Septic shock : risk factors, management and prognosis / Benedict Graver, editor.

Format:

Book

Contributor:

Graver, Benedict, editor.

Series:

Emergency and Intensive Care Medicine

Language:

English

Subjects (All):

Septic shock.

Septic shock--Risk factors.

Septic shock--Treatment.

Septic shock--Prognosis.

Physical Description:

1 online resource (165 p.)

Place of Publication:

New York : Nova Biomedical, 2015.

Language Note:

English

Summary:

In a 2013 Healthcare Cost and Utilization Project Statistical Brief by the US Agency for Healthcare Research and Quality, septicemia was ranked as the number one most expensive national inpatient hospital cost. This ranking comes in spite of substantial advances in the clinical management of sepsis over the past fifteen years. While adherence with internationally established sepsis management protocols have demonstrated reduction in mortality and hospital/ICU length of stay, compliance with these protocols remains poor. This book discusses risk factors, management and prognosis of septic shock

Contents:

SEPTIC SHOCK: RISK FACTORS, MANAGEMENT AND PROGNOSIS; SEPTIC SHOCK: RISK FACTORS, MANAGEMENT AND PROGNOSIS; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter I: Septic Shock Electronic Surveillance; Abstract; Detection of Sepsis: Historical Perspective and Current Status (Non-Computerized); Computerized Attempts of Sepsis Detection; Limitations and Challenges of Early Computerized Systems; Elements of an Advanced Computerized System; What EMR Data Is Needed?; Workflow Changes, Educational Challenges, and Implementation; Perspectives

Future Algorithm Improvements for Electronic SurveillanceBullet Points; References; Chapter II: Severe Sepsis and Septic Shock: Different Concepts of Analgesia and Sedation May Have Important Influences on Prognosis and Therapy Management; Introduction; Background; Methods; Results; Discussion; Conclusion; Conflicts of Interest; References; Chapter III: Angiogenesis-Related Factors and Their Pivotal Role In Septic Shock: A Novel Therapeutic Target and Prognostic Tool; Abstract; Abbreviations; Introduction; 1. Angiogenesis-Related Factors; 2. Septic Shock Pathophysiology and ARF

3. ARF As Biomarkers of Septic Shock4. ARF As Potential Therapeutic Tools; Conclusion; References; Chapter IV: Membrane-Bound and Soluble Triggered Receptor Expressed on Myeloid Cells 1 (TREM-1)Discriminates Sepsis from Other Causes of Systemic Inflammation; Abstract; Introduction; Patients and Methods; Laboratory Methods; Results; Discussion; References; Chapter V: Bridging Danger Signals from within and without: High Mobility Group Box 1; Abstract; Abbreviations; Introduction; DAMPs: Signature of Danger; HMGB1 Structure and Post-Translational Modifications

HMGB1 Heterocomplex Formation with Other Danger SignalsMechanism of Action; Targeting HMGB1 in Sepsis; Detection of HMGB1 and Correlation to Severe Sepsis Severity in Humans; Conclusion; Acknowledgments; References; Index

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

1-63463-948-0