The neurobiology of stress / edited by T. Steckler, N.H. Kalin, J.M.H.M. Reul.

Format:

Book

Contributor:

Steckler, T.

Kalin, N. H.

Reul, J. M. H. M.

Series:

Techniques in the behavioral and neural sciences ; v. 15.

Techniques in the behavioral and neural sciences, 0921-0709 ; v. 15

Handbook of stress and the brain ; pt. 1

Language:

English

Subjects (All):

Stress (Physiology)--Handbooks, manuals, etc.

Stress (Physiology).

Neuroendocrinology--Handbooks, manuals, etc.

Neuroendocrinology.

Physical Description:

1 online resource (857 p.)

Place of Publication:

Amsterdam ; London : Elsevier, 2005-

Language Note:

English

Summary:

The Handbook of Stress and the Brain focuses on the impact of stressful events on the functioning of the central nervous system; how stress affects molecular and cellular processes in the brain, and in turn, how these brain processes determine our perception of and reactivity to, stressful challenges - acutely and in the long-run. Written for a broad scientific audience, the Handbook comprehensively reviews key principles and facts to provide a clear overview of the interdisciplinary field of stress. The work aims to bring together the disciplines of neurobiology, physiology, immuno

Contents:

Front Cover; Handbook of Stress and the Brain: The Neurobiology of Stress; Copyright Page; Contents; List of Contributors; Preface; A Memorial for David de Wied (1925-2004); Section 1: Concepts of Stress; Chapter 1.1. Stress: an historical perspective; Chapter 1.2. The neuropsychology of stress; Chapter 1.3. An introduction to the HPA axis; Chapter 1.4. Hormones of the pituitary; Chapter 1.5. Molecular biology of the HPA axis; Chapter 1.6. The hypothalamic-pituitary-adrenal axis as a dynamically organized system: lessons from exercising mice

Section 2: Hypothalamic Hormones Involved in Stress ResponsivityChapter 2.1. Novel CRF family peptides and their receptors: an evolutionary analysis; Chapter 2.2. Molecular regulation of the CRF system; Chapter 2.3. Behavioral consequences of altered corticotropin-releasing factor activation in brain: a functionalist view of affective neuroscience; Chapter 2.4. The roles of urocortins 1, 2, and 3 in the brain; Chapter 2.5. Vasopressin and oxytocin; Chapter 2.6. The role of vasopressin in behaviors associated with aversive stimuli; Section 3: Stress and the HPA Axis

Chapter 3.1. Corticosteroid receptors and HPA-axis regulationChapter 3.2. Glucocorticoid effects on gene expression; Chapter 3.3. The role of 11ß-hydroxysteroid dehydrogenases in the regulation of corticosteroid activity in the brain; Chapter 3.4. Corticosteroids and the blood-brain barrier; Chapter 3.5. Glucocorticoids and motivated behaviour; Chapter 3.6. Effects of glucocorticoids on emotion and cognitive processes in animals; Chapter 3.7. Glucocorticoids: effects on human cognition; Section 4: Neurotransmitter Systems Involved in Stress Responsivity

Chapter 4.1. Neurocircuit regulation of the hypothalamo-pituitary-adrenocortical stress response - an overviewChapter 4.2. Sympatho-adrenal activity and hypothalamic-pituitary-adrenal axis regulation; Chapter 4.3. The locus coeruleus-noradrenergic system and stress: modulation of arousal state and state-dependent behavioral processes; Chapter 4.4. Functional interactions between stress neuromediators and the locus coeruleus-norepinephrine system; Chapter 4.5. Regional specialisation in the central noradrenergic response to unconditioned and conditioned environmental stimuli

Chapter 4.6. Stress, corticotropin-releasing factor and serotonergic neurotransmissionChapter 4.7. Modulation of glutamatergic and GABAergic neurotransmission by corticosteroid hormones and stress; Chapter 4.8. Neuroactive steroids; Chapter 4.9. Endogenous opioids, stress, and psychopathology; Chapter 4.10. Acetylcholinesterase as a window onto stress responses; Chapter 4.11. Pathways and transmitter interactions mediating an integrated stress response; Section 5: Neuroplasticity and Stress; Chapter 5.1. The intracellular signaling cascade and stress

Chapter 5.2. The role of neurotrophic factors in the stress response

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-281-05505-0

9786611055059

0-08-055324-9

OCLC:

476112321