Flow cytometry for biotechnology / edited by Larry A. Sklar.

Format:

Book

Contributor:

Sklar, Larry A., editor.

Series:

Oxford scholarship online.

Oxford scholarship online

Language:

English

Subjects (All):

Flow cytometry.

Biotechnology.

Physical Description:

1 online resource (401 p.)

Place of Publication:

New York : Oxford University Press, 2020.

Language Note:

English

Summary:

Flow cytometry is uniquely capable of the precise and quantitative molecular analysis of genomic sequence information, interactions between purified biomolecules and cellular function. Combined with automated sample handling for increased sample throughput, these features make flow cytometry a versatile platform with applications at many stages of drug discovery. Traditionally, the particles studied are cells, especially blood cells; flow cytometry is used extensively in immunology. This volume shows how flow cytometry is integrated into modern biotechnology, dealing with issues of throughput, content, sensitivity and high throughput informatics with applications in various fields.

Contents:

Contents; Contributors; 1. The Future of Flow Cytometry in Biotechnology; 2. Fluorescent Probes; 3. Automation and High-Throughput Flow Cytometry; 4. Multispectral Imaging in Flow: A Technique for Advanced Cellular Studies; 5. Elastomeric Microfabricated Fluorescence-Activated Cell Sorters; 6. Flow Cytometry, Beads, and Microchannels; 7. DNA Fragment Sizing by High-Sensitivity Flow Cytometry: Applications in Bacterial Identification; 8. A Guide to Informatics and Flow Cytometry; 9. Molecular Assemblies, Probes, and Proteomics in Flow Cytometry

10. Multiparameter Analysis: Application to Vaccine Analysis11. FACS-Based High-Throughput Functional Screening of Genetic Libraries for Drug Target Discovery; 12. Applications of Flow Cytometry in Protein Engineering; 13. Applications of Flow Cytometry in Animal Reproduction; 14. Genetic Analysis Using Microsphere Arrays; 15. Uses of Flow Cytometry in Preclinical Safety Pharmacology and Toxicology; 16. Flow Cytometry and Cell Sorting in Plant Biotechnology; 17. Analysis of GTP-Binding Protein-Coupled Receptor Assemblies by Flow Cytometry

18. Applications of Flow Cytometry to Cell Adhesion Biology: From Aggregates to Drug DiscoveryIndex; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; X; Y; Z

Notes:

Previously issued in print: 2005.

Includes bibliographical references and index.

Description based on print version record and publisher information.

Description based on publisher supplied metadata and other sources.

ISBN:

0-19-756189-6

0-19-029303-9

1-280-42862-7

1-4237-3502-1

0-19-803478-4

1-60256-569-4

OCLC:

609202720