From biotechnology to genomes : the meaning of the double helix / Philippe Goujon.

Format:

Book

Author/Creator:

Goujon, Ph. (Philippe)

Language:

English

Subjects (All):

Gene mapping--Forecasting.

Gene mapping.

Human gene mapping--Forecasting.

Human gene mapping.

Biotechnology--Technological innovations--Forecasting.

Biotechnology.

Physical Description:

1 online resource (807 p.)

Place of Publication:

Singapore ; [River Edge], NJ : World Scientific Pub. Co., c2001.

Language Note:

English

Summary:

Aimed at scientists and non-specialised readers alike, this book retraces the source of national and international biotechnology programmes by examining the origins of biotechnology and its political and economic interpretation by large nations. With a foreword by André Goffeau, who initiated the European Yeast Genome Project, the book describes the achievements of the first genetic and physical maps, as well as the political and scientific genesis of the American Human Genome Project. Following these advances, the author discusses the European biotechnology strategy, the birth and implementation of European biotechnology programmes and the yeast genome project. After a detailed description of scientific policy and administrative, technical and scientific achievements, the principal stages of the yeast project and its major benefits are discussed. This enables the reader to obtain a panoramic view of this developing discipline at the dawn of the twenty-first century, as well as a better knowledge of the means deployed at international level. The conclusion gives a very detailed account of the genesis and early stages of this new scientific and technological field called genomics which appears to be a key component of modern industry. By using an epistemological analysis, the conclusion poses the problem of a new representation of life and critically appraises the limitations and deficiencies.

Contents:

Foreword; Introduction: The Essence of Life and the Labyrinth of the Genome; Contents; 1 The Invention of Biotechnology; 1.1 The Origins of Biotechnology; 1.2 The Emergence of a New Concept of Life; 1.3 From Zymotechnology to Biotechnology; 1.4 The Engineering of Nature - Towards the Best of all Possible Worlds; 1.5 Technique, Biology and the Development of Biotechnics; 1.6 The Recognition of Biotechnology by the Institutions; 2 Political Interpretations of Biotechnology and the Birth of the First Research Programs; 2.1 The Example of the United States

2.2 Biotechnology in Japan : Economic Success and Ecological FaiIure2.3 Germany and the Political Aspect of Biotechnology; 2.4 The British Development of Biotechnology: Delayed PoIiticaI Reaction; 2.5 The French Reaction; 2.6 The European Community and Biotechnology- The Emergence of the First European Biotechnology Programs; 3 The Foundations of the Heralded RevoIution; 3.1 From the Frontiers of Genetics to the Birth of Molecular Biology; 3.2 The Secret of Life: DNA; 3.3 The First Sequencing of a Protein: Insulin; 3.4 Techniques of DNA Sequencing

3.5 Gene Money, or the Miracles Expected of Biotechnology3.6 The JapaneseThreat and the Human Frontier Science Program; 4 Attack on the Cenomes: The First Genetic and Physical Maps; 4.1 The Problem of Gene Localization; 4.2 Polymorphic Markers, Gene Mapping and the Great Gene Hunt; 4.3 Towards a Complete Linkage Map; 4.4 Physical Genome Mapping: The Reconstruction of a Complicated Puzzle; 4.5 The First Physical Maps of large Cenomes; 4.6 Towards a Physical Map of the Human Genome; 5 The Human Genome Project and the International Sequencing Programs

5.1 The Ultimate Challenge: The Human Genome Project5.2 The Department of Energy Initiative; 5.3 The NIH Genome Project; 5.4 HUGO, or the Difficulties of International Coordination; 5.5 The Importance of Model Organisms; 5.6 The lnternational Dimensions of Genome Research: The First Stirrings in other Countries; 6 European Biotechnology Strategy and Sequencing the Yeast Genome; 6.1 Towards a New European Research Policy for Biotechnology; 6.2 The 1980s: An Implementation of the 1983 Strategy?; 6.3 BAP's First Year; 6.4 The Revision of the BAP Program

6.5 The Origins and Nature of the Yeast Genome Sequencing Project6.6 Critical Discussions and the Adoption of the Yeast Genome Sequencing Project; 7 The Decryption of Life; 7.1 The Structure and Organization of the European Yeast Genome Sequencing Network; 7.2 A World First -The Sequence for a Whole Eucaryote Chromosome: Chromosome III of the Yeast Saccharomyces cerevisiae; 7.3 The Complete Sequence of the Genome and the Intensification of European Efforts; 7.4 After The Sequence - The Challenge of Functional Analysis; 7.5 Sequences, Sequences and More Sequences; 7.6 From Science to Economics

8 Conclusion: The Dreams of Reason or the New Biology's Dangerous Liaisons

Notes:

Description based upon print version of record.

Includes bibliographical references and indexes.

ISBN:

9786611869687

9781281869685

1281869686

9789812384874

9812384871

OCLC:

52274513