Chronic inflammation : causes, treatment options and role in disease / Wei-Chiao Chang, Wen-Chang Chang, editors.

Format:

Book

Contributor:

Chang, Wei-Chiao.

Chang, Wenchang.

Series:

Immunology and Immune System Disorders

Immunology and Immune System Disorder

Language:

English

Subjects (All):

Inflammation.

Inflammation--Immunological aspects.

Physical Description:

1 online resource (258 p.)

Place of Publication:

New York : Nova Biomedical, c2013.

Language Note:

English

Summary:

The primary focus of this book is to provide readers with a comprehensive overview of the recent advances in inflammation, especially in molecular biological and clinical aspects. Chapters contained in this book are written by invited authors from all over the world, who are well-known experts in their respective fields. In the book, chapters discussed include the molecular basis of inflammatory mechanisms, the functional roles of inflammation in diseases and new treatments of anti-inflammation. This book will be useful to all who wish to understand the scientific basis of inflammatory disease

Contents:

""CHRONIC INFLAMMATION ""; ""CHRONIC INFLAMMATION ""; ""Library of Congress Cataloging-in-Publication Data ""; ""Contents ""; ""Preface ""; ""Chapter I The Role of Store-Operated Calcium Channel in Chronic Inflammation ""; ""Abstract ""; ""1. Calcium Signaling in Physiological Functions ""; ""(1). The Versatility of CaSignaling ""; ""(2). The Sources of CaSignals ""; ""(3). The OFF Mechanisms ""; ""(4). Spatial and Temporal Regulation of Ca2+ Signaling ""; ""2. Molecular Identification of Store-Operated Calcium Channel ""; ""(1). The Discovery of Store-Operated Calcium Current ""

""(2). Experimental Regulation of Store-Operated Calcium Channels """"(3). The Identification of STIM1 and Orai1/CRACM1 ""; ""3. Role of Store-Operated Calcium Channel Ininflammatory Reactions ""; ""(1). Store-Operated Calcium Channel and Allergic or Vascular Inflammation""; ""(2). Store-Operated Calcium Channel and Inflammatory COX-2 Gene Expression ""; ""4. Role of Store-Operated Calcium Channel in Cancer ""; ""(1). Dysregulated Store-Operated Ca2+ Entry in Cancer ""; ""(2). Store-Operated Ca2+ Entry in Cancer Cell Migration, Invasion and Metastasis ""

""(3). Store-Operated CaEntry in Cancer Growth """"(4). Molecular Mechanisms by Which SOCE Promotes Cancer Progression ""; ""5. Genetic Polymorphisms of Store-OperatedCalcium Channel and Inflammatory Diseases""; ""Conclusion ""; ""Acknowledgments ""; ""References ""; ""Chapter II The Role of NF- B in Chronic Inflammation""; ""Abstract ""; ""Abbreviations ""; ""1. Introduction ""; ""(1). The Inflammatory Process ""; ""(2). Phases of the Inflammatory Process ""; ""Acute Inflammation ""; ""Resolution of Inflammation ""; ""(3). Chronic Inflammation ""; ""Chronic Inflammatory Cells ""

""2. NF- B """"(1). NF- B Links Chronic Inflammation and Cancer ""; ""(2). Current Strategies to Prevent NF- B Activation ""; ""Conclusion ""; ""References ""; ""Chapter III The Role of Autophagy in Inflammatory Bowel Diseases ""; ""Abstract ""; ""1. Inflammatory Bowel Disease ""; ""(1). Diagnosis and Etiology ""; ""(2). Immunity and Inflammation ""; ""(3). Microbiota ""; ""(4). Genetics""; ""2. Autophagy and Molecular Mechanisms ""; ""(1). Autophagy in Human Diseases ""; ""(2). Autophagy in Inflammation and Immunity""; ""(2.1). Autophagy and IBD ""; ""(3). Conclusion and Perspectives ""

""References """"Chapter IV Chronic Inflammation of Ankylosing Spondylitis ""; ""Abstract ""; ""1. Introduction ""; ""2. Epidemiology ""; ""3. Causes and Genetics ""; ""4. Immunopathogenesis ""; ""Molecular Mimicry Theory� and “Arthritogenic Peptide Theory ""; ""HLA-B27 Free-Heavy-Chain Hypothesis ""; ""ER Stress Theory ""; ""5. Clinical Manifestations ""; ""6. Diagnosis and Classification ""; ""7. Management ""; ""Conclusion ""; ""References ""; ""Chapter V Chronic Inflammation of Kawasaki Disease""; ""Abstract ""; ""1. Introduction""; ""2. Inflammation in Kawasaki Disease ""

""3. Th1 response in Kawasaki Disease ""

Notes:

Description based upon print version of record.

Description based on online resource; title from title page (ebrary, viewed September 12, 2013).

Includes bibliographical references at the end of each chapters and index.

ISBN:

1-62808-095-7

OCLC:

868950980