Cerebral small vessel disease / edited by Leonardo Pantoni, MD, PhD, Staff Neurologist, Stroke Unit and Neurology Azienda Ospedaliero Universitaria Careggi, Florence, Italy, Philip B. Gorelick, MD, MPH, Professor of Translational Science and Molecular Medicine, Michigan State University College of Human Medicine, Medical Director, Hauenstein Neuroscience Center, Mercy Health at Saint Mary's, Grand Rapids, MI, USA.

Format:

Book

Contributor:

Pantoni, L., editor.

Gorelick, Philip B., editor.

Series:

Cambridge medicine Cerebral small vessel disease

Language:

English

Subjects (All):

Cerebrovascular disease.

Physical Description:

1 online resource (xiv, 360 pages) : digital, PDF file(s).

Place of Publication:

Cambridge : Cambridge University Press, 2014.

Language Note:

English

Summary:

Small vessel disease is an important frontier in neurology; about 25% of strokes are classified as small vessel, and SVD is the most common cause of vascular cognitive impairment. The risk of developing SVD increases with age, making this a growing concern for countries with aging populations. Despite this, there has been a paucity of information about its causes, diagnosis, prevention and treatment. This volume brings together contributions from leading international experts in the field and discusses pathogenesis, pathophysiology, clinical and radiologic manifestations, prevention and treatment modalities, and future directions for research and practice. Genetic forms of SVD are discussed, as well as the rapid development of neuroimaging techniques as tools for screening and treatment. This authoritative book is essential reading for neurologists, stroke physicians, geriatricians, and interventional neuroradiologists, as well as researchers in the fields of aging and dementia.

Contents:

""Cover""; ""Half title ""; ""Title ""; ""Copyright ""; ""Dedication ""; ""Contents ""; ""Contributors ""; ""Preface ""; ""Section 1 Classification, pathology, and basic aspects ""; ""Chapter 1 Definition and classification of small vessel diseases""; ""Introduction ""; ""Definition of cerebral SVDs and nosologic issues ""

""Etiologic classification of cerebral SVD """"New developments in the field of the definition of SVD ""; ""References ""; ""Chapter 2 Pathology of cerebral small vessel disease""; ""Introduction ""; ""Materials and methods ""; ""Hypertensive vasculopathy ""; ""Cerebral amyloid angiopathy (CAA) ""; ""Discussion ""

""Conclusion """"Acknowledgements""; ""References ""; ""Chapter 3 Pathologic aspects of the ischemic consequences of small vessel disease on brain parenchyma""; ""Introduction ""; ""Pathology ""; ""Focal lesions: subcortical lacunes ""; ""Focal lesions: cortical microinfarcts ""; ""Nonfocal lesions ""; ""Focal lesions caused by global brain ischemia ""

""Assessment of SVD and its contribution to motor and cognitive dysfunction in the elderly """"Conclusion ""; ""References ""; ""Chapter 4 Pathologic aspects of the hemorrhagic consequences of small vessel disease on the brain""; ""Introduction ""; ""Intracerebral hemorrhage ""; ""Neuropathology of intracerebral hemorrhage ""

""Hypertensive arteriopathy, CAA, and ICH """"Anticoagulation-related ICH ""; ""SAH and superficial siderosis ""; ""Cerebral microbleeds ""; ""Epidemiology of CMBs ""; ""Neuropathologic correlates of neuroimaging ""; ""Pathogenesis of CMBs ""; ""Relationship between ICH and CMBs ""; ""References ""

""Chapter 5 Experimental animal models of cerebral small vessel disease""

Notes:

Title from publisher's bibliographic system (viewed on 05 Oct 2015).

Includes bibliographical references at the end of each chapters and index.

ISBN:

1-139-95026-6

1-139-96193-4

1-139-94921-7

1-139-95982-4

1-139-96088-1

1-139-38269-1

1-139-95876-3

1-139-95664-7

1-139-95771-6

OCLC:

879421733