contents:

PREFACE; ACKNOWLEDGEMENTS; CONTENTS; INTRODUCTION; A. The Acid that Eats Anything; B. De-Evolution; C. Baby, We Were Born to Run; D. Once We Were Hunters; E. Save Your Life; PART I EVOLUTION AND CARDIOVASCULAR DISEASES IN A NUTSHELL; Chapter 1 LUCY IN THE SKY; Location: Awash, Ethiopia; Late Summer 1984 August 23rd; And Now?; We Still are Hunters; Chapter 2 EVOLUTION; Chapter 3 THE HUNTING SEASON; Chapter 4 ATHERO-PEOPLE; Accumulation, Release and Use of Stores; Chapter 5 ALL SELECTION THAT REALLY MATTERS HAPPENS BEFORE REPRODUCTION; Chapter 6 OUR POPULATION NOW; No Selection Any More?

The Concept of De-EvolutionChapter 7 VASCULAR EPIDEMIOLOGY, ITS MEANING AND WHAT POPULATION STUDIES TELL US; Chapter 8 RIFT VALLEY; November 1946 and After 50 Years; Harmony. The Hunter Back Home; Lessons from the ""doctor"":; Chapter 9 A THEORY TO BE DEMONSTRATED; Chapter 10 EVOLUTION, NATURAL SELECTION AND ATHEROSCLEROSIS. WE STILL ARE WHAT WE HAVE BEEN SELECTED FOR; Chapter 11 NOW WHAT?; Chapter 12 KNOWING OUR DESTINY; Chapter 13 CONCLUSIONS?

Chapter 14 ATHEROSCLEROSIS AS A RESPONSE TO THE ACCUMULATION OF UPOPROTEINS IN THE ARTERIAL WALL. THE RESPONSE-TO-RETENTION HYPOTHESIS IN EARLY ATHEROGENESISWhere are the Lesions?; The Second Process at the Basis of Atherogenesis is Considered to be Lipoprotein Oxidation; Retention of Lipoproteins in the Arterial Wall is the Key Event; Consequences of Retention; Not All Individuals Have the Same Problems; Drugs or Others?; Conclusions; PART II EVOLUTION AND MEDICINE; Chapter 15 EVOLUTIONARY MEDICINE; A. Introduction; Evolution Takes Time

B. Original Selection and Evolution, and Discrepancy between the Evolutionary Shape of Humans and the Present Human FigureC. Common Objections to Natural-Selection-Based Theories in Medicine; D. The Evolutionary Design (ED) and the Present Environmental Conditions (EC); E. Our Life; Us and Today; Reference; F. Evolution and Our Story Now. And Cosmically Speaking: Does It Matter?; The Hitch Hiker Guide to the Galaxy; G. The Evolutionary Ladder; Chapter 16 SAVUTI, BOTSWANA. THE BEGINNING AND THE END OF THE WORLD; A. Aggressivity; B. The Symbolic Hunting Response; C. Diet and Vascular Disease

We Have Been Built for a Life with a Little Amount of FoodD. Super-Stimuli; E. Conditioning; The Desire for Today and Tomorrow; F. Voluntary Food Restrictions; G. Exercise and Being Lazy; H. Contacts (Well, Actually No Contacts); Conclusions; Contacts with Other Humans; I. The Problem of Food Biodiversity; A More Complete Picture; J. Immunology and Contacts; Mbarara in Uganda, February 1996; Conclusions; K. High Blood Pressure; Forced Selection; Chapter 17 CARDIOVASCULAR DISEASE AND EVOLUTION; A. How Do We Use these Observations?; B. Individual and Group Selection; C. Evolution - Bits

Biological, Evolutionary-Resulting Accumulation of Food in the Body

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

9781848166837

1848166834