L-arginine : structure, dietary sources and beneficial effects / Benjamin L. Soto, editor.

Format:

Book

Contributor:

Soto, Benjamin L., editor.

Series:

Biochemistry research trends series.

Biochemistry Research Trends

Language:

English

Subjects (All):

Arginine--Physiological effect.

Arginine.

Arginine--Metabolism.

Physical Description:

1 online resource (197 p.)

Place of Publication:

New York : Nova Publishers, 2016.

Summary:

Arginine is one of the amino acids with multiple metabolic pathways. Apart from its role in the composition of proteins, it is the biosynthetic precursor of nitric oxide, creatine, agmatine, proline, homoarginine and polyamines. In chapter One of this book, the reasons for and the possible advantages and disadvantages of nutritional arginine supplementation are critically discussed in the light of established biochemical results. Chapter Two summarizes the position and importance of the L-arginine in nitric oxide homeostasis, disbalance of which can be one of the causes of many acute and chronic diseases. Chapter Three provides a brief overview of L-arginine and cardiometabolic health. Chapter Four discusses the use of novel synthetic biodegradable arginine-rich implantable biomaterials and devices for human body repair and reconstruction. Chapter Five reviews beneficial effects of L-arginine supplementation in controlling blood pressure. Chapter Six reviews the recent information about the advantages of using L-Arginine as a dietary supplement to improve reproductive function in certain female domestic animals, such as the ewe, sow, and mare, as well as in female rats and humans.

Contents:

L-ARGININE: STRUCTURE, DIETARY SOURCES AND BENEFICIAL EFFECTS; L-ARGININE: STRUCTURE, DIETARY SOURCES AND BENEFICIAL EFFECTS; Library of Congress Cataloging-in-Publication Data; CONTENTS; PREFACE; Chapter 1: IS ARGININE TRULY A "MIRACLE MOLECULE"?: A CRITICAL EVALUATION OF NUTRITIONAL ARGININE SUPPLEMENTATION FROM A BIOCHEMICAL POINT OF VIEW; ABSTRACT; ABBREVIATIONS; INTRODUCTION; Arginine, the Multifaceted Amino Acid; 2. ARGININE AVAILABILITY UNDER NORMAL CONDITIONS; 2.1. Arginine Absorption and Transport; 2.2. De novo Arginine Synthesis; 3. ARGININE PATHWAYS IN MAMMALIAN CELLS

3.1. Nitric Oxide Synthesis3.2. The Arginase Pathway; 3.3. Synthesis of Creatine from Arginine; 3.4. Homoarginine Synthesis from L-arginine; 3.5. Arginine Decarboxylation Yields Agmatine; 3.6. Arginine Metabolism and Post-Translational Modifications; 3.6.1. Methylated Arginine Synthesis; Protein Arginine Methylation Reactions; 3.6.2. Peptidyl Citrulline Formation by Protein Arginine Deiminase; 4. ARGININE SUPPLEMENTATION IN VARIOUS DISEASES; 4.1. Arginine Supplementation and the Cardiovascular System; 4.2. Homoarginine and Cardiovascular Disorders

4.3. Arginine Supplementation and the Respiratory System4.4. Arginine Supplementation and Inflammation; 4.5. Arginine Supplementation and Cancer; 4.6. Arginine Supplementation and the Endocrine System; 4.6.1. Diabetes Mellitus; 4.6.2. Arginine and Growth Hormone; 4.7. Arginine in Pregnancy; 4.8. Arginine Utilization in Dentistry; 5. ARGININE SUPPLEMENTATION IN HEALTHY PERSONS; 5.1. Arginine Supplementation in Professional Physical Training; 5.2. Arginine Supplementation in Non-Professional Physical Training; 5.3. Arginine Supplementation in Healthy Persons as "Prevention"

5.4. A Short Summary on the Possible Risks of Arginine SupplementationCONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 2: L-ARGININE AND NITRIC OXIDE HOMEOSTASIS; ABSTRACT; 1. INTRODUCTION; 2. L-ARGININE - SUBSTRATE FOR NITRICOXIDE BIOSYNTHESIS; 2.1. L-arginine and Nitric Oxide Synthase; 2.2. L-arginine and Arginase; 2.3. NO-Synthase vs Arginase; 2.4. L-arginine Utilization by Other Enzymes; 3. L-ARGININE AND NITRIC OXIDE INPHYSIOLOGICAL CONDITION; 4. L-ARGININE AND NITRIC OXIDE IN PATHOLOGICAL CONDITION; 5. BIOAVAILABILITY OF L-ARGININE; 6. THERAPEUTIC USE OF L-ARGININE; CONCLUSION

ACKNOWLEDGMENTSREFERENCES; Chapter 3: L-ARGININE AND CARDIOMETABOLIC HEALTH: BRIEF OVERVIEW; ABSTRACT; INTRODUCTION; ARGININE AND CARDIOMETABOLIC HEALTH: MOLECULAR PATHWAYS; SAFETY AND POSSIBLE (DRUG-NUTRIENT) INTERACTIONS OF SUPPLEMENTAL ARGININE; CONCLUSION; REFERENCES; PROFESSIONAL APPOINTMENTS; EDUCATION; PUBLICATIONS (LAST 3 YEARS); Scientific papers; Book chapters; Chapter 4: NOVEL SYNTHETIC BIODEGRADABLE ARGININE-RICH IMPLANTABLE BIOMATERIALS AND DEVICES FOR HUMAN BODY REPAIR AND RECONSTRUCTION; ABSTRACT; 1. INTRODUCTION

2. BASIC CHEMICAL STRUCTURE OF AMINO ACID-BASED POLY(ESTER AMIDE)S AND POLY(ESTER UREA URETHANE)

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

1-63485-340-7