Biomedical micro- and nanorobots in disease treatment : design, preparation, and applications / Chun Mao and Mimi Wan.

Format:

Book

Author/Creator:

Mao, Chun (Writer on microrobots), author.

Wan, Mimi, author.

Language:

English

Subjects (All):

Nanotechnology.

Nanomedicine.

Biomedical engineering.

Microrobots.

Robotics in medicine.

Diseases--Treatment--Technological innovations.

Diseases.

Physical Description:

1 online resource (253 pages)

Place of Publication:

Weinheim, Germany : WILEY-VCH GmbH, 2023.

Summary:

Biomedical Micro- and Nanorobots in Disease Treatment Comprehensive resource covering fundamentals at the micro and nano scales, technical advances in micro- and nanorobots, and their biomedical applications Biomedical Micro- and Nanorobots in Disease Treatment: Design, Preparation, and Applications provides foundational knowledge on the subject in the fields of biomaterials, nanotechnology, and biomedicine, discusses the applications of micro- and nanorobots in the cardiovascular, cancer, ophthalmic, orthopedic, gastrointestinal, and nervous system disease treatment, and addresses their biosafety, autonomous motion behavior, and future development trends. The two highly qualified authors comprehensively and systematically introduces the concept source, definition, classification, autonomous movement behavior, and functionality of the technology, providing readers with new ideas, technologies, and methods for modern biomedical research, while also expanding new disease diagnosis, treatment principles, and possible application modes to paint a complete picture of the potential of the technology. Sample topics covered in Biomedical Micro- and Nanorobots in Disease Treatment: Design, Preparation, and Applications include: Substrate selection between metal, inorganic, organic, natural, and hybrid materials, as well as driving systems based on biological components, external fields, and chemical reactions In vivo tracking technologies, including fluorescence imaging, magnetic resonance imaging (MRI), radionuclide and ultrasonic imaging, and other imaging methods Biosafety of micro- and nanorobot substrate through material composition, micro- and nanoscale influence, ultimate destiny, and genotoxicity Trending behavior mechanisms in magnetotactic, phototactic, and chemotaxis systems, and motion control through speed and direction control modes Study on therapeutic mechanism and application for various physiological diseases Summarizing research progress in the preparation, biosafety, functionality, and therapeutic effects of the technology, Biomedical Micro- and Nanorobots in Disease Treatment: Design, Preparation, and Applications is an important and timely resource for biochemists, materials scientists, medicinal chemists, pharmaceutical chemists, bioengineers, biotechnologists, and the greater biotechnological industry.

Contents:

Cover

Title Page

Copyright

Contents

Preface

Chapter 1 Introduction

1.1 Origin of Biomedical Micro‐ and Nanorobots

1.2 A Long Journey

1.3 Moment of Glory

1.4 Three Laws

1.5 Main Contents of this Book

References

Chapter 2 Definition and Classification

2.1 Definition

2.2 Classification

Chapter 3 Design and Preparation

3.1 Substrate Selection

3.1.1 Metal Materials

3.1.2 Inorganic Materials

3.1.3 Organic Materials

3.1.4 Natural Materials

3.1.5 Hybrid Materials

3.2 Driving System

3.2.1 Driving System Based on Biological Components

3.2.2 Driving System Based on External Fields

3.2.3 Driving System Based on Chemical Reactions

Chapter 4 Characterization

4.1 Characterization of Motion

4.1.1 In Aqueous Environment

4.1.2 In Complex Environments In Vitro

4.2 In Vivo Tracking Technologies

4.2.1 Fluorescence Imaging Technology

4.2.2 MRI Technology

4.2.3 Radionuclide Imaging Technology

4.2.4 Ultrasonic Imaging Technology

4.2.5 Other Imaging Methods

Chapter 5 Biosafety

5.1 Biosafety of Micro‐ and Nanorobot Substrate

5.1.1 Material Composition

5.1.2 Micro‐ and Nanoscale Influence

5.1.3 Interaction with Physiological Environment In Vivo

5.1.4 Ultimate Destiny

5.1.5 Genotoxicity

5.1.6 Research Method of Biosafety

5.2 Biosafety of Driving System of Micro‐ and Nanorobots

5.2.1 Biological Micro‐ and Nanorobots

5.2.2 Physical Field‐Driven Micro‐ and Nanorobots

5.2.3 Chemical Reaction‐Driven Micro‐ and Nanorobots

5.3 Biosafety of Autonomous Motion Behavior of Micro‐ and Nanorobots

5.4 Biosafety Evaluation Methods for Micro‐ and Nanorobots

Chapter 6 Autonomous Motion Behavior

6.1 Autonomous Motion Mechanism.

6.1.1 Motion Mechanism of Biological Micro‐ and Nanorobots

6.1.1.1 Bacteria

6.1.1.2 Sperm

6.1.1.3 Immune Cells

6.1.2 Motion Mechanism of Physical Field‐Driven Micro‐ and Nanorobots

6.1.2.1 Magnetic Field‐Driving Mode

6.1.2.2 Photic Driving Mode

6.1.2.3 Ultrasonic Field‐Driving Mode

6.1.3 Motion Mechanism of Chemical Reaction‐Driven Micro‐ and Nanorobots

6.1.3.1 Self‐Electrophoresis Mode

6.1.3.2 Self‐Diffusiophoresis Mode

6.1.3.3 Bubble Mode

6.2 Trend Behavior Mechanism

6.2.1 Magnetotactic System

6.2.2 Phototactic System

6.2.3 Chemotaxis System

6.3 Motion Control

6.3.1 Speed Control Mode

6.3.2 Direction Control Mode

6.3.3 Control of Start and Stop

Chapter 7 Functions

7.1 Moving in Complex Physiological Environment

7.2 Loading Power Source, Drug, or Imaging Agent

7.3 Targeting Specific Cells or Physiological Tissues

7.4 Promoting Cell Uptake and Improving Tissue Permeability

7.5 Imaging Capability

7.6 Information Interaction and Intelligent Decision

7.7 Diagnosis and Treatment of Disease

Chapter 8 For Cardiovascular Disease Treatment

8.1 Thrombus

8.2 Atherosclerosis

8.3 Cerebral Apoplexy

Chapter 9 For Cancer Treatment

9.1 Cancer Diagnosis

9.2 Targeting and Delivery

9.3 Treatment of Different Cancer Species

9.4 Treatment Mechanism

9.4.1 Chemotherapy

9.4.2 Metabolic Therapy

9.4.3 Gas Therapy

9.4.4 Optical Therapy

9.4.5 Biotherapy

9.4.6 Immunotherapy

9.4.7 Multimodal Combined Therapy

9.5 Theranostics

Chapter 10 For Other Diseases' Treatment

10.1 Ophthalmic Diseases

10.2 Orthopedic Diseases

10.3 Gastrointestinal Diseases

10.4 Neurological Diseases

10.5 Bacterial Infection

10.6 Blood Heavy Metal Poisoning

References.

Chapter 11 Future Development Trend

11.1 Biosafety of Micro‐ and Nanorobots

11.2 New Materials and Technologies of Micro‐ and Nanorobots

11.3 Intelligent Micro‐ and Nanorobots

11.4 New Treatment Mode

11.5 New Detection Technology for Micro‐ and Nanorobots

11.6 Outlook and Future Challenges

Postscript

Glossary

Index

EULA.

Notes:

Includes bibliographical references and index.

Description based on print version record.

ISBN:

9783527839773

3527839771

9783527839759

3527839755

OCLC:

1365769308