Pioneers of medicine without a nobel prize / Gilbert Thompson, editor ; contributors Bhavna Batohi [and twenty two others].

Format:

Book

Contributor:

Thompson, Gilbert, editor.

Batohi, Bhavna, contributor.

Language:

English

Subjects (All):

Medicine--History.

Medicine.

Physical Description:

1 online resource (295 p.)

Place of Publication:

London, England : Imperial College Press, 2014.

Language Note:

English

Summary:

This book brings together in one volume fifteen discoveries that have had a major impact upon medical science and the practice of medicine but where the scientists involved have not been awarded a Nobel Prize. Its aim is to publicize the achievements of these lesser-known heroes of our time and thereby inform and entertain the reader, whether medical student, professor or scientifically-minded layman. Contents: Archibald E Garrod: The Founding Father of Biochemical Genetics (David J Galton); Nikolai Anitschkow: The Birth of the Lipid Hypothesis of Atherosclerosis and Coronary Heart Disease (Da

Contents:

CONTENTS; Foreword; Preface; Acknowledgements; Contributors; Chapter 1 Archibald E. Garrod: The Founding Father of Biochemical Genetics; 1.1 Introduction; 1.1.1 Discovery of the inborn errors of metabolism (1901); 1.1.2 First application of Mendelian genetics to clinical medicine (1902); 1.1.3 First recognition of 'gene'-enzyme relationships (1902); 1.1.4 First ideas on chemical individuality (1902); 1.1.5 Inherited liability to metabolic disease (1908); 1.2 Biography; 1.3 Research Methods; 1.3.1 Organic chemistry; 1.3.2 Pedigree analysis; 1.3.3 Feeding experiments

1.4 Scope of Garrod's Impact1.4.1 Inborn errors of metabolism; 1.4.2 Mutation research; 1.4.3 Garrod's liability factors; 1.4.4 Garrod's ideas on chemical individuality; 1.5 Conclusion; Acknowledgements; References; Chapter 2 Nikolai Anitschkow: The Birth of the Lipid Hypothesis of Atherosclerosis and Coronary Heart Disease; 2.1 Introduction; 2.2 Were the Findings of Sufficient Importance to Merit a Nobel Prize?; 2.3 State-of-the-Science in 1913; 2.4 Anitchkow's Contributions; 2.5 Notes on the Man and the Venue of his Discoveries; 2.6 Was Anitschkow's Work Heuristic?

2.7 What led Anitschkow to Feed Rabbits Cholesterol?2.8 Conclusion; References; Chapter 3 Willem-Karel Dicke: The Role of Gluten in Coeliac Disease; 3.1 Introduction; 3.2 Biography: The Man who Missed the Nobel Prize in 1962; 3.3 Dicke's Research into the Role of Gluten in Coeliac Disease; 3.4 Current Knowledge of the Spectrum of Gluten Related Disorders; 3.4.1 Coeliac disease; 3.4.1.1 Quality of life of asymptomatic CD on a GFD; 3.4.1.2 GFD in daily practice; 3.4.1.3 Evaluation of dietary compliance in coeliac disease; 3.4.1.4 Supportive treatment for those in need of a GFD

3.4.2 Dermatitis herpetiformis3.4.3 Gluten ataxia; 3.4.4 Wheat intolerance; 3.4.5 Non-coeliac gluten sensitivity; 3.4.6 Overall conclusions; 3.5 Epilogue: Willem-Karel Dicke; References; Chapter 4 Richard Doll: The Link Between Smoking and Lung Cancer; 4.1 Introduction; 4.2 Biographical Sketch; 4.3 Nature of the Medical Problem; 4.4 Description of the Research; 4.5 Impact of the Discoveries on Medical Science; Acknowledgements; References; Chapter 5 Albert Sabin: The Development of an Oral Poliovirus Vaccine; 5.1 Introduction; 5.2 The Early Years of Albert Sabin

5.3 The Historical Development of Poliovirus Knowledge5.4 The Development of a Poliovirus Vaccine; 5.5 Albert Sabin: Publications and Recognition; 5.6 Why the Sabin Vaccine was a Pioneering Development; 5.7 The Sabin Vaccine Today; 5.8 Albert Sabin, Polio and the Nobel Prize; 5.9 Epilogue; Acknowledgements; References; Chapter 6 René Favaloro: Pioneer of Coronary Artery Surgery; 6.1 The Beginning; 6.2 The Origins of Coronary Artery Surgery; 6.3 At the Cleveland Clinic; 6.4 Favaloro and Sones; 6.5 Return to Argentina; 6.6 Conclusion; References

Chapter 7 Christiaan Barnard and Norman Shumway: The Heart Transplant Pioneers

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

1-78326-384-9

1-78326-385-7