2 options
Methotrexate : pharmacology, clinical uses and adverse effects / Valentina S. Castillo and Laura A. Moyano, editors.
- Format:
- Book
- Series:
- Pharmacology-research, safety testing, and regulation series.
- Pharmacology-research, safety testing and regulation
- Language:
- English
- Subjects (All):
- Methotrexate.
- Tumors--Treatment.
- Tumors.
- Physical Description:
- 1 online resource (280 p.)
- Place of Publication:
- Hauppauge, N.Y. : Nova Science Publishers, c2012.
- Language Note:
- English
- Summary:
- Methotrexate (MTX) is an important component of therapy in several immune diseases (rheumatoid arthritis, psoriasis, and cancers such as acute lymphoblastic leukaemia, osteosarcoma, ovarian cancer and others). Despite its clinical success, treatment with MTX often causes toxicity, dose reduction or treatment cessation. In this book, the authors present topical research in the study of the pharmacology, clinical uses and adverse effects of methotrexate. Topics discussed include lipid alterations instigated by methotrexate; acute toxicity of high doses of methotrexate in the treatment of lymphoblastic leukaemia in children; pharmacogenetics update on MTHFR and methotrexate toxicity; animal models of cognitive impairment induced by methotrexate and damage, as well as the recovery of the bone and bone marrow following methotrexate chemotherapy.
- Contents:
- Lipid alterations instigated by methotrexate and leucovorin in female reproductive tract of albino rats / Karri Sritulasi, G. Vanithakumari, and Coimbatore Gopalakrishnan
- Acute toxicity of high doses of methotrexate in the treatment of linfoblastic leukemia in children : a case report / Leonor Perianez Parraga ... [et al.]
- Pharmacogenetics update on MTHFR and methotrexate toxicity / Elixabet Lopez-Lopez, Nerea Bilbao
- Methotrexate : pharmacology, clinical uses, and adverse effects / Usha Verma, Nipun Verma
- Low dose methotrexate : pharmacology, clinical uses, and adverse effects / A.N. Patel, D.P. Hawley, and S. Rangaraj
- Methotrexate : update on pharmacology, clinical applications, and warnings / Marcelo Derbli Schafranski ... [et al.]
- Factors predicting clinical adverse events during high-dose methotrexate therapy / Yuko Kanbayashi, Masafumi Taniwaki
- Animal models of cognitive impairment induced by methotrexate / Laura Lyons, Geoff Bennett, and Peter Wigmore
- Damage and recovery of the bone and bone marrow following methotrexate chemotherapy / Kristen R. Georgiou, Cory J. Xian
- The effects of [beta]-glucan isolated from pleurotus otreatus on methotrexate treatment in rats with adjuvant arthritis / Jozef Rovensky ... [et al.]
- TGF-B and MMPs : a complex regulatory loop involved in tumor progression / Miguel Quintanilla ... [et al.].
- Notes:
- Description based upon print version of record.
- Includes bibliographical references and index.
- ISBN:
- 1-62100-655-7
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.