Hepatotoxicity : symptoms, management and health implications / Senthilkumar Rajagopal and Sengottuvelan Murugan.

Format:

Book

Author/Creator:

Rajagopal, Senthilkumar, author.

Murugan, Sengottuvelan, author.

Series:

Hepatology research and clinical developments series.

Hepatology Research and Clinical Developments

Language:

English

Subjects (All):

Hepatotoxicology.

Liver--Diseases--Diagnosis.

Liver.

Physical Description:

1 online resource (382 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Biomedical, 2015.

Language Note:

English

Summary:

Over the past few years, epidemiological studies have revealed that there is an increase of life threatening liver diseases worldwide. It becomes increasingly clear that developments in this field are moving so rapidly toward the creation of new drugs against these maladies. Numerous research articles and books have been published on various aspects of toxicities, symptoms, managements and health implications of the liver. Consequently, a catalogue of collective information of toxicities, various features of natural products, and remedies for the prevention of toxicities is needed. This book deals with the toxicities in organs like the liver and the role natural products have in the preventing these ailments. It also analyzes trends in the processing of natural products by using nanotechnology and their health implications. The main purpose of this book is to exhibit relevant, modern information on hepatotoxicity, its symptoms, and treatments presented by internationally recognized experts in the field. Therefore, it is our belief that this book has covered some of the most interesting aspects of research in liver diseases and provides a trustworthy source of current information in this area of research which should prove useful to the scientists interested in this discipline throughout the world. This collection will interest a variety of other scientific disciplines including toxicology, genetics, medicine and pharmacology, as well as drug and food sciences. We hope that our readers will find this volume to be a delightful addition to their personal libraries, laboratories and offices. Additionally, it can be used as a required or recommended text for related courses taught at colleges and universities levels.

Contents:

HEPATOTOXICITY: SYMPTOMS,MANAGEMENT AND HEALTH IMPLICATIONS; HEPATOTOXICITY: SYMPTOMS,MANAGEMENT AND HEALTH IMPLICATIONS; Library of Congress Cataloging-in-Publication Data; Contents; Acknowledgments; Foreword A; Foreword B; Foreword C; About the Editors; Synopsis; Chapter 1: Alcoholic Hepatotoxicity: Symptoms and Managements; Abstract; 1. Introduction; 1.1. Liver; 1.1.1. Regulatory Functions of Liver; 1.2. Liver Toxicity; 1.2.1. Drug Induced Hepatotoxicity; 1.2.2. Marker Enzymes for Hepatotoxicity; 1.3. Alcohol; 1.3.1. Alcohol Metabolism in Liver; 1.3.2. Oxidative Metabolism of Ethanol

1.3.3. Non-Oxidative Metabolism of Ethanol1.4. Impact of Alcohol on Mitochondrial Functions; 1.5. Alcohol Effects on Erythrocyte; 1.6. Alcohol Effects on Stomach; 1.7. Alcohol Effects on Nervous System; 1.8. Alcohol Effects on the Liver; 2. Symptoms; 2.1. Signs and Symptoms of Alcohol Abuse; 2.2. Signs and Symptoms of Alcoholism; 3. Alcohol Management; 3.1. Initial Care Management; 3.2. Management for Alcohol Abuse; 3.3. Variable Treatments for Alcohol Abuse; 3.4. Herbal Treatments; Conclusion; References; Chapter 2: Potential Role of Polyphenols on Liver Health and Diseases; Abstract

ReferencesChapter 3: Pathology of Hepatotoxicity; Abstract; Introduction; Normal Liver; Laboratory Evaluation of Liver Disease; Blood Tests; Patterns of Hepatic injury; Complications; Symptoms of Liver Damage; Prevention of Drug Hepatotoxicity; Before Marketing; After Marketing; Conclusion; References; Chapter 4: Hepatoprotective Effect of Phloroglucinol from South Indian Marine Macroalgae against Liver Disorders; Abstract; 1. Introduction; 1.1. Risk Factors; 1.1.1. Virus Mediated Liver Injury; 1.1.2. Hepatitis B Viral Infection; 1.1.3. Hepatitis C Viral Infection

1.1.4. Drug Induced Liver Injury1.1.4.1. Rifampicin, Isoniazid (INH) Induced Hepatotoxicity; 1.1.4.2. Non Steroidal Anti-Inflammatory Drugs Induced Hepatotoxicity; 1.1.4.3. Anti HIV Drug Induced Hepatotoxicity; 1.1.4.4. Anti-Hyperlipidemic Drugs Induced Hepatotoxicity; 1.1.4.5. Alpha 1 - Antitrypsin Deficiency; 1.1.4.6. Aflatoxins; 1.3. Alcohol Induced Liver Injury; 1.4. Nonalcoholic Fatty Liver Damage (NAFLD); 1.4.1. Non-Alcoholic Steatohepatitis; 1.5. Schistosomal Infection Induced Liver Damage; 2. Hepatoprotective Agents; 2.1. Marine Environment; 2.1.1. Marine Algae

2.1.2. Marine Brown Algae

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on online resource; title from PDF title page (ebrary, viewed July 27, 2015).

Description based on publisher supplied metadata and other sources.

ISBN:

1-63482-695-7

OCLC:

918623976