Protein targeting and translocation / edited by D.A. Phoenix.

Format:

Book

Contributor:

Phoenix, David, 1966- editor.

Series:

Portland Press research monograph ; 12.

Portland Press research monograph, 0964-5845 ; 12

Princeton legacy library

Language:

English

Subjects (All):

Proteins--Physiological transport.

Proteins.

Proteins--Secretion.

Physical Description:

1 online resource (305 p.)

Edition:

Core Textbook

Place of Publication:

Princeton, New Jersey : Princeton University Press, [1998]

Language Note:

English

Summary:

Protein targeting is a fast-moving field that has encompassed areas from biophysics to molecular biology to try to gain insight into how proteins are directed to their final functional location and how such macromolecules are able to cross semi-permeable membrane barriers during their journey. This text reviews our current state of knowledge regarding the interaction of proteins at the membrane interface and the assembly of proteins into biological membranes, before proceeding to look at targeting pathways in both prokaryotic and eukaryotic systems. The reviews have been written by some of the leading researchers in the field, with contributions from around the world and with more than 1,800 references. The text is aimed at graduate students and at researchers with an interest in protein targeting, but may also be of use to final-year undergraduates.Originally published in 1999.The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Contents:

Frontmatter

Contents

Preface

Abbreviations

Membrane interactions

Biophysics of the membrane interface and its involvement in protein targeting and translocation / Watts, A. / Pinheirof, T.J.T.

Amphiphilic α-helices and lipid interactions

Signal sequences: initiators of protein translocation / Nouwen, N. / Tommassen, J. / Kruijff, B. de

Determinants of membrane protein topology and membrane anchoring / Hashemzadeh-Bonehit, Lida / Jacob, Jansen P. / Mitsopoulos, Costas / Broome-Smith, Jenny K.

Insertion of single- and multispanning proteins into the bacterial cytoplasmic membrane / Kiefer, D. / Kuhn, A.

Prokaryotic protein translocation / Driessen, Arnold J. M.

Protein traffic from the cytosol to the outer membrane of Escherichia coli / Tokuda, H. / Matsuyama, S.

sec-dependent prokaryotic protein secretion / Thomas, J.D. / Wharamf, S.D. / Salmond, G.P.C.

Targeting and assembly of fimbriae / Smyth, C.J. / Smith, S.G.J. / Marron, M.B.

Targeting to and translocation across the endoplasmic reticulum membrane / Brodsky, Jeffrey L.

Protein localization to the endoplasmic reticulum and Golgi complex / Qanbar, R. / Machamer, C.E.

Import and export of proteins at the nucleus / Imamotol, Naoko / Miyamoto, Yoichi / Yoneda, Yoshihiro

Mitochondrial targeting and import / Hovius, Ruud

Translocation of proteins into and across the thylakoid membrane / Robinson, Colin / Mant, Alexandra / Brink, Susanne

Principles of peroxisomal protein sorting and assembly / Kiel, J.A.K.W. / Klei, I.J. van der / Veenhuis, M.

Targeting of glyoxysomal proteins / Baker, A. / Tugal, B.

Subject index

Notes:

Description based upon print version of record.

Description based on print version record.

Includes bibliographical references and index.

ISBN:

0-691-63598-6

0-691-60739-7

1-4008-6501-8

OCLC:

884012754