1 option
Advances in Pharmacokinetics and Pharmacodynamics / edited by Panos Macheras.
Springer Nature - Springer Biomedical and Life Sciences eBooks 2023 English International Available online
View online- Format:
- Book
- Author/Creator:
- Macheras, P. (Panos)
- Series:
- AAPS Introductions in the Pharmaceutical Sciences, 2522-8358 ; 9
- Language:
- English
- Subjects (All):
- Drug delivery systems.
- Drugs--Design.
- Drugs.
- Pharmaceutical chemistry.
- Metabolism.
- Pharmacology.
- Clinical biochemistry.
- Drug Delivery.
- Structure-Based Drug Design.
- Pharmaceutics.
- Medical Biochemistry.
- Local Subjects:
- Drug Delivery.
- Structure-Based Drug Design.
- Pharmaceutics.
- Metabolism.
- Pharmacology.
- Medical Biochemistry.
- Physical Description:
- 1 online resource (208 pages)
- Edition:
- 1st ed. 2023.
- Place of Publication:
- Cham : Springer International Publishing : Imprint: Springer, 2023.
- Summary:
- This book provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists.
- Contents:
- Pharmacokinetics
- Chapter 1: Current status in PBPK modeling
- Chapter 2: Physiologically based biopharmaceutics modeling (PBBM) Application on Food Effect Assessment
- Chapter 3: Physiologically based finite time pharmacokinetic (PBFTPK) models: Inception and development
- Chapter 4: Physiologically based finite time pharmacokinetic (PBFTPK) models: Applications
- Pharmacodynamics
- Chapter 5: Pharmacokinetic – Pharmacodynamic Modelling and Simulation in Clinical Practice and Studies
- Chapter 6: On the Verge of Impossibility: Accounting for Variability Arising from Permutations of Comorbidities that Affect the Fate of Drugs in the Human Body
- Chapter 7: Impact of Clinical Pharmacology on the Modernization of Drug Development and Regulation.
- Notes:
- Description based on publisher supplied metadata and other sources.
- Other Format:
- Print version: Macheras, Panos Advances in Pharmacokinetics and Pharmacodynamics
- ISBN:
- 9783031295416
- OCLC:
- 1380875404
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.