Differential diagnosis in neurology / Robert Jay Schwartzman.

Format:

Book

Author/Creator:

Schwartzman, Robert J., 1939- author.

Series:

Biomedical and health research ; Volume 78.

Biomedical and health research ; Volume 78

Language:

English

Subjects (All):

Nervous system--Diagnosis--Handbooks, manuals, etc.

Nervous system.

Physical Description:

1 online resource (1,424 pages).

Edition:

1st ed.

Place of Publication:

Amsterdam, Netherlands ; Berlin ; Washington, District of Colombia : IOS Press, [2019]

Summary:

The purpose of an exercise in differential diagnosis is to establish crosslinks between medical facts stored in different sections of our memory.This book, Differential Diagnosis in Neurology, is the unified perspective of an eminent physician with decades of clinical experience and teaching; one of the most skilled clinical neurologists of modern.

Contents:

Intro

Title Page

Foreword

Preface

Contents

CHAPTER 1. VASCULAR DISEASE

Ischemic Stroke

The Neurovascular Unit: Outline of Some Mechanisms Common to Stroke

Risk Factors for Ischemic Stroke

Risk Factors That Predict Stroke

Atherosclerosis

The Arterial Wall and Aneurysms

Collateral Circulation

Evolving Evaluation of Biomarkers in Acute Cerebrovascular Disease

The Natural History of Extracranial and Intracranial Atherosclerosis

Localization of Ischemic Lesions

Transient Ischemic Attacks (TIA)

Stroke Mimics

Differential Diagnosis of Stroke Mimics

Arterial Localization - (Arterial Topology/Stroke Localization)

Posterior Circulation Major Artery Strokes (Long Circumferential Arteries)

Border Zone Infarction

Multiple Infarctions

Lacunar Stroke

Small Vessel Disease

Retinal, Vestibular Small Vessel Diseases of the Brain

Venous Stroke

Medical Causes of Stroke

Autoimmune Disease and Stroke

Infectious Disease and Stroke

Stroke in Association with Named Vascular Syndromes

Vasculopathy

Vasoconstriction Syndromes and Stroke

Vascular Wall and Vasculopathy

Emboli and Valvular Disease

Ischemic Encephalopathy

Dilatative Arteriopathy

Stroke and Substance Abuse

Hemorrhagic Vascular Disease

Further Reading

CHAPTER 2. EPILEPSY

Overview of Epilepsy

Voltage-Gated Channel Integration

SCN1A Mutations

Potassium Channel Mutations

Calcium Channel Mutations

Epilepsy Mechanisms

Electrophysiology

Immune Seizures

Secondarily Generalized Tonic-Clonic Seizures (SPECT Imaging) Mechanisms

Cortical and Subcortical Network Analysis

Malformations of Cortical Development

Introduction to Epileptic Seizures

Differential Diagnosis of Causes of GTCS

Tonic Seizures

Localization Related Epilepsy.

Temporal Lobe Epilepsy

Differential Diagnosis in Epilepsy

CHAPTER 3. ANTERIOR HORN CELL DISEASE

Introduction

Adult Spinal Muscular Atrophies Linked to Chromosome 5q11.12-13.3

The Spinal Muscular Atrophies

Outline of dSMA (Hereditary Distal Motor Neuropathies)

Summary of Manifestations of Distal SMA

Differential Diagnosis of the Spinal Muscular Atrophies

Differential Diagnosis of Proximal Symmetric Weakness of Childhood to Early Adulthood Versus SMA (II, III, IV)

Diagnostic Features for SMA

Diagnostic Features of Kennedy's Disease

ALS

Differential Diagnosis of the Spinal Muscular Atrophy

Differential Diagnosis of Kennedy's Disease

Differential Diagnosis of Hirayama Disease

Differential Diagnosis of Scapuloperoneal Syndrome

Differential Diagnosis of Distal SMAs

Differential Diagnosis of Fazio-Londe and Brown-Vialetto-Van Laere Syndrome

Amyotrophic Lateral Sclerosis

CHAPTER 4. SPINAL CORD

Overview of Spinal Cord Anatomy

Spinal Cord Disease

Congenital Spinal Defects

Hereditary Spastic Paraplegias

Congenital Bony Defects That Compromise the Spinal Cord or Root Exit Foramina

Trauma to the Vertebral Column with Spinal Cord Injury

Arterial Spinal Cord Infarction Syndromes

Hemorrhagic Disease of the Spinal Cord

Rare Vascular Spinal Cord Malformations

Epidural Cavernous Hemangioma

Spinal Cord Veno-Occlusion

Hereditary Spastic Paraplegia

Differential Diagnosis of Hereditary Forms of Spastic Paraplegia

Metabolic Disorders Affecting the Spinal Cord

Selected Toxins That Affect the Spinal Cord

Autoimmune Causes of Spinal Cord Dysfunction

Infections of the Spinal Cord

Myelitis from Bacteria, Fungal and Parasitic Diseases

Differential Diagnosis of Granulomatous Spinal Cord Disease.

Meningomyelitis Caused by Fungi, Rare Organisms, and Major Parasites

Syphilis

Autoimmune Spinal Cord In ammation

Vitamin De ciencies with Spinal Cord Involvement

Spinal Cord Tumors

Primary Tumors of the Vertebral Column with Secondary Epidural Compression

Intradural Extramedullary Tumors

Metastatic Spinal Cord Tumors

Differential Diagnosis of Intrinsic Disc Disease with Spinal Cord Involvement

CHAPTER 5. RADICULOPATHY

Overview of Pain

General Features of Radicular Pain

Differential Diagnosis of Lumbar Radicular Pain

Differential Diagnosis of Pathologic Fractures

Disc Disease (Lumbar)

Cervical Disc Disease

Thoracic Root Disease

Lumbosacral Root Disease L1-L5

S1-S5

Epidural and Vertebral Metastasis

Differential Diagnosis of Radiculopathy

CHAPTER 6. PLEXUS

Cervical Plexus

The Brachial Plexus

Lumbosacral Plexus Lesions

CHAPTER 7. PERIPHERAL NEUROPATHY

Overview

Hereditary Peripheral Neuropathies Charcot-Marie-Tooth Disease (CMT)

Clinical Variants of CMT

Hereditary Neuropathy with Liability to Pressure Palsies (HNPP)

CMT2 Autosomal Dominant Axonal Neuropathies

Seminal Manifestations of the Clinical Variants of CMT2

Dominant Intermediate CMT

X-Linked CMT Disease

Impaired Mitochondrial Physiology

Other Hereditary Motor and Sensory Neuropathies

Hereditary Sensory and Autonomic Neuropathies

Rare Hereditary Neuropathies

Hereditary Ataxias with Neuropathy

Disorders of Defective DNA Repair

Other Hereditary Neuropathies

Guillain-Barré Syndrome and Its Variants

GBS Variants

The Differential Diagnosis of AIDP

Acute Peripheral Neuropathies

Chronic In ammatory Demyelinating Polyneuropathy and Related Autoimmune Neuropathies.

Systemic Vasculitis That Affect Large and Medium-Sized Vessels

Secondary Systemic Vasculitides

Differential Diagnosis of Vasculitic Neuropathy by Signs and Symptoms

Neuropathies of Systemic Disease

Neuropathies Associated with Infections

Toxic Neuropathies

Neuropathies Associated with Cancer

Tumor In ltration of Peripheral Nerve

In ltrating Tumors

Secondary Non-In ltrative Peripheral Neuropathies Associated with Lymphoproliferative Disorders and Plasmacytomas

Chemotherapy-Induced Peripheral Neuropathy (CIPN)

Endocrinopathies Associated with Neuropathy

Differential Diagnosis of DNC

Nutritional De ciencies and Neuropathy

Tumors of Peripheral Nerves

Malignant Peripheral Nerve Sheath Tumors (MPNST)

Traumatic and Compressive Neuropathies

Entrapment Neuropathies of the Lower Extremity

Unusual Entrapments Neuropathies

Non-Vasculitic Ischemic Nerve Injury

Differential Diagnosis of Neuropathy

CHAPTER 8. THE NEUROMUSCULAR JUNCTION

Neuromuscular Junction Disorders

Myasthenia Gravis (MG)

Defects in Endplate Development and Maintenance

Drugs/Toxins That Alter Neuromuscular Transmission

Drugs That Affect Neuromuscular Transmission

Drugs That Interfere with Neuromuscular Transmission

CHAPTER 9. MUSCLE DISEASES

Overview of Muscular Dystrophies

Dystrophin-Glycoprotein Complex and Related Proteins

An Overview of Muscle Contraction

Dystrophinopathies

LGMD (Limb Girdle Muscular Dystrophies)

Autosomal Dominant LGMD

Autosomal Recessive LGMD

Sarcoglycan Mutations

Congenital Muscular Dystrophy

Dystroglycanopathies

Rare Congenital Muscular Dystrophies

Regional Muscular Dystrophies

Distal Myopathy (Muscular Dystrophies)

Congenital Myopathies

Metabolic Myopathies.

Disorders of Muscle Carbohydrate Metabolism

Lysosomal Glycogen Storage Myopathies

Disorders of Purine Nucleotide Metabolism

Lipid Metabolic Disorders

Mitochondrial Myopathies

Muscle Channelopathies, Non-Dystrophic Myotonias and Periodic Paralysis

Chloride Channelopathies

Sodium Channelopathies

Potassium Aggravated Myotonias

Additional Calcium Channelopathies

In ammatory Myopathies

Rarer In ammatory Myopathies

Viral Infections

Bacterial Infection of Muscle

Parasitic Infections

Differential Diagnosis of Myositis Autoantibodies

Myopathies of Systemic Disease

Rare Myopathies Associated with Systemic Disease

Toxic Myopathies

Antimicrotubular Myopathies

Drug-Induced Mitochondrial Myopathy

Drug-Induced In ammatory Myopathies

Rare Drug-Induced In ammatory Myopathies

Myopathies Due to Impaired Protein Synthesis or Increased Catabolism

Multifactorial Toxic Myopathies

Myopathies of Drug Abuse

Differential Defects of Speci c Muscles

Congenital Facial Paresis

Congenital Diaphragmatic Hernia (CDH)

Congenital Hand Muscle Abnormalities

Axial Musculature

Abdominal Musculature

Rhabdomyolysis and Myoglobinuria

Differential Diagnosis of Genetic Causes of Rhabdomyolysis and Myglobinuria

Speci c Mitochondrial Depletion Syndromes of Adults

Thymidine Kinase De ciency (Myopathic Type)

Defects of Oxidative Phosphorylation Coupling

Defects of the Mitochondrial Respiratory Chain

Defects of Mitochondrial Substrate Utilization and Gluconeogenesis

Neural Disorders of Skeletal Muscle Overactivity

Metabolic Muscle Disease

Differential Diagnosis of Nondystrophic Myotonia and Periodic Paralysis

Further Reading on Muscle Diseases

CHAPTER 10. BRAINSTEM AND CRANIAL NERVES

The Regulation of Breathing.

The Medullary Respiratory Center.

Notes:

Description based on print version record.

Description based on publisher supplied metadata and other sources.

ISBN:

1-61499-966-X

OCLC:

1121133883