Radiation biophysics / Edward L. Alpen.

Format:

Book

Author/Creator:

Alpen, Edward L.

Language:

English

Subjects (All):

Radiation--Physiological effect.

Radiation.

Biophysics.

Radiobiology.

Physical Description:

1 online resource (517 p.)

Edition:

2nd ed.

Place of Publication:

San Diego, Calif. : Academic Press, c1998.

Language Note:

English

Summary:

This newly revised and updated edition of Radiation Biophysics provides an in-depth description of the physics and chemistry of radiation and its effects on biological systems. Coverage begins with fundamental concepts of the physics of radiation and radioactivity, then progresses through the chemistry and biology of the interaction of radiation with living systems. The Second Edition of this highly praised text includes major revisions which reflect the rapid advances in the field. New material covers recent developments in the fields of carcinogenesis, DNA repair, molecular genetics,

Contents:

Front Cover; Radiation Biophysics; Copyright Page; Contents; Preface to the Second Edition; Preface to the First Edition; Introduction: An Historical Perspective; Chapter 1. Quantities, Units, and Definitions; Quantities and Units; Radiation Measurement; Radioactivity Measurements; References; Chapter 2. Electromagnetic Radiation: Its Nature and Properties; Introduction; Quantum Theory of Electromagnetic Radiation; Special Relativity; Relativistic Considerations of Mass and Velocity; Atomic Structure; De Broglie Wave Theory; References; Suggested Additional Reading; Problems

Chapter 3. RadioactivityIntroduction; Unit of Radioactivity; Law of Radioactive Decay; Radioactive Decay of Mixtures; Branching Decay Processes; Nomenclature of Radioactive Decay; Charting Decay Schemes; Nuclear Stability; Nuclear Mass and Binding Energy; Radioactive Decay by Alpha-Particle Emission; Negative Electron Emission Decay; Positive Electron Emission Decay; Decay by Electron Capture; Internal Conversion; References; Suggested Additional Reading; Problems; Chapter 4. Interaction of Radiation with Matter; Introduction; Linear Attenuation Coefficient

Energy Transfer and Energy AbsorptionMechanisms of Energy Transfer from Gamma Rays; Compton Scattering Process: Incoherent Scattering; Pair Production; Bremsstrahlung

Radiative Energy Loss; References; Suggested Additional Reading; Problems; Chapter 5. Energy Transfer Processes; Introduction; Importance of the Compton Process in Tissue Systems; Interaction of Charged Particles with Matter; Final Steps in Energy Absorption; Life History of a Fast Electron; Dose; Absorbed Dose and Kerma; Neutron Interactions in Tissue; Track Structure and Microdosimetry; References

Suggested Additional ReadingProblems; Chapter 6. Radiation Chemistry; Introduction; Stochastic Nature of Energy Transfer; Radiation Chemistry of Water; G Value: Expression of Yield in Radiation Chemistry; Reactions in the Track: The Role of Scavengers; Direct and Indirect Action; Recombination, Restitution, and Repair; Macromolecular Target in the Cell; Reactions of the Products of Water Radiolysis; Chain Scission in DNA; Role of DNA Configuration; Repair of DNA; Repair Fidelity; References; Suggested Additional Reading; Problems; Chapter 7. Theories and Models for Cell Survival; Introduction

Clonogenic SurvivalLea's Target Theory Model; Biological Survival Curves; Development of the Target Theory Model; Multitarget- Single-Hit Survival; Molecular Models for Cell Death; Molecular Theory of Radiation Action; Theory of Dual Radiation Action; Repair-Misrepair Model of Cell Survival; Lethal-Potentially Lethal Model; Summation; References; Suggested Additional Reading; Problems; Chapter 8. Survival Curve and Its Significance; Introduction; Technique of the Clonogenic Survival Curve; Characteristics of the Mammalian Cell Survival Curve; Significance of the Shoulder on the Survival Curve

Repair of Sublethal Damage

Notes:

Description based upon print version of record.

Includes bibliographical references and indexes.

ISBN:

1-281-07058-0

9786611070588

0-08-054020-1

OCLC:

476114602