Introduction to organ transplantation / edited by Nadey S Hakim ; foreword by David Taube.

Format:

Book

Contributor:

Nadey, Hakim.

Language:

English

Subjects (All):

Transplantation of organs, tissues, etc.

Physical Description:

1 online resource (265 p.)

Edition:

2nd ed.

Place of Publication:

London : Imperial College Press, 2012.

Language Note:

English

Summary:

This second edition of the introduction to the field of organ transplantation provides an excellent overview of the tremendous progress made in recent decades, and gives a clear description of the current status of transplant surgery for students and trainees with an interest in this field. It opens with introductory chapters on the history of transplantation and the basic science of immunobiology, and then examines through an organ-based structure the practice of transplantation in each major system, from skin to intestine. There is a 13-year gap between the first and second edition, and this

Contents:

Contents; Contributors; Foreword; 1. History of Organ and Cell Transplantation Nadey S. Hakim and Vassilios Papalois; 1.1 HLA and Transplantation Immunology; 1.1.1 Initial use of cell culture methodologies to detect major histocompatibility complex (MHC) products; 1.1.2 Genomic organization of the HLA complex; 1.1.3 Organizations; 1.2 Organ Donation and Sharing; 1.2.1 The early kidney programmes; 1.2.2 The exchange programmes; 1.2.3 The donors; 1.2.4 Brain death; 1.2.5 The nonrenal organs; 1.3 The History of Kidney Transplantation; 1.3.1 1902-1912: Experimental efforts of Ullmann and Carrel

1.3.2 1906-1913: Initial kidney transplants from animals to humans1.3.3 1936: First unsuccessful kidney transplant between humans; 1.3.4 1943-1944: Medawar's explanation of graft destruction due to 'biological incompability', as described by Carrel; 1.3.5 1947-1953: Initial unsuccessful allotransplants after World War II; 1.3.6 1959: First successful kidney transplant between nonidentical twins; 1.3.7 1960: First successful kidney transplant between nontwin siblings; 1.3.8 1960-1961: First successful kidney transplant between nonsiblings

1.3.9 1961-1962: First kidney transplants using azathioprine1.3.10 1962: First successful cadaveric kidney transplant using immunosuppression; 1.4 The History of Liver Transplantation; 1.5 Multi-Visceral Transplants; 1.6 The History of Pancreas Transplantation; 1.6.1 Clinical chronology; 1.6.2 Evolution of recipient selection and programme development; 1.7 The Development of Islet Transplantation; 1.7.1 The first successful islet isolation and transplantation

1.7.2 Development of techniques for identification, tissue culture and cryopreservation of islet tissue, and assessment of islet viability and function1.7.3 Clinical islet transplantation; 1.8 The History of Intestinal Transplantation; 1.8.1 The world experience; 1.8.2 The Pittsburgh experience; 1.8.3 Future prospects; 1.9 The History of Heart Transplantation and Heart Valve Transplantation; 1.9.1 Clinical heart transplantation in humans; 1.9.2 Heart valve transplantation; 1.10 Lung Transplantation; 1.10.1 Living-related lobar lung transplantation; 1.11 Bone Marrow Transplantation

1.11.1 Early attempts at BMT1.11.2 The new era; 1.11.3 New developments; 1.12 Arm Transplantation; References; 2. Ethical Issues in Transplantation Miran Epstein; 2.1 The Political Economy of Transplantation; 2.1.1 The demand for organs; 2.1.2 The supply of organs; 2.2 Two Great Solutions; 2.3 The Ethical Discourse: Procurement of Organs; 2.3.1 Prosthetic implants; 2.3.2 Xenogeneic organs; 2.3.2.1 Clinical trials involving human research subjects; 2.3.2.2 The use or abuse of animals; 2.3.2.3 A financial bubble?; 2.3.3 Human organs; 2.3.3.1 Organs from the dead

An expanding definition of death

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

9786613784186

9781281603494

128160349X

9781848168558

1848168551

OCLC:

804661870