Nitric oxide in the kidney / Jennifer M. Sasser.

Format:

Book

Author/Creator:

Sasser, Jennifer M., author.

Series:

Colloquium digital library of life sciences.

Colloquium series on integrated systems physiology ; 2154-5626 # 56.

Colloquium Series on Integrated Systems Physiology: From Molecule to Function Disease, 2154-5626 ; Lecture Number 56

Language:

English

Subjects (All):

Kidneys--Pathophysiology.

Kidneys.

Nitric oxide--Pathophysiology.

Nitric oxide.

Nitric oxide--Physiological effect.

Physical Description:

1 online resource (58 p.)

Place of Publication:

[San Rafael, California] : Morgan & Claypool Life Sciences, 2015.

Language Note:

English

Summary:

Nitric oxide (NO) is a key regulator of various cellular signaling pathways throughout the body and plays an important role in renal function under normal physiological and pathophysiological conditions. NO plays a major role in the regulation of renal hemodynamics, tubuloglomerular feedback, sodium transport in the nephron, pressure natriuresis, and renal fibrosis and injury; moreover, a deficiency in NO is characteristic of chronic kidney disease in both human patients and in experimental animal models. The goal of this book is to highlight the actions of NO within the kidney and its effects on the regulation of renal blood flow and tubular transport.

Contents:

1. Introduction to nitric oxide

1.1 NO synthesis

1.2 Distribution of NOS isoforms within the kidney

1.3 Modulators of NO release

2. Regulation of renal hemodynamics by nitric oxide

2.1 Overview

2.2 Role of NO in renal autoregulation

2.3 Effects of NO on the release of renin

2.4 Effects of NO on renal medullary blood flow

3. Regulation of natriuresis by nitric oxide

3.1 Effects of NO on tubular function

3.2 Role of NO in pressure natriuresis

4. Role of nitric oxide in chronic kidney disease and hypertension

4.1 Nitric oxide deficiency in chronic kidney disease

4.2 Nitric oxide in diabetic nephropathy

4.3 The kidney in hypertension - role of nitric oxide

5. Summary

References

Author biography.

Notes:

Part of: Colloquium digital library of life sciences.

Includes bibliographical references.

Description based on online resource; title from PDF title page (ebrary, viewed June 13, 2015).

Cited in:

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ISBN:

1-61504-667-4

OCLC:

909811931