Clinical psychopharmacology : a practical approach / Humberto Marin, Javier I. Escobar, Rutgers University's Robert Wood Johnson Medical School, USA.

Format:

Book

Author/Creator:

Humberto, Marin.

Escóbar, Javier, author.

Series:

Gale eBooks

Language:

English

Subjects (All):

Psychotropic drugs.

Mental illness--Chemotherapy.

Mental illness.

Physical Description:

1 online resource (xx, 286 pages)

Place of Publication:

New Jersey : World Scientific, [2013]

Language Note:

English

Summary:

This innovative handbook is for young practitioners in psychiatry and primary care, as well as psychiatric and non-psychiatric residents. The focus of this book is on practical clinical psychopharmacology that would fit best an outpatient clinical setting (non-emergency). Besides reviewing psychotropic drugs, it takes a practical approach, making detailed practical recommendations on the use of currently available psychiatric drugs. It also addresses important related topics, such as antidepressant treatment and suicide, and the use of psychotropic medications in special circumstances such as

Contents:

Preface; Contents; Chapter 1 Absorption, Transformation, and Elimination of Psychotropic Medications; 1.1 Absorption; 1.1.1 Oral administration; 1.1.2 Sublingual administration ("under the tongue"); 1.1.3 Transdermal administration; 1.1.4 Respiratory administration, intranasal or inhalation; 1.1.5 Short-acting injectable forms; 1.1.6 Long-acting injectable preparations; 1.2 Distribution: Differences Between Serum and Cerebrospinal Fluid/Brain Concentrations; 1.3 Metabolism and Elimination; 1.3.1 Phase I metabolism; 1.3.1.1 Inhibition and induction of CYP450 enzymes

1.3.2 Phase II metabolism (conjugation)1.3.2.1 Inhibition and induction of conjugation enzymes; 1.4 Additional Concepts in Pharmacokinetics; 1.4.1 Steady state; 1.4.2 Dose-response relationship; 1.4.3 Therapeutic margin; Chapter 2 Neurotransmitters, Receptors, and Transporters; 2.1 Main Types of Receptors in the Brain; 2.1.1 Division of receptors according to the processes they trigger; 2.1.1.1 Ionotropic receptors; 2.1.1.2 Metabotropic receptors; 2.1.1.3 Receptor tyrosine kinases; 2.1.1.4 Nuclear receptors; 2.1.1.5 Receptors associated with neurotransmitter pumps

2.1.2 Division of receptors according to their localization in pre- or post-synaptic neurons2.1.2.1 Autoreceptors; 2.1.2.2 Heteroreceptors; 2.2 Neurotransmitters; 2.2.1 Serotonin; 2.2.1.1 Types of serotonin receptors; 2.2.2 Dopamine; 2.2.2.1 Types of dopamine receptors; 2.2.3 Norepinephrine; 2.2.3.1 Types of norepinephrine receptors; 2.2.4 Acetylcholine; 2.2.4.1 Types of cholinergic receptors; 2.2.5 Glutamate; 2.2.5.1 Glutamate activity and neuroplasticity; 2.2.5.2 Types of glutamate receptors; 2.2.6 GABA; 2.2.6.1 Types of GABA receptors; 2.2.7 Histamine; 2.2.7.1 Types of histamine receptors

2.3 Neurotransmitter Reuptake TransportersReferences; Chapter 3 Antipsychotics: A General View of Therapeutic and Adverse Effects; 3.1 Classic Antipsychotics; 3.2 New Antipsychotics; 3.3 Are the New Antipsychotics Clinically Different from the Old Ones?; 3.4 Current Concepts Regarding Antipsychotic Action and the D2 Receptor; 3.5 Comparison Between Typical and Atypical Antipsychotics; 3.5.1 Are there differences in the general efficacy and effectiveness of typical and atypical antipsychotics?; 3.5.2 Are there differences in the cognitive effects of typical and atypical antipsychotics?

3.5.3 Are there differences in the acute toxicity of typical and atypical antipsychotics?3.6 Metabolic Side Effects of Antipsychotic Drugs; 3.6.1 Weight gain risk with antipsychotics; 3.6.2 Antipsychotic-induced diabetes mellitus and metabolic syndrome; 3.7 Extrapyramidal Symptoms of Antipsychotics; 3.7.1 Are there any differences in the risk for EPS among typical and atypical antipsychotics?; 3.7.2 Acute dystonia; 3.7.3 Parkinsonism (slowness, tremor, and rigidity); 3.7.4 Akathisia; 3.7.4.1 Clozapine; 3.7.4.2 Risperidone; 3.7.4.3 Olanzapine; 3.7.4.4 Quetiapine; 3.7.4.5 Ziprasidone

3.7.4.6 Aripiprazole

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

9789814343664

9814343668

OCLC:

860388912