Neutropenia : Causes, Signs, Symptoms and Treatment / Mojtaba Akhtari, Ihab El-Hemaidi and Kam Newman, editors.

Format:

Book

Contributor:

Akhtari, Mojtaba, editor.

El-Hemaidi, Ihab, editor.

Newman, Kam, editor.

Series:

Recent advances in hematology research series.

Recent Advances in Hematology Research

Language:

English

Subjects (All):

Neutrophils.

Neutropenia.

Physical Description:

1 online resource (193 p.)

Place of Publication:

[Hauppauge], New York : Nova Science Publishers, 2015.

Language Note:

English

Summary:

This book discusses different aspects of neutropenia including drug-induced neutropenia, which is quite common, and neutropenia in chemotherapy-treated patients. The authors offer an all-encompassing approach to the pathobiology and treatment of neutropenic disorders. This book reviews current information concerning neutropenia. There have been significant advances in medicine; however, bacterial infections continue to contribute significantly to morbidity and mortality in patients with neutropenia particularly cancer patients who develop chemotherapy-induced neutropenia. In this setting, it i

Contents:

NEUTROPENIA: CAUSES, SIGNS, SYMPTOMS AND TREATMENT; NEUTROPENIACAUSES, SIGNS, SYMPTOMS AND TREATMENT; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Contributors List; Chapter 1: A Practical Approach to Neutropenia; Introduction; Epidemiology; Clinical Presentation; Workup; I. Congenial Neutropenic Syndromes; 1. Severe Congenital Neutropenia; 2. Hermansky Pudlak Syndrome Type 2; 3. Chediak-Highashi Syndrome; 4. Barth Syndrome; 5. Cohen Syndrome; 6. Cyclic Neutropenia; 7. Myelokathexis; 8. Glycogen Storage Disease Type 1b; II. Acquired Neutropenia; 1. Immune Neutropenia

Autoimmune Neutropenia in Felty's SyndromeAutoimmune Neutropenia in Systemic Lupus Erythematosus; Autoimmune Neutropenia due to Malignancy; Autoimmune Neutropenia due to Infections; 2. Drug-Induced Neutropenia; 3. Infection- Induced Neutropenia; 4. Hypersplenism; 5. Aplastic Anemia; 6. Bone Marrow Replacement; 7. Vitamin B12/Folate and Copper Deficiency; 8. Irradiation; 9. Acquired Disorders of Myeloid Stem Cells; 10. Granulomatous Diseases and Neutropenia; Management; Conclusion; References; Chapter 2: Drug-Induced Neutropenia; Introduction; Epidemiology and Risk Factors

Drugs Associated with Drug-Induced NeutropeniaPathophysiology; Clinical Presentation and Diagnosis; Prognosis; Management; Summary; References; Chapter 3: Neutropenia in Felty's Syndrome; Introduction; Background; Disease Characteristics; Clinical; Serum; Infections; Pathogenesis; Excessive Margination; Increased Sequestration and Peripheral Destruction; Impaired Granulopoiesis; Treatment; Corticosteroids; Methotrexate; Colony Stimulating Factors; Splenectomy; Hydroxychloroquine; Cyclosporine; Cyclophosphamide; Rituximab; D-penicillamine; Leflunomide; Etanercept; Historic Drugs

Large Granular LymphocytesCharacteristics; Pathogenesis; Treatment; Key Points; References; Chapter 4: Chemotherapy-Induced Neutropenia: Determinants, Consequences and Prevention; 1University of Nebraska Medical Center, Nebraska Medical Center, Omaha, NE, US; 2Memorial Hospital of Rhode Island, Department of Internal Medicine, Pawtucket, RI, US; 3Staten Island University Hospital, Department of Internal Medicine, Staten Island, NY, US

4Jane Anne Nohl Division of Hematology and Center for the Study of Blood Diseases, University of Southern California (USC)/ Norris Cancer Center, USC University Hospital, Keck Medical Center of USC, Los Angeles, CA, USIntroduction; Simplified Model of Myelosuppression; Determinants and Prediction Models; Consequences; Morbidity and Mortality; Impact on Subsequent Therapy; Economic Burden; Quality of Life; Prevention of CIN; Modifications in Chemotherapy; Prophylactic Antibiotic Therapy; Use of Granulocyte Colony-Stimulating Factor; Conclusion; References

Chapter 5: Mycobacterium tuberculosis and Non-tuberculous Mycobacterium Infections in Hematological Patients with Febrile Neutropenia

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on online resource; title from PDF title page (ebrary, viewed May 1, 2015).

ISBN:

1-63482-106-8