Management of Dysregulated Immune Response in the Critically Ill / edited by Zsolt Molnar, Marlies Ostermann, Manu Shankar-Hari.

Format:

Book

Contributor:

Molnár, Zsolt, editor.

Ostermann, Marlies, editor.

Shankar-Hari, Manu, editor.

Series:

Lessons from the ICU, Under the Auspices of the European Society of Intensive Care Medicine, 2522-5936

Language:

English

Subjects (All):

Critical care medicine.

Immunology.

Nephrology.

Cardiology.

Respiratory organs--Diseases.

Respiratory organs.

Intensive Care Medicine.

Pneumology.

Local Subjects:

Intensive Care Medicine.

Immunology.

Nephrology.

Cardiology.

Pneumology.

Physical Description:

1 online resource (325 pages)

Edition:

1st ed. 2023.

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2023.

System Details:

Mode of access: World Wide Web.

Summary:

This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new term introduced by the Sepsis-3 definitions in 2016. In contrast to systemic inflammatory response syndrome (SIRS) that has been used for nearly 30 years, this is a fundamentally new concept, which requires some sort of a paradigm shift in the way of thinking of critical care physicians. This change obviously requires time and after 5 years, time is ripe to summarize the knowledge in the form of a comprehensive book. The book is split in 4 sections. In the first one, the host immune response is explained in 11 chapters, followed by the next part, summarizing the possible tools for assessment at the bedside. The third and the fourth parts focus on the effects of dysregulated immune response on vital organ function and on the possible ways of immunomodulation. Written by internationally acclaimed experts of the field, the book is of value for all those intensivists and allied professionals working in ICUs.

Contents:

Foreword

Preface

Part I. The Host Immune Response

Phenotypes

The Dysregulated Host Response

What is Cytokine Storm?

Hemophagocytic Lymphohistiocytosis

Extracorporeal Circulation Related Immune response

Vasoplegic Shock

Part II. Assessing Dysregulated Immune Response at the Bedside

Pro- and anti-inflammatory biomarkers

How to interpret procalcitonin?

Assessment of the macro-, and microcirculation

Part III. Dysregulated Immune Response and organ dysfunction

Heart and circulation

Brain

Kidneys

Liver

Hemostasis

The muscles

Part IV. Modulating the immune response

The Role of Steroids

Why did Anti-Cytokine Therapies Fail in the Past?

Extracorporeal cytokine removal.

Notes:

Includes bibliographical references.

Description based on publisher supplied metadata and other sources.

Other Format:

Print version: Molnar, Zsolt Management of Dysregulated Immune Response in the Critically Ill

ISBN:

9783031175725

3031175727

OCLC:

1372557455