Bio-inspired nanomaterials and applications : nano detection, drug/gene delivery, medical diagnosis and therapy / edited by Donglu Shi.

Format:

Book

Contributor:

Shi, Donglu, editor.

Series:

Frontiers in nanobiomedical research ; Volume 4.

Frontiers in Nanobiomedical Research ; Volume 4

Language:

English

Subjects (All):

Nanostructures.

Physical Description:

1 online resource (257 p.)

Place of Publication:

Singapore ; Hackensack, New Jersey : World Scientific Publishing Company, 2015.

Language Note:

English

Summary:

This book intends to provide an up-to-date information in the field of nanobiomedicine. The focus of the book is on the basic concepts and recent developments in the field of nanotechnology. This book covers a broad spectrum of nanomaterials processing, structural characteristics, and related properties and will include bio-probes, medical imaging, drug delivery, and tumor diagnosis. Critical issues are addressed in a straightforward manner so those with no technical background and university students can benefit from the information. Furthermore, many novel concepts in nanomaterials are explained in light of current theories. An important aspect of the book lies on its wide coverage in practical biomedical applications. Not only are the cutting-edge technologies in modern medicine introduced, but also unique materials applications in many clinical areas.

Contents:

Contents; Preface; List of Contributors; Chapter 1 Up-Conversion Nanoparticles for Early Cancer Diagnosis; 1. Introduction of Up-Conversion Nanoparticles (UCNPs) in Nanomedicine; 2. Synthesis and Functionalization of UCNPs and Their Nanocomposites; 2.1. Synthetic approaches for UCNPs; 2.2. Surface modifications of UCNPs; 2.3. Fabrication of UCNP-based nanocomposites; 3. UCNPs and Their Nanocomposites for in vivo Biomedical Imaging; 3.1. Multicolor imaging; 3.2. Tumor-targeted molecular UCL imaging; 3.3. Multimodal imaging of UCNPs; 3.4. UCNPs for cell labeling and in vivo tracking

4. Summary and OutlookReferences; Chapter 2 Redox-Sensitive Polymeric Nanoparticles for Intracellular Drug Delivery; 1. Introduction; 2. Cellular Redox Environment; 3. Redox Trigger Employing Drug Delivery Systems; 3.1. Redox-sensitive micelles; 3.2. Redox-sensitive vesicles; 3.3. Redox-sensitive prodrugs; 3.4. Redox-sensitive dendrimers; 4. Dual Stimuli Engineered Redox Sensitivity; 4.1. pH/redox-sensitive polymeric NPs; 4.2. T/redox-sensitive polymeric NPs; 5. Multiple Stimuli Engineered Redox Sensitivity; 6. Conclusion and Perspectives; Acknowledgment; References

Chapter 3 Design of Biocompatible PEIs as Artificial Gene Delivery Vectors1. Introduction; 2. Biocompatible PEIs as Gene Delivery Vectors; 2.1. Pluronics-based PEIs; 2.2. Chitosan-based PEIs; 2.3. PEG-based PEIs; 2.4. Dextran-based PEIs; 3. Hydrolytically Degradable PEIs as Gene Delivery Vectors; 3.1. Ester-based PEIs; 3.2. Imine-based PEIs; 4. Conclusions; Acknowledgments; References; Chapter 4 Magnetic Fe3O4 Nanoparticles for Cancer Photothermal Therapy; 1. Photothermal Therapy; 2. NIR Light-Absorbing Nanomaterials for PTT; 3. Magnetic Iron Oxide Nanoparticles for Cancer PTT

3.1. Biomedical applications of the magnetic iron oxide nanoparticles and the advantages of PTT using magnetic iron oxide nanoparticles3.2. Photothermal conversion of the magnetic iron oxide nanoparticles; 3.3. PT T involving magnetic iron oxide nanoparticles in vitro; 3.4. PT T in vivo of the magnetic iron oxide nanoparticles; 4. Magnetic Iron Oxide Nanoparticles for MR Imaging Guided Cancer PTT; 5. Limitations of Cancer PTT and the Prospects for Fe3O4 Nanoparticle-Mediated Cancer PTT; References; Chapter 5 Nanomaterial-Based Sensors for Environmental Monitoring; 1. Introduction

2. Nanomaterial-Based Sensors in the Field of Environmental Monitoring2.1. Metal nanoparticle-based sensors; 2.2. Carbon-material-based sensors; 2.3. Semiconductor-material-based sensors; 3. Conclusions and Future Perspectives; References; Chapter 6 Janus Nanostructures and Their Bio-medical Applications; 1. Background; 1.1. Introduction to Janus particles; 1.2. Inorganic Janus particles; 1.3. Polymeric Janus particles; 1.4. Polymeric-inorganic Janus composites; 2. Preparation of Janus Composite Nanostructures via Miniemulsion

2.1. Janus polystyrene/silica composites via miniemulsion polymerization of monomer based on locally surface-modified inorganic particles

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

981-4616-92-3

OCLC:

922952146