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Advances in Maternal-Fetal Biomedicine : Cellular and Molecular Mechanisms of Pregnancy Pathologies / edited by Marcelo Gonzalez-Ortiz.

Springer Nature - Springer Biomedical and Life Sciences eBooks 2023 English International Available online

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Format:
Book
Contributor:
González-Ortiz, Marcelo, editor.
Series:
Advances in Experimental Medicine and Biology, 2214-8019 ; 1428
Language:
English
Subjects (All):
Human physiology.
Reproductive health.
Reproduction.
Physiology.
Pharmacology.
Cytology.
Gynecology.
Human Physiology.
Reproductive Medicine.
Reproductive Physiology.
Cell Biology.
Local Subjects:
Human Physiology.
Reproductive Medicine.
Reproductive Physiology.
Pharmacology.
Cell Biology.
Gynecology.
Physical Description:
1 online resource (314 pages)
Edition:
1st ed. 2023.
Place of Publication:
Cham : Springer International Publishing : Imprint: Springer, 2023.
Summary:
This textbook aims to describe physiological and pathophysiological mechanisms that underlie human maternal-fetal interactions. The book emphasizes the structure and development of the fetoplacental unit, the endocrine and nutritional regulation of fetal development, nitric oxide signalling, solute carriers function and ion channels regulation in healthy pregnancies and diseases, like preeclampsia, gestational diabetes, and maternal obesity, among others. Also, we highlight novel mechanisms associated with language impairment in children, the use of serotonin inhibitors or cannabis during pregnancy, and maternal conditions' potential impact on cerebrovascular development in newborns and infants. The cellular and molecular understanding of maternal-fetal physiology and pathophysiology will allow the readers to understand the impact of diseases or conditions that are highly prevalent in pregnant women.
Contents:
Feto-Placental Unit: from development to function
Role of hormones during gestation and early development: pathways involved in developmental programming
Physiological and pathophysiological role of large-conductance calcium-activated potassium channels (BKCa) in HUVECs and placenta
Metabolic interaction between Folate, Vitamin B12 and Polyunsaturated Fatty Acids in pregnancy
Evidence of nitric oxide impairment during hypertensive pregnancies
Pathophysiology of preeclampsia and L-Arginine/L-citrulline supplementation as a potential strategy to improve birth outcomes
Maternal and fetal expression of ATP-binding cassette and Solute Carrier transporters involved in the brain disposition of drugs
Development of the placenta and brain are affected by selective serotonin reuptake inhibitors exposure during critical periods
The endocannabinoid system in placenta and respiratory central nervous system development: effects of prenatal exposure to cannabinoids
Impact of prenatal nicotine exposure on placental function and respiratory neural network development
Language impairment in children of mothers with gestational diabetes, preeclampsia, and preterm delivery: current hypothesis and potential underlying mechanisms
COVID-19 on pregnancy outcomes, mental health and placenta: focus in Latin America
The placental function beyond pregnancy: Insights from Latin America.
Notes:
Includes bibliographical references and index.
Other Format:
Print version: Gonzalez-Ortiz, Marcelo Advances in Maternal-Fetal Biomedicine
ISBN:
3-031-32554-0

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