Fundamental neuroscience / edited by Larry R. Squire ... [et al.] ; illustrations by Robert S. Woolley.

Format:

Book

Contributor:

Squire, Larry R.

Language:

English

Subjects (All):

Neurosciences.

Physical Description:

1 online resource (1447 p.)

Edition:

2nd ed.

Place of Publication:

Amsterdam ; Boston : Academic Press, c2003.

Language Note:

English

Summary:

With over 300 training programs in neuroscience currently in existence, demand is great for a comprehensive textbook that both introduces graduate students to the full range of neuroscience, from molecular biology to clinical science, but also assists instructors in offering an in-depth course in neuroscience to advanced undergraduates.The second edition of Fundamental Neuroscience accomplishes all this and more. The thoroughly revised text features over 25% new material including completely new chapters, illustrations, and a CD-ROM containing all the figures from the text. More

Contents:

Cover; Full Contents; Preface to the First Edition; Preface to the Second Edition; Acknowledgments; Section I: Neuroscience; Chapter 1. Fundamentals of Neuroscience FLOYD E. BLOOM; A Brief History of Neuroscience; The Terminology of Nervous Systems Is Hierarchical, Distributed, Descriptive, and Historically Based; Neurons and Glia Are Cellular Building Blocks of the Nervous System; The Operative Processes of Nervous Systems Are Also Hierarchical; Cellular Organization of the Brain; Organization of This Text; This Book Is Intended for a Broad Range of Scholars of the Neurosciences

Clinical Issues in the NeurosciencesThe Spirit of Exploration Continues; The Genomic Inventory Is a Giant Step Forward; Neuroscience Today: A Communal Endeavor; The Creation of Knowledge; Responsible Conduct; Summary; References; Chapter 2. The Architecture of Nervous Systems LARRY W. SWANSON; General Principles from an Evolutionary Perspective; Development of the Vertebrate Nervous System; Identity and Organization of Functional Systems; Some Basic Structural Features of the Nervous System 32; Summary; References; Section II: Cellular and Molecular Neuroscience

Chapter 3. Cellular Components of Nervous TissueThe Neuron; Neuroglia; Cerebral Vasculature; Summary; References; Chapter 4. Subcellular Organization of the Nervous System: Organelles and Their Functions; Axons and Dendrites: Unique Structural Components of Neurons; Protein Synthesis in Nervous Tissue; Cytoskeletons of Neurons and Glial Cells; Molecular Motors in the Nervous System; Building and Maintaining Nervous System Cells; References; Chapter 5. Electrotonic Properties of Axons and Dendrites; Toward a Theory of Neuronal Information Processing

Basic Tools: Cable Theory and Compartmental ModelsSpread of Steady-State Signals; Spread of Transient Signals; Electrotonic Properties Underlying Propagation in Axons; Electrotonic Spread in Dendrites; Dynamic Properties of Passive Electrotonic Structure; Relating Passive to Active Potentials; References; Chapter 6. Membrane Potential and Action Potential; Membrane Potential; Action Potential; References; Chapter 7. Neurotransmitters; Several Modes of Neuronal Communication Exist; Chemical Transmission; Classical Neurotransmitters; Nonclassical Neurotransmitters; Peptide Transmitters

Unconventional TransmittersSynaptic Transmission in Perspective; References; Chapter 8. Release of Neurotransmitters; Transmitter Release Is Quantal; Excitation-Secretion Coupling; Molecular Mechanisms of the Nerve Terminal; Quantal Analysis: Probing Synaptic Physiology; Short-Term Synaptic Plasticity; References; Chapter 9. Neurotransmitter Receptors; Ionotropic Receptors; G-Protein Coupled Receptors; References; Chapter 10. Intracellular Signaling; Signaling through G-Protein-Linked Receptors; Modulation of Neuronal Function by Protein Kinases and Phosphatases

Intracellular Signaling Affects Nuclear Gene Expression

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-281-02111-3

9786611021115

0-08-052180-0

OCLC:

476073265