Spear's surgery of the breast : principles and art / edited by Allen Gabriel [and three others].

Format:

Book

Contributor:

Gabriel, Allen, editor.

Standardized Title:

Surgery of the breast (Spear)

Language:

English

Subjects (All):

Breast--Cancer--Surgery.

Breast.

Physical Description:

1 online resource (xxv, 1310 pages)

Edition:

Fourth edition.

Place of Publication:

Philadelphia, Pennsylvania : Wolters Kluwer, 2021.

Summary:

Definitive, detailed, and multidisciplinary in scope, Surgery of the Breast: Principles and Art, Fourth Edition, remains the most comprehensive "how-to" reference on today's breast surgery. The text and its content have been thoroughly updated and carefully consolidated into one volume, to describe and demonstrates the most advanced and successful techniques for all types of oncological, reconstructive, and aesthetic breast surgeries--covering oncologic management of breast disease, breast reconstruction, reduction mammoplasty and mastopexy, augmentation mammoplasty, and more. Ideal for both plastic surgeons and general surgeons who perform a high volume of breast surgery, this classic text has been significantly revised to bring you fully up to date.

Contents:

Cover

Title Page

Copyright

Contributing Authors

Foreword

Preface

Contents

SECTION I: Breast Surgery and oncology

CHAPTER 1 Epidemiology of Breast Cancer: Incidence and Risk Factor

Incidence, Mortality, and Survival

Changing Trends and Migration

Risk Factors

Gender, Age, and Race

Early Life Events

Nutritional Factors

Alcohol

Smoking

Body Mass Index and Total Body Fat

Physical Activity

Benign Breast Disease

Breast Density

Growth Factors and Adult Height

Exogenous Hormones

Hormonal Contraceptives

Hormone Replacement Therapy

Family History And Genetics

Family History

Genetics

CHAPTER 2 Breast Cancer Screening and Diagnosis, Including the Surgically Altered Breast

History

Imaging in Women 40 to 70

The Argument Against Imaging

Policy Implications for Women 40 to 70

Breast Imaging After 70

High-Risk Screening

Imaging the Surgically Altered Breast

Conclusions and Current Imaging Guidelines Per Society (Tables 2-2 to 2-4)

CHAPTER 3 Molecular Pathology of the Breast

Molecular Diagnostics

Polymerase Chain Reaction

Gene Expression Profiling

Intrinsic Breast Cancer Subtypes

Clinical Applications

Oncotype Dx

Mammaprint

PAM50 (Prosigna)

Endopredict

Breast Cancer Index

Conclusions

CHAPTER 4 Defining and Managing the High-Risk Patient

Risk Stratification

Risk Assessment Models

Genetic Counseling And Testing

Approach to Managing the High-Risk Patient

Genetic Testing

Healthy Lifestyle

Risk-Reducing Agents

Risk-Reducing Surgery

Conclusion

CHAPTER 5 Heredity and Breast Cancer: Risk Assessment, Genetic Testing, and Management Options

Risk Factors for Breast Cancer

Breast Cancer Risk Assessment

Considerations When Conducting Genetic Testing.

Genes Associated With Breast Cancer Susceptibility

High-Penetrance Genes

Moderate-Penetrance Genes

Low-Penetrance Genes

Clinical Management of BRCA Pathogenic Variants

Screening and Prevention

Risk-Reducing Strategies: Surgeries and Chemoprevention

Screening of Male BRCA Carriers

Reproductive Considerations

Treatment Strategies in BRCA1/ 2-Related Cancers

Prognosis

Clinical Management of Other (Non-BRCA-Related) Hereditary Breast Syndromes

Psychosocial Issues in Inherited Breast and Ovarian Cancer Syndromes

CHAPTER 6 Patient Selection for Breast-Conservation Therapy

Patient Selection For Bct

History And Physical

Radiologic Evaluation

Patient Preferences Regarding Breast Conservation Versus Mastectomy

Contraindications For Bct

Pathologic Features of Breast Cancer

Post Bct Surveillance

CHAPTER 7 Axillary Nodal Recurrence

Rates of Axillary Nodal Recurrence

Risk Factors for Axillary Recurrence

Time to Axillary Nodal Recurrence

Diagnosis

Treatment And Prognosis

Summary

CHAPTER 8 Role of Nonsurgical Management of Breast Cancer: Endocrine Therapy and Tumor Ablation

Primary Endocrine Therapy

In Situ Ablation

Patient Selection

In Situ Ablation Techniques

Radiofrequency Ablation

LASER Thermotherapy

Microwave Ablation

Limitations

CHAPTER 9 Oncoplastic Approach to Maximizing the Lumpectomy-Level I

Goals and Benefits of Oncoplastic Breast Surgery

Level I Versus Level II Oncoplastic Techniques

Performing Level I Oncoplastic Surgery

Preoperative Evaluation

Operative Markings for Surgical Planning

Intraoperative Surgical Steps for Performing General Level I Procedures

Level I Oncoplastic Incisions/Techniques

Basic Incisions

Circumareolar Incision

Inframammary Incision.

Incisions That Include Resection of Skin

Incision With Skin Deepithelialization

Postoperative Complications of Level I Oncoplastic Surgery

CHAPTER 10 Oncoplastic Approach to Maximizing the Lumpectomy-Level II

Literature Review

Benefits of Oncoplastic Surgery

Safety

Patient Evaluation

Physical Examination

Imaging

Ideal Candidates for Level II Oncoplastic Surgery

Patients With Multifocal Tumors

Patients Who Desire Breast Reduction/Mastopexy

Patients With Large Tumors

Patients Who Desire Nipple-Sparing Mastectomy

Timing Of Operative Intervention

Technique

Volume Displacement Approaches

Volume Replacement Approaches

Management Of Central Tumors

CHAPTER 11 Breast Conservation Failure: When to Do a Completion Mastectomy

Declining Rate Of Events

Immediate Indications for Mastectomy

Diagnosis and Workup of IBTR

Treatment Of Ibtr

The Ipsilateral Breast: Mastectomy

The Ipsilateral Breast: Reconservation

The Axilla

The Contralateral Breast

Prognosis Following Ibtr

Follow Up Post Ibtr

CHAPTER 12 Radiation Therapy Following Breast-Conserving Surgery

Invasive Disease

Ductal Carcinoma In Situ

Omission of Radiation Therapy in Select Populations

Radiation Target Volume, Dose, and Fractionation

Regional Nodal Radiation Therapy

CHAPTER 13 The Surgical Management of Locally Advanced and Stage IV Breast Cancer

Locally Advanced Breast Cancer

Epidemiology

Systemic Treatment

Surgical Treatment

Stage Iv Breast Cancer

Inflammatory Breast Cancer

Neoadjuvant Systemic Treatment

Surgery

Adjuvant Treatment

Stage IV Inflammatory Breast Cancer

CHAPTER 14 Neoadjuvant and Adjuvant Systemic Therapy.

Prognostic Factors in Early Breast Cancer

Overview

Pathologic Factors

Genomic Profiles/Intrinsic Molecular Subtypes

Gene Expression Profiling for Early-Stage Breast Cancer

Circulating Tumor Cells

Neoadjuvant Therapy

Neoadjuvant Chemotherapy in TNBC

Neoadjuvant HER-2 Targeted Therapy

Neoadjuvant Endocrine Therapy

Treatment of Residual Disease Post Neoadjuvant Therapy

Treating Residual Disease in TNBC

Treating Residual Disease in HER-2-Positive Breast Cancer

Treating Residual Disease in HR-Positive Breast Cancer

Adjuvant Therapy

Adjuvant Chemotherapy

Chemotherapy-Related Side Effects

Adjuvant HER-2 Targeted Therapy

Principles of Adjuvant Endocrine Therapy

Bone-Modifying Therapy

CHAPTER 15 Breast Cancer Diagnosis, Prognosis, and Treatment in Augmented Women

Implants And Cancer Risk

Physical Examination of the Augmented Breast

Radiologic Imaging of the Augmented Breast

Mammography

Digital Mammography

Magnetic Resonance Imaging

Ultrasound

Effects of Implants on Disease Stage and Prognosis

Treatment of Breast Cancer in Augmented Patients

Acknowledgments

CHAPTER 16 Guidelines and Patient Selection Criteria for Nipple and Skin-Sparing Mastectomy

Indications

Contraindications

Preoperative Planning

OPERATIVE TECHNIQUE

Outcomes

CHAPTER 17 Invasive Carcinoma: Radiation Therapy After Mastectomy

Original Trials Supporting Use of Postmastectomy Radiation Therapy

Postmastectomy Radiation Therapy in Select Node-Negative Populations

Postmastectomy Radiation Therapy in Patients Receiving Neoadjuvant Chemotherapy

Side Effects of Postmastectomy Radiation Therapy

Conclusion.

CHAPTER 18 Optimizing Mastectomy Flaps Based on Breast Anatomy

Indications/Contraindications

Intraoperative Care

Postoperative Care

Generic Risks

CHAPTER 19 Male Breast Cancer: Surgery of the Breast

Clinical Presentation

Radiology

Pathology

Surgical Management

Medical Oncology Management

Radiation Oncology Management

CHAPTER 20 Breast Cancer Recurrence-Strategies for Risk Reduction

Mechanism of In-Breast Recurrence

Presentation of a Local/Regional Recurrence

Estimation of Risk of Recurrence

Invasive Breast Carcinoma

Multigene Assays

Recurrence Risk for DCIS

Extent of Surgery

Margins

Reconstruction

Role of Radiation Therapy

CHAPTER 21 Disease of the Breast, Benign to Premalignant

Hyperplasia to DCIS

Benign Disorders

Nonproliferative Lesions

Cystic Breast Mass

Proliferative Lesions Without Atypia

Atypical Hyperplasias

Radial Scars and Complex Sclerosing Lesions

Benign Neoplasms

Fibroadenoma

Phyllodes Tumor

Intraductal Papilloma

Nipple Adenoma

Miscellaneous Lesions

Inflammatory Conditions

Fat Necrosis

Mammary Duct Ectasia

Granulomatous Mastitis

Noninvasive Carcinoma

Lobular Carcinoma in Situ

Ductal Carcinoma in Situ

Workup

Biopsy

Pathologic Classification

Treatment

Breast-Conserving Therapy

Mastectomy

Radiation Therapy

Posttreatment Surveillance

CHAPTER 22 Breast Cancer Screening and Management in the Transgender Patient

Transmales

Transfemales

Transwomen.

Transmen.

Notes:

Includes bibliographical references and index.

Description based on print version record.

ISBN:

1-4963-9702-9

OCLC:

1273975096