Molecular and Cellular Physiology of Neurons / Gordon L. Fain.

Format:

Book

Author/Creator:

Fain, Gordon L., Author.

O'Dell, Thomas, 1960- author.

Language:

English

Subjects (All):

Neurophysiology.

Neurons.

Molecular neurobiology.

Physical Description:

1 online resource (752 p.)

Edition:

2nd ed.

Place of Publication:

Cambridge, MA : Harvard University Press, [2014]

Language Note:

English

Summary:

Molecular and Cellular Physiology of Neurons, Second Edition is a comprehensive, up-to-date introduction to essential concepts of cellular neuroscience. Emphasizing experimental approaches and recent discoveries, it provides an in-depth look at the structure and function of nerve cells, from protein receptors and synapses to the biochemical processes that drive the mammalian nervous system. Starting with the basics of electrical current flow across cell membranes, Gordon Fain covers voltage gating and receptor activation in the context of channel diversity, excitatory and inhibitory synaptic transmission, neuromodulation, and sensory transduction. Emphasizing long-term processes of synaptic potentiation and depression involved in memory, consciousness, and attention, he demonstrates how cells produce neural signals and regulate signal flow to enhance or impede cell-to-cell communication. Fain also addresses the relation of molecular and cellular mechanisms to evolving theories of neurological disease and addiction. Enhanced by more than two hundred illustrations, Molecular and Cellular Physiology of Neurons, Second Edition is intended for anyone who seeks to understand the fundamentals of nerve cell function, including undergraduate and graduate students in neuroscience, students of bioengineering and cognitive science, and practicing neuroscientists who want to deepen their knowledge of recent discoveries in molecular and cellular neurophysiology.

Contents:

Frontmatter

Contents

Preface

1. Introduction

2. Electrical Properties of Neurons

3. Ion Permeability and Membrane Potentials

4. Ion Pumps and Homeostasis

5. Action Potentials: The Hodgkin-Huxley Experiments

6 The Structure and Function of Voltage- Gated Na+ and K+ Channels

7. The Diversity of Ion Channels

8. Presynaptic Mechanisms of Synaptic Transmission (revised by Thomas J. O’Dell)

9. Excitatory Transmission

10. Inhibitory Transmission (revised by Thomas J. O’Dell)

11. Metabotropic Transmission: Receptors and G Proteins

12. Metabotropic Transmission: Effector Molecules

13. Metabotropic Transmission: Calcium

14. Long- Term Potentiation (originally written and newly revised by Thomas J. O’Dell)

15. Mechanoreceptors

16. Photoreceptors and Olfactory Receptor Neurons

Appendix: Symbols Used

References

Index

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on online resource; title from PDF title page (publisher's Web site, viewed 23. Jun 2020)

Description based on publisher supplied metadata and other sources.

ISBN:

9780674967489

0674967488

9780674735644

0674735641

OCLC:

979743591