Testosterone : From Basic to Clinical Aspects / edited by Alexandre Hohl.

Format:

Book

Author/Creator:

Hohl, Alexandre.

Series:

Medicine Series

Language:

English

Subjects (All):

Endocrinology.

Urology.

Sports medicine.

Reproductive health.

Sports Medicine.

Reproductive Medicine.

Local Subjects:

Endocrinology.

Urology.

Sports Medicine.

Reproductive Medicine.

Physical Description:

1 online resource (515 pages)

Edition:

2nd ed. 2023.

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2023.

Summary:

Even though research on testosterone is increasing, there is still much controversy regarding its physiology and clinical use. This book provides a broad overview on testosterone, from its basic features to the most recent evidence of clinical applicability. In addition, specific conditions in which testosterone play a pivotal role are discussed in detail, such as hypogonadism, misuse and abuse, puberty, cardiovascular effects and testosterone therapy. The testes are vital organs for reproduction of the human species, besides being the main source of testosterone production in men. Although not essential for survival, these singular structures represent the essence of male biological function. Testosterone is the most important testicular androgen in men. Low serum testosterone levels are associated with cardiovascular morbidity, metabolic syndrome, type 2 diabetes mellitus, atherosclerosis, osteoporosis, sarcopenia, and mortality. Also, there is increasing evidencethat serum testosterone is a major biomarker status of men's health in general. Hypogonadism in a male refers to a decrease in one or both of the two major functions of the testes: sperm production or testosterone production. These abnormalities can result from disease of the testes (primary hypogonadism) or disease of the pituitary or hypothalamus (secondary hypogonadism). Currently, the clinical features of male hypogonadism are sufficiently well-recognized, the causes are well-known, and the tests of the hypothalamic-pituitary-testicular axis are accurate enough for the diagnosis in most patients. Testosterone, the focus hormone of this book, is used in different forms and routes of administration. Several authors unravel its peculiarities and assist in choosing the most suitable form in each case, as well as the possible risks of its misuse or even abuse in men and women, seeking alternatives to help patients in this situation.

Contents:

The History of Testosterone: From Antiquity to Modern Times

Testosterone: Molecules and Receptors

Physiology of Male Gonadotropic Axis and Disorders of Sex Development

Utility and Limitations in Measuring Testosterone

Male Puberty: What Is Normal and Abnormal?

Gynecomastia

Hypogonadotropic and Hypergonadotropic Hypogonadism

Functional Hypogonadism

Male Hypogonadism and Aging

Male Hypogonadism and Traumatic Brain Injury

Male Hypogonadism and Fertility

Anabolic Steroid-Induced Hypogonadism

Testosterone Therapy: Oral, Buccal and Nasal Androgens

Testosterone Therapy: Transdermal Androgens

Testosterone Therapy: Injectable Androgens

Benefits and Adverse Events of Testosterone Therapy

Testosterone and Sexual Function

Testosterone Therapy and Prostate

Testosterone and Cardiovascular Effects

Testosterone and Women

Transgender Care and Testosterone Hormone Therapy

Testosterone and Endocrine Disruptors

Testosterone Misuse and Abuse.

Notes:

Description based on publisher supplied metadata and other sources.

Other Format:

Print version: Hohl, Alexandre Testosterone

ISBN:

3-031-31501-4

OCLC:

1392342564