Membrane structure in disease and drug therapy / edited by Guido Zimmer.

Format:

Book

Contributor:

Zimmer, G. (Guido), 1932-

Language:

English

Subjects (All):

Membrane disorders.

Cell membranes.

Drugs--Physiological transport.

Drugs.

Protein binding.

Physical Description:

1 online resource (552 p.)

Place of Publication:

New York : Marcel Dekker, c2000.

Language Note:

English

Summary:

This study asserts that cellular and intracellular membranes are active in every aspect of the body's physiology and pathophysiology. It compares secondary through to quaternary structures and protein sequences and gauges their influence on health, disease and drug therapy. The book highlights the importance of correlations, homologies and categorizing multifunctionality by domain and complex.

Contents:

Preface; Contents; Contributors; Introduction; Antibacterial and Hemolytic Activity of Amphipathic Helical Peptides; Bacterial Membrane as a Target for a Novel Class of Diastereomers of Cytolytic Peptides; Bee Venom Toxicity; Polymyxins; Environmental Effects on Skin Lipids and Impairment of Barrier Function; Oxidative Stress and Loose Coupling/Uncoupling; Uncouplers of Oxidative Phosphorylation; Tetraether Lipid Liposomes; Transfection of Eukaryotic Cells with Bipolar Cationic Derivatives of Tetraether Lipid; Cholera Toxin Conformational Changes Associated with Changes in Membrane Structure

Parasite Mitochondrial Membrane Functions as Targets for Chemotherapy Hepatic Cell Function in Liver Fluke Infection; Lipopolysaccharide; Effect of Cholestasis on Biomembranes; 3,5-Diiodothyronine Binds to Subunit Va of Cytochrome c Oxidase; Regulation of Glucose Transport by Insulin in Muscle and Fat Cells; Glucose-6-Phosphatase; Alzheimer's Amyloid ß-Peptide- Associated Oxidative Stress; Membrane Orientation of the Alzheimer's Disease-Associated Presenilins; Membrane Structure Analysis in Apoptotic Processes of Leukemic Blasts and Leukemia-Derived Cell Lines*

Use of Monoclonal Antibodies in Cloning and Identification of Membrane Antigens Polycystins; Action of ß-Agonists Compared to Cromoglycate on Mononuclear Cell Membranes; Cystic Fibrosis Transmembrane Conductance Regulator; Role of Ca2 -Independent Lysosomal Phospholipase A2 in Turnover of Lung Surfactant Phospholipids; Role of Sodium Pump in Disease; Index

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-135-54916-8

0-429-22222-X

1-135-54917-6

9786610146291

0-585-39352-4

1-280-14629-X

0-203-91005-2

9780429222221

OCLC:

71335398