Problem solving through precision oncology / edited by Ellen R. Copson [and five others].

Format:

Book

Contributor:

Copson, Ellen R., editor.

Language:

English

Subjects (All):

Oncology.

Tumors.

Physical Description:

1 online resource (233 pages)

Edition:

1st ed.

Place of Publication:

Oxford, [England] : Clinical Publishing, 2017.

Summary:

A survey of best practice and collection of cases in precision oncology, and BMA Oncology Book of the Year.

Contents:

Intro

Contents

Contributors

Preface

Acknowledgements

Abbreviations

01 An Introduction to Precision Oncology

02 Testicular Cancer: a Successful Model for Biomarker-Guided Precision Cancer Care

03 Cancer Susceptibility Genes

04 Tumour Biology and Somatic Genetics as They Underpin Precision Oncology

05 Pharmacogenomics

06 Introducing Next Generation Sequencing into Routine Practice: the Benefits and Challenges

07 An Introduction to Proteomics and the Discovery of New Renal Cancer Biomarkers

08 Precision Medicine for Multiple Myeloma

09 Diffuse Large B Cell Lymphoma

10 Stratified Medicine in the UK

11 The Economic Challenge of Healthcare Provision in Precision Oncology

12 Clinical Trials in Precision Oncology

13 Developing Diagnostic Tests for Precision Oncology

14 Use of Circulating Tumour-Derived Nucleic Acids in Precision Oncology

15 Ethical Issues in Precision Oncology/Cancer Genetics

01 A Breast Cancer Patient with a BRCA1 Mutation

02 A Patient with DNA Mismatch Repair- Deficient Colorectal Cancer

03 A Patient with Advanced Melanoma for Systemic Therapy with a BRAF Inhibitor

04 Metastatic Non-Small-Cell Lung Carcinoma with Activating EGFR Mutation

05 A Patient with an Advanced Gastrointestinal Stromal Tumour Tested for a KIT Mutation, with Important Drug-Drug Interactions

06 A Man with a Mediastinal Sarcoma Receiving Neoadjuvant Therapy

07 A Patient with Relapsed Myeloma and High-Risk Cytogenetics

08 A Young Man with High-Grade Orbital Lymphoma

09 Li-Fraumeni Syndrome

10 Von Hippel-Lindau Disease and Renal Cancer

11 A Breast Cancer Patient Tested with Oncotype DX

12 A Patient with Ovarian Cancer for Whom Treatment Is Guided by Multiplatform Tumour Molecular Profiling.

13 A Teenager with a Small-Round-Blue- Cell Tumour and a Diagnostic Translocation

14 Treatment Based on Clinical Prognostic Factors and Molecular Profiling in Medulloblastoma

15 A Patient with Locally Advanced Human Papillomavirus-Positive Oropharyngeal Squamous Cell Carcinoma

16 A Colorectal Cancer Patient

17 A Patient with Advanced Upper Gastrointestinal Cancer and Poor Physical Fitness

18 A Patient with Localized Prostate Cancer

19 A Patient with BRCA-Mutated Ovarian Cancer

20 High-Count T Cell Acute Lymphoblastic Leukaemia with Treatment Stratification Based on Minimal Residual Disease Response

21 Application of Cancer Genomics to Routine Care.

Notes:

Description based on publisher supplied metadata and other sources.

Description based on online resource; title from PDF title page (EBook Central, viewed July 9, 2024).

ISBN:

9781846926532

184692653X