Epstein Barr virus volume 1 : one herpes virus: many diseases / edited by Christian Münz.

Format:

Book

Contributor:

Münz, Christian., Editor.

Series:

Current Topics in Microbiology and Immunology, 0070-217X ; 390

Language:

English

Subjects (All):

Virology.

Local Subjects:

Virology.

Physical Description:

1 online resource (387 p.)

Edition:

1st ed. 2015.

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2015.

Language Note:

English

Summary:

Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.

Contents:

Preface

History

Chap. 1 Why and How Epstein-Barr Virus was discovered 50 years ago - Anthony Epstein, University of Oxford, UK

Chap. 2. Tumor associations of EBV – historical perspectives - George Klein, Karolinska Institutet, Stockholm, Sweden

Chap. 3. EBV-specific immune response: early research and personal reminiscences – Denis J. Moss and Viviana P. Lutzky, Queensland Institute of Medical Research, Brisbane, Australia

Virus genetics and epigenetics

Chap. 4. Epstein Barr virus strain variation - Paul J. Farrell, Imperial College, London, UK

Chap. 5. Chromatin Structure of Epstein-Barr Virus Latent Episomes – Paul M. Lieberman, University of Pennsylvania, Philadelphia, USA

Chap. 6. The epigenetic life cycle of Epstein-Barr virus - Wolfgang Hammerschmidt, Helmholtz Center Munich, Germany. Chap. 7. Epstein-Barr virus: from the detection of sequence polymorphisms to the recognition of viral types - Regina Feederle, Olaf Klinke, Anton Kutikhin, Remy Poirey, Ming-Han Tsai and Henri-Jacques Delecluse, German Cancer Research Center, Heidelberg, Germany

Viral infection and associated diseases

Chap. 8. EBV persistence – introducing the virus – David A. Thorley-Lawson, Tufts University, Boston, USA

Chap. 9. Infectious mononucleosis – Samantha K. Dunmire, Kristin A. Hogquist and Henry H. Balfour, Jr., University of Minnesota, Minneapolis, USA

Chap. 10. Primary immunodeficiencies associated with EBV disease - Jeffrey I. Cohen, National Institutes of Health, Bethesda, USA

Chap. 11. Burkitt’s lymphoma – Rosemary Rochford and Ann M. Moormann, University of Massachusetts, Worcester, and Upstate University of New York, Syracuse, USA

Chap. 12. Contribution of the Epstein-Barr virus to the pathogenesis of Hodgkin lymphoma – Paul Murray and Andrew Bell, University of Birmingham, UK

Chap. 13. The role of EBV in the pathogenesis of diffuse large B cell lymphoma – Jane A. Healy and Sandeep S. Dave, Duke University, Raleigh, USA

Chap. 14. Nasopharyngeal carcinoma: an evolving role for the Epstein Barr virus – Nancy Raab-Traub, University of North Carolina, Chapel Hill, USA.-Chap. 15. EBV and autoimmunity – Alberto Ascherio and Kassandra Munger, Harvard University, Boston, USA

Index.

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

ISBN:

3-319-22822-6