Protein engineering : design, selection and applications / Mallorie N. Sheehan, editor.

Format:

Book

Contributor:

Sheehan, Mallorie N.

Series:

Protein biochemistry, synthesis, structure, and cellular functions series.

Protein Biochemistry, Synthesis, Structure and Cellular Functions

Language:

English

Subjects (All):

Protein engineering.

Physical Description:

1 online resource (237 p.)

Place of Publication:

New York : Nova Publishers, c2013.

Language Note:

English

Summary:

Protein engineering is the process of developing useful or valuable proteins. It is a young discipline, with much research currently taking place into the understanding of protein folding and protein recognition for protein design principles. There are two general strategies for protein engineering. The first is known as rational design, in which the scientist uses detailed knowledge of the structure and function of the protein to make desired changes. The second strategy is known as directed evolution and this is where random mutagenesis is applied to a protein, and a selection regime is used to pick out variants that have the desired qualities. This book presents and reviews important data on protein engineering, such as application of engineered proteins and cell adhesive surfaces as scaffolds or other biomedical devices which has the potential to promote tissue repair and regeneration for a wide variety of tissues including bone and skin.

Contents:

Synthesizing mammalian cell adhesive surfaces using self-assembling fibronectin domains / Patricia Pereira and Christopher F. van der Walle

Engineering thermobifida fusca cellulases : catalytic mechanisms and improved activity / Thu V. Vuong and David B. Wilson

An empirical study for finding a robust ensemble of classifiers for protein classification / Loris Nanni and Alessandra Lumini

Revolutionary protein engineering using molecular display / Mitsuyoshi Ueda

Chemoselective modification using aldehyde/ketone tags / Koichiro Kodama and Seketsu Fukuzawa

Computer modeling of the promising HIV-1 entry inhibitors for structure-based anti-AIDS drug design : cyclophilin B and GP120 V3 loop / Alexander M. Andrianov and Ivan V. Anishchenko

Molecular mechanisms of protein folding by mammalian ER chaperones and stress response / J. Geraldine Sandana Mala, Chellan Rose and Satoru Takeuchi

Protein engineering of calcium binding proteins / Eugene A. Permyakov and Vladimir N. Uversky.

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on online resource; title from title page (ebrary, viewed September 05, 2013).

ISBN:

1-61668-649-9